(Q28569296)

22 June 2017

title

A CD28 superagonistic antibody elicits 2 functionally distinct waves of T cell activation in rats (English)

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22 June 2017

1 reference

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Nora Müller

1

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22 June 2017

Jens van den Brandt

2

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22 June 2017

Francesca Odoardi

3

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22 June 2017

Denise Tischner

4

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22 June 2017

Judith Herath

5

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22 June 2017

Alexander Flügel

6

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22 June 2017

Holger M Reichardt

7

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22 June 2017

language of work or name

English

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publication date

1 April 2008

1 reference

Journal of Clinical Investigation

22 June 2017

published in

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22 June 2017

volume

118

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22 June 2017

issue

4

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22 June 2017

page(s)

1405-1416

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describes a project that uses

22 June 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2269726/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Inhibition of Notch signaling biases rat thymocyte development towards the NK cell lineage

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2269726

Mitogenic signals through CD28 activate the protein kinase Ctheta-NF-kappaB pathway in primary peripheral T cells

19 March 2017

1 reference

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Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

19 March 2017

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Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

19 March 2017

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Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

7 April 2017

1 reference

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Enhanced glucocorticoid receptor signaling in T cells impacts thymocyte apoptosis and adaptive immune responses

7 April 2017

1 reference

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Regulation of T-cell activation by the cytoskeleton

29 September 2017

1 reference

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Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis

29 September 2017

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Lymphocyte numbers and subsets in the human blood. Do they mirror the situation in all organs?

29 September 2017

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Emerging therapeutic targets in multiple sclerosis

29 September 2017

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CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs

29 September 2017

1 reference

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Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis

29 September 2017

1 reference

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Mechanisms of suppression by suppressor T cells

29 September 2017

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Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs

29 September 2017

1 reference

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The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.

29 September 2017

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Integrins and T cell-mediated immunity

29 September 2017

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Actin cytoskeletal dynamics in T lymphocyte activation and migration

29 September 2017

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The immune modulator FTY720 targets sphingosine 1-phosphate receptors

29 September 2017

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L-selectin in health and disease

29 September 2017

1 reference

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Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor

29 September 2017

1 reference

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Polyclonal expansion of regulatory T cells interferes with effector cell migration in a model of multiple sclerosis.

29 September 2017

1 reference

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Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist

27 November 2018

1 reference

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Lymphocyte lineages at mucosal effector sites: rat salivary glands

27 November 2018

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Gene transfer into CD4+ T lymphocytes: green fluorescent protein-engineered, encephalitogenic T cells illuminate brain autoimmune responses

27 November 2018

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Down-regulation of homing receptors after T cell activation

27 November 2018

1 reference

12 December 2020

CD28-mediated induction of proliferation in resting T cells in vitro and in vivo without engagement of the T cell receptor: evidence for functionally distinct forms of CD28

1 reference

12 December 2020

Mitogenic CD28 signals require the exchange factor Vav1 to enhance TCR signaling at the SLP-76-Vav-Itk signalosome

1 reference

12 December 2020

"Cytokine storm" in the phase I trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics

1 reference

12 December 2020

Sustained pre-TCR expression in Notch1IC-transgenic rats impairs T cell maturation and selection

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI32698

1 reference

22 June 2017

0 references

1 reference