(Q28571670)

English

Ectopic expression of eIF2Bepsilon in rat skeletal muscle rescues the sepsis-induced reduction in guanine nucleotide exchange activity and protein synthesis

scientific journal article

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scholarly article

1 reference

PubMed publication ID

31 January 2017

Ectopic expression of eIF2Bepsilon in rat skeletal muscle rescues the sepsis-induced reduction in guanine nucleotide exchange activity and protein synthesis (English)

1 reference

PubMed publication ID

31 January 2017

0 references

regulation of guanyl-nucleotide exchange factor activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

positive regulation of guanyl-nucleotide exchange factor activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

negative regulation of guanyl-nucleotide exchange factor activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

0 references

author name string

Alexander P. Tuckow

1

1 reference

PubMed publication ID

31 January 2017

Thomas C. Vary

2

1 reference

PubMed publication ID

31 January 2017

Scot R. Kimball

3

1 reference

PubMed publication ID

31 January 2017

Leonard S. Jefferson

4

1 reference

PubMed publication ID

31 January 2017

publication date

1 August 2010

1 reference

PubMed publication ID

31 January 2017

American Journal of Physiology - Endocrinology and Metabolism

1 reference

PubMed publication ID

31 January 2017

299

1 reference

PubMed publication ID

31 January 2017

2

1 reference

PubMed publication ID

31 January 2017

E241–248

1 reference

PubMed publication ID

31 January 2017

Skeletal muscle hypertrophy and atrophy signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

19 March 2017

Reduced amino acid availability inhibits muscle protein synthesis and decreases activity of initiation factor eIF2B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

19 March 2017

Identification of domains within the epsilon-subunit of the translation initiation factor eIF2B that are necessary for guanine nucleotide exchange activity and eIF2B holoprotein formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

19 March 2017

Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

19 March 2017

Reconstitution and purification of eukaryotic initiation factor 2B (eIF2B) expressed in Sf21 insect cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

19 March 2017

Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

19 March 2017

Identification of interprotein interactions between the subunits of eukaryotic initiation factors eIF2 and eIF2B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

19 March 2017

Subunit assembly and guanine nucleotide exchange activity of eukaryotic initiation factor-2B expressed in Sf9 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

19 March 2017

Regulation of eukaryotic initiation factor-2B activity in muscle of diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

19 March 2017

The mechanism of eukaryotic translation initiation and principles of its regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

7 April 2017

Translational control by RGS2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Physiologic and molecular bases of muscle hypertrophy and atrophy: impact of resistance exercise on human skeletal muscle (protein and exercise dose effects).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Regulation of muscle protein synthesis during sepsis and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Glucocorticoids and TNFalpha interact cooperatively to mediate sepsis-induced leucine resistance in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Sepsis-induced suppression of skeletal muscle translation initiation mediated by tumor necrosis factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Resistance exercise, muscle loading/unloading and the control of muscle mass.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Control of muscle size during disuse, disease, and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

eIF2B, a mediator of general and gene-specific translational control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Molecular mechanisms involved in muscle wasting in cancer and ageing: cachexia versus sarcopenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

The molecular basis of skeletal muscle atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Control of the size of the human muscle mass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Characterization of the initiation factor eIF2B and its regulation in Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Eukaryotic initiation factor eIF2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

High-efficiency gene transfer into skeletal muscle mediated by electric pulses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Expression of initiation factor genes in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Hepatic and systemic metabolic responses to aerobic and anaerobic intra-abdominal abscesses in a highly reproducible chronic rat model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Cytokines and glucocorticoids in the regulation of the "hepato-skeletal muscle axis" in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

29 September 2017

Defective translational control facilitates vesicular stomatitis virus oncolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

3 June 2018

Glycogen synthase kinase-3 is the predominant insulin-regulated eukaryotic initiation factor 2B kinase in skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

3 June 2018

Cloning and characterization of complementary and genomic DNAs encoding the epsilon-subunit of rat translation initiation factor-2B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

3 June 2018

A rapid and convenient technique for measuring the rate of protein synthesis in tissues by injection of [3H]phenylalanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

3 June 2018

Age-dependent decrease in the amount of eukaryotic initiation factor 2 in various rat tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

3 June 2018

Sepsis-induced changes in protein synthesis: differential effects on fast- and slow-twitch muscles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928514

3 June 2018

Eukaryotic initiation factors and protein synthesis after resistance exercise in rats.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00151.2010

21 January 2018

Insulin-facilitated increase of muscle protein synthesis after resistance exercise involves a MAP kinase pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00151.2010

21 January 2018

Lipopolysaccharide regulates proinflammatory cytokine expression in mouse myoblasts and skeletal muscle

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00151.2010

21 January 2018

Phosphorylation of eukaryotic translation initiation factor 2Bepsilon by glycogen synthase kinase-3beta regulates beta-adrenergic cardiac myocyte hypertrophy.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00151.2010

21 January 2018

Age-related deficit in load-induced skeletal muscle growth

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00151.2010

21 January 2018

Severe diabetes inhibits resistance exercise-induced increase in eukaryotic initiation factor 2B activity

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00151.2010

21 January 2018

Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00151.2010

21 January 2018

Alterations in the expression of mRNAs and proteins that code for species relevant to eIF2B activity after an acute bout of resistance exercise

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00151.2010

21 January 2018

Lipopolysaccharide and TNF-alpha produce very similar changes in gene expression in human endothelial cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00151.2010

21 January 2018

Altered expression of eukaryotic initiation factor 2B in skeletal muscle during sepsis.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00151.2010

21 January 2018

Phosphorylation of eukaryotic initiation factor eIF2Bepsilon in skeletal muscle during sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle fiber type composition of the rat hindlimb

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Skeletal Muscle Protein Synthesis in Septic Intra-abdominal Abscess

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of diabetes on guanine nucleotide exchange factor activity in skeletal muscle and heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of eukaryotic initiation factor-2 expression during sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of monoclonal antibodies to study the structure and function of eukaryotic protein synthesis initiation factor eIF-2B

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 receptor antagonist prevents sepsis-induced inhibition of protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of peptide-chain initiation in muscle during sepsis by interleukin-1 receptor antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implication of eIF2B rather than eIF4E in the regulation of global protein synthesis by amino acids in L6 myoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-binding protein ameliorates inhibition of skeletal muscle protein synthesis during sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of protein synthesis after acute resistance exercise in diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin-induced decrease in muscle protein synthesis is associated with changes in eIF2B, eIF4E, and IGF-I

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute oral leucine administration stimulates protein synthesis during chronic sepsis through enhanced association of eukaryotic initiation factor 4G with eukaryotic initiation factor 4E in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of skeletal muscle protein synthesis by amino acids and insulin during sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPENDO.00151.2010

1 reference

PubMed publication ID

31 January 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

PubMed publication ID

31 January 2017

ResearchGate publication ID

0 references

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