(Q28564198)

English

Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain

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scholarly article

1 reference

31 January 2017

Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain (English)

1 reference

31 January 2017

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author name string

Sunil Kaul

1

1 reference

31 January 2017

Patrick J. M. Murphy

2

1 reference

31 January 2017

Jun Chen

3

1 reference

31 January 2017

Lloyd Brown

4

1 reference

31 January 2017

William B. Pratt

5

1 reference

31 January 2017

S. Stoney Simons

6

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31 January 2017

language of work or name

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publication date

27 September 2002

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31 January 2017

Journal of Biological Chemistry

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31 January 2017

277

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31 January 2017

36223–36232

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31 January 2017

39

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31 January 2017

Steroid receptor interactions with heat shock protein and immunophilin chaperones

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Reduced levels of hsp90 compromise steroid receptor action in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Stoichiometry, abundance, and functional significance of the hsp90/hsp70-based multiprotein chaperone machinery in reticulocyte lysate.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Probing conformational changes in the estrogen receptor: evidence for a partially unfolded intermediate facilitating ligand binding and release

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Steroid-induced conformational changes at ends of the hormone-binding domain in the rat glucocorticoid receptor are independent of agonist versus antagonist activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Molecular chaperones in cellular protein folding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Structural analysis of substrate binding by the molecular chaperone DnaK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Assisted protein folding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Modular structure of glucocorticoid receptor domains is not equivalent to functional independence. Stability and activity of the steroid binding domain are controlled by sequences in separate domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Binding of hsp90 to the glucocorticoid receptor requires a specific 7-amino acid sequence at the amino terminus of the hormone-binding domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

A glucocorticoid/retinoic acid receptor chimera that displays cytoplasmic/nuclear translocation in response to retinoic acid. A real time sensing assay for nuclear receptor ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Atomic structure of progesterone complexed with its receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Molecular basis of agonism and antagonism in the oestrogen receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

hsp90 is required for heme binding and activation of apo-neuronal nitric-oxide synthase: geldanamycin-mediated oxidant generation is unrelated to any action of hsp90.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): multiple motifs with different binding specificities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Ubc9 is a novel modulator of the induction properties of glucocorticoid receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Transactivation specificity of glucocorticoid versus progesterone receptors. Role of functionally different interactions of transcription factors with amino- and carboxyl-terminal receptor domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Comparison of DNA binding properties of activated, covalent and noncovalent glucocorticoid receptor-steroid complexes from HTC cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

The role of DnaJ-like proteins in glucocorticoid receptor.hsp90 heterocomplex assembly by the reconstituted hsp90.p60.hsp70 foldosome complex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Interaction between the amino- and carboxyl-terminal regions of the rat androgen receptor modulates transcriptional activity and is influenced by nuclear receptor coactivators.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Ligand-dependent, transcriptionally productive association of the amino- and carboxyl-terminal regions of a steroid hormone nuclear receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Interdomain communication regulating ligand binding by PPAR-gamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Opposing effects of corepressor and coactivators in determining the dose-response curve of agonists, and residual agonist activity of antagonists, for glucocorticoid receptor-regulated gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Progesterone receptor structure and function altered by geldanamycin, an hsp90-binding agent

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Geldanamycin, a heat shock protein 90-binding benzoquinone ansamycin, inhibits steroid-dependent translocation of the glucocorticoid receptor from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Interaction of the chicken progesterone receptor with heat shock protein (HSP) 90

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

A canonical structure for the ligand-binding domain of nuclear receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

The seven amino acids (547-553) of rat glucocorticoid receptor required for steroid and hsp90 binding contain a functionally independent LXXLL motif that is critical for steroid binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Interdomain signaling in a two-domain fragment of the human glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Activation Function 2 in the Human Androgen Receptor Ligand Binding Domain Mediates Interdomain Communication with the NH2-terminal Domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206748200

21 January 2018

Identifiers

10.1074/JBC.M206748200

1 reference

31 January 2017

1 reference

31 January 2017

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