(Q28567289)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17260022%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17260022%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

5

1 reference

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24 December 2019

author name string

Brun T

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17260022%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Duhamel DL

2

1 reference

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24 December 2019

Hu He KH

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17260022%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Wollheim CB

4

1 reference

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24 December 2019

language of work or name

English

0 references

publication date

29 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17260022%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17260022%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

26

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17260022%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

issue

29

2 references

31 January 2017

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24 December 2019

page(s)

4261-4271

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17260022%20AND%20SRC:MED&resulttype=core&format=json

The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets

24 December 2019

cites work

1 reference

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The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

21 April 2017

1 reference

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Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets

21 April 2017

1 reference

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21 April 2017

The Hallmarks of Cancer

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Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

21 April 2017

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Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families

21 April 2017

1 reference

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Beta-cell dysfunction in late-onset diabetic subjects carrying homozygous mutation in transcription factors NeuroD1 and Pax4

21 April 2017

1 reference

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Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR

21 April 2017

1 reference

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Expression of dominant negative form of PAX4 in human insulinoma

21 April 2017

1 reference

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A missense mutation of Pax4 gene (R121W) is associated with type 2 diabetes in Japanese

21 April 2017

1 reference

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PAX4 mutation (R121W) as a prodiabetic variant in Okinawans

21 April 2017

1 reference

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The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation

21 April 2017

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Telomeres and human disease: ageing, cancer and beyond

21 April 2017

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Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

21 April 2017

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Specificity and versatility in tgf-beta signaling through Smads

21 April 2017

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Activation of the interferon system by short-interfering RNAs

21 April 2017

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Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

21 April 2017

1 reference

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7 January 2021

Phosphorylated inositol compounds in beta -cell stimulus-response coupling

1 reference

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7 January 2021

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

1 reference

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7 January 2021

Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity

1 reference

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7 January 2021

Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor

1 reference

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7 January 2021

Opposing actions of Arx and Pax4 in endocrine pancreas development

1 reference

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7 January 2021

Cholesteryl ester transfer protein gene expression during differentiation of human preadipocytes to adipocytes in primary culture.

1 reference

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7 January 2021

Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes

1 reference

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7 January 2021

Transfection of melanoma cells with antisense PAX3 oligonucleotides additively complements cisplatin-induced cytotoxicity

1 reference

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7 January 2021

A moderate reduction of Bcl-x(L) expression protects against tumorigenesis; however, it also increases susceptibility to tissue injury

1 reference

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7 January 2021

Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells

1 reference

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7 January 2021

Growth factor-mediated proliferation and differentiation of insulin-producing INS-1 and RINm5F cells: identification of betacellulin as a novel beta-cell mitogen

1 reference

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7 January 2021

Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells.

1 reference

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7 January 2021

NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice

1 reference

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7 January 2021

Aberrant DNA demethylation in promoter region and aberrant expression of mRNA of PAX4 gene in hematologic malignancies

1 reference

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7 January 2021

PAX4 gene variations predispose to ketosis-prone diabetes

1 reference

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7 January 2021

Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

1 reference

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7 January 2021

Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival

1 reference

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7 January 2021

Reduced Pax2 gene dosage increases apoptosis and slows the progression of renal cystic disease

1 reference

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7 January 2021

A PANorama of PAX genes in cancer and development

1 reference

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7 January 2021

Betacellulin: a mitogen from pancreatic beta cell tumors

1 reference

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7 January 2021

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

1 reference

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7 January 2021

Ghrelin action in the brain controls adipocyte metabolism

1 reference

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7 January 2021

Replacement by a lacZ reporter gene assigns mouse connexin36, 45 and 43 to distinct cell types in pancreatic islets.

1 reference

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7 January 2021

The Arg121Trp variant in PAX4 gene is associated with beta-cell dysfunction in Japanese subjects with type 2 diabetes mellitus

1 reference

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7 January 2021

Activin A increases Pax4 gene expression in pancreatic beta cell lines

1 reference

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7 January 2021

Diabetes and pancreatic tumours in transgenic mice expressing Pa x 6.

1 reference

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7 January 2021

Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells

1 reference

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7 January 2021

Changes in the expression of transcription factors in pancreatic AR42J cells during differentiation into insulin-producing cells

1 reference

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7 January 2021

PAX6 suppresses growth of human glioblastoma cells.

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210205

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17260022%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 December 2019

0 references

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17260022%20AND%20SRC:MED&resulttype=core&format=json