(Q28571127)

31 January 2017

title

Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion (English)

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31 January 2017

Amy L. Howes

1

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31 January 2017

Jane F. Arthur

2

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31 January 2017

Tong Zhang

3

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31 January 2017

Shigeki Miyamoto

4

1 reference

31 January 2017

John W. Adams

5

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31 January 2017

Gerald W. Dorn

6

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31 January 2017

Elizabeth A. Woodcock

7

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31 January 2017

Joan Heller Brown

8

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31 January 2017

language of work or name

English

0 references

publication date

10 October 2003

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

278

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31 January 2017

issue

41

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31 January 2017

page(s)

40343–40351

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Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy

31 January 2017

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Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.

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Overexpression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block

21 January 2018

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Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

21 January 2018

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Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways

21 January 2018

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Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy

21 January 2018

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Cardiomyocyte apoptosis induced by Galphaq signaling is mediated by permeability transition pore formation and activation of the mitochondrial death pathway.

21 January 2018

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Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.

21 January 2018

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The role of phosphoinositide 3-kinase lipid products in cell function

21 January 2018

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Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

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Regulation of protein kinase B and 4E-BP1 by oxidative stress in cardiac myocytes

21 January 2018

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Involvement of cardiotrophin-1 in cardiac myocyte-nonmyocyte interactions during hypertrophy of rat cardiac myocytes in vitro

21 January 2018

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Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

21 January 2018

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Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

21 January 2018

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Intracoronary, adenovirus-mediated Akt gene transfer in heart limits infarct size following ischemia-reperfusion injury in vivo

21 January 2018

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Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance

21 January 2018

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Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival

21 January 2018

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The phosphoinositide-dependent kinase, PDK-1, phosphorylates conventional protein kinase C isozymes by a mechanism that is independent of phosphoinositide 3-kinase

21 January 2018

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Cardiotrophin-1 phosphorylates akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes

21 January 2018

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Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy

21 January 2018

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A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase

21 January 2018

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21 January 2018

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Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

21 January 2018

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Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.

21 January 2018

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Identification of determinants in the alpha-subunit of Gq required for phospholipase C activation

21 January 2018

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Physical and functional interactions of Galphaq with Rho and its exchange factors

21 January 2018

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Transgenic Galphaq overexpression induces cardiac contractile failure in mice

21 January 2018

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Signaling pathways for cardiac hypertrophy and failure

21 January 2018

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Low level of sarcolemmal phosphatidylinositol 4,5-bisphosphate in cardiomyopathic hamster (UM-X7.1) heart

21 January 2018

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Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction

21 January 2018

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Activated Gαq Inhibits p110α Phosphatidylinositol 3-Kinase and Akt

21 January 2018

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Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains

21 January 2018

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Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover

21 January 2018

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Expression of G qα and PLC-β in Scar and Border Tissue in Heart Failure Due to Myocardial Infarction

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M305964200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017