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MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
title
MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress
(English)
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
main subject
protein ubiquitination
1 reference
based on heuristic
inferred from title
author name string
Yan Xia
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
Ji Wang
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
Shuichan Xu
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
Gary L. Johnson
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
Tony Hunter
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
Zhimin Lu
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
language of work or name
English
0 references
publication date
1 January 2007
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
published in
Molecular and Cellular Biology
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
volume
27
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
page(s)
510–517
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stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
issue
2
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
cites work
The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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19 March 2017
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
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PubMed Central
reference URL
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19 March 2017
JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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19 March 2017
Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase
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PubMed Central
reference URL
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19 March 2017
The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling
1 reference
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PubMed Central
reference URL
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19 March 2017
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
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PubMed Central
reference URL
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19 March 2017
Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
19 March 2017
The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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19 March 2017
Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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19 March 2017
Functions of c-Jun in liver and heart development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
19 March 2017
Control of cell cycle progression by c-Jun is p53 dependent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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19 March 2017
c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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19 March 2017
Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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19 March 2017
Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
19 March 2017
Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
19 March 2017
The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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19 March 2017
AP-1 as a regulator of cell life and death
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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7 April 2017
The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
2 references
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
7 April 2017
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17101801
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
AP-1: a double-edged sword in tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
9 May 2017
Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
E3 ubiquitin ligases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
MEKK1 regulates the AP-1 dimer repertoire via control of JunB transcription and Fra-2 protein stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
Physiological roles of SAPK/JNK signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
Role of JNK in tumor development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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29 September 2017
Scores of RINGS but No PHDs in Ubiquitin Signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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29 September 2017
Ubiquitylation of MEKK1 inhibits its phosphorylation of MKK1 and MKK4 and activation of the ERK1/2 and JNK pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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29 September 2017
AP-1 in mouse development and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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29 September 2017
Jun, the oncoprotein.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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29 September 2017
The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
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29 September 2017
Diverse functions of JNK signaling and c-Jun in stress response and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
Osmotic stress induces both secretion and apoptosis in rat alveolar type II cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
Activation of protein kinase C triggers its ubiquitination and degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
Insulin-like growth factor I rescues SH-SY5Y human neuroblastoma cells from hyperosmotic induced programmed cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
Structure-function analysis of the maf oncogene product, a member of the b-Zip protein family.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
The antimitogenic action of tumor necrosis factor is associated with increased AP-1/c-jun proto-oncogene transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
Transcriptional regulation of early growth response genes in FOS-expressing PC-12 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
29 September 2017
Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
3 June 2018
Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
3 June 2018
Oncogene jun encodes a sequence-specific trans-activator similar to AP-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
3 June 2018
v-jun encodes a nuclear protein with enhancer binding properties of AP-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
3 June 2018
c-fos mRNA, Fos, and Fos-related antigen induction by hypertonic saline and stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
3 June 2018
E3 ubiquitin ligases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
27 November 2018
The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
27 November 2018
Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
27 November 2018
Alterations of AP-1 and CREB protein DNA binding in rat supraoptic and paraventricular nuclei by acute and repeated hyperosmotic stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
27 November 2018
Induction of c-fos and c-jun mRNA expression by basic fibroblast growth factor in cultured rat Müller cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
27 November 2018
c-Jun is essential for normal mouse development and hepatogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1800814
retrieved
27 November 2018
A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17101801
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
c-Jun and p53 Activity Is Modulated by SUMO-1 Modification
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17101801
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.01355-06
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
PMCID
1800814
0 references
PubMed ID
17101801
1 reference
stated in
PubMed
PubMed ID
17101801
retrieved
31 January 2017
ResearchGate publication ID
6695427
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