(Q28567896)

31 January 2017

title

Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index (English)

1 reference

31 January 2017

1 reference

Mark D. Erion

1

1 reference

31 January 2017

Edward E. Cable

2

1 reference

31 January 2017

Bruce R. Ito

3

1 reference

31 January 2017

Hongjian Jiang

4

1 reference

31 January 2017

James M. Fujitaki

5

1 reference

31 January 2017

Patricia D. Finn

6

1 reference

31 January 2017

Bao-Hong Zhang

7

1 reference

31 January 2017

Jinzhao Hou

8

1 reference

31 January 2017

Serge H. Boyer

9

1 reference

31 January 2017

Paul D. van Poelje

10

1 reference

31 January 2017

David L. Linemeyer

11

1 reference

31 January 2017

language of work or name

English

0 references

publication date

25 September 2007

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 January 2017

published in

1 reference

31 January 2017

volume

104

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31 January 2017

issue

39

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31 January 2017

page(s)

15490–15495

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A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Tissue-specific actions of thyroid hormone: insights from animal models

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Physiological and molecular basis of thyroid hormone action

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

The c-erb-A gene encodes a thyroid hormone receptor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

The c-erb-A protein is a high-affinity receptor for thyroid hormone

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Mouse sterol response element binding protein-1c gene expression is negatively regulated by thyroid hormone

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

The thermogenic effect of thyroid hormone and its clinical implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Selective thyroid hormone receptor-beta activation: a strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Drug uptake systems in liver and kidney

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Thyroid hormone excess and glucose intolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Hormone selectivity in thyroid hormone receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Thyroid hormone receptors: multiple forms, multiple possibilities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

How the thyroid controls metabolism in the rat: different roles for triiodothyronine and diiodothyronines.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

The effect of altered thyroid function on the ultrastructure of the human liver

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

1-Aminocyclopropanephosphonate: time-dependent inactivation of 1-aminocyclopropanecarboxylate deaminase and Bacillus stearothermophilus alanine racemase by slow dissociation behavior.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: selective actions relative to 3,5,3'-triiodo-L-thyronine

3 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702759104

Design, synthesis, and characterization of a series of cytochrome P(450) 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702759104

Liver-targeted drug delivery using HepDirect prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702759104

Quantitation of rat liver messenger ribonucleic acid for malic enzyme during induction by thyroid hormone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702759104

Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702759104

Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702759104

Hepatic lipogenesis and cholesterol synthesis in hyperthyroid patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702759104

Metabolism of plasma triglycerides in hypothyroidism and hyperthyroidism in man

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978486

Transcriptional Regulation of Rat Hepatic Low-Density Lipoprotein Receptor and Cholesterol 7α Hydroxylase by Thyroid Hormone

27 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702759104

Cholesterol metabolism in hypothyroidism and hyperthyroidism in man

21 January 2018

1 reference

12 December 2020

Experimental hyperthyroidism in man: effects on plasma lipoproteins, lipoprotein lipase and hepatic lipase

1 reference

12 December 2020

A thyromimetic that decreases plasma cholesterol levels without increasing cardiac activity

1 reference

12 December 2020

Nuclear 3,5,3'-triiodothyronine receptor occupancy, phosphoenolpyruvate carboxykinase (PEPck) messenger ribonucleic acid levels and PEPck enzyme activity in rat liver

1 reference

12 December 2020

N-Phosphonomethyl dipeptides and their phosphonate prodrugs, a new generation of neutral endopeptidase (NEP, EC 3.4.24.11) inhibitors

1 reference

12 December 2020

Changes in carnitine palmitoyltransferase-I mRNA abundance produced by hyperthyroidism and hypothyroidism parallel changes in activity

1 reference

12 December 2020

Synthesis and structure-activity relationships of oxamic acid and acetic acid derivatives related to L-thyronine

1 reference

12 December 2020

Expression of uncoupling protein-3 and mitochondrial activity in the transition from hypothyroid to hyperthyroid state in rat skeletal muscle

1 reference

12 December 2020

Thyroid hormone transporters

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0702759104

1 reference

release_h4gqz7fglrcttnht35sr5q2bna

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/h4gqz7fglrcttnht35sr5q2bna

24 November 2022

mapped directly with Wikidata item

1683797

1 reference

1 reference

1683797

1 reference