(Q28573899)

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A prohormone convertase cleavage site within a predicted alpha-helix mediates sorting of the neuronal and endocrine polypeptide VGF into the regulated secretory pathway

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scholarly article

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31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221685%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

A prohormone convertase cleavage site within a predicted alpha-helix mediates sorting of the neuronal and endocrine polypeptide VGF into the regulated secretory pathway (English)

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221685%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Deanna L. Benson

7

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8 January 2020

Stephen R Salton

8

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8 January 2020

author name string

Shan-Kuo Han

2

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31 January 2017

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8 January 2020

Timothy Ito

5

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31 January 2017

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8 January 2020

Angelo L Garcia

1

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8 January 2020

William G Janssen

3

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8 January 2020

Zin Z Khaing

4

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8 January 2020

Marc J Glucksman

6

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8 January 2020

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publication date

12 October 2005

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8 January 2020

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14

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Journal of Biological Chemistry

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31 January 2017

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8 January 2020

280

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31 January 2017

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8 January 2020

50

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31 January 2017

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8 January 2020

41595-41608

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8 January 2020

Sorting out genes that regulate epithelial and neuronal polarity.

1 reference

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21 January 2018

Sorting and storage during secretory granule biogenesis: looking backward and looking forward

1 reference

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21 January 2018

Protein hormone storage in secretory granules: mechanisms for concentration and sorting

1 reference

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21 January 2018

Comparative sorting of neuroendocrine secretory proteins: a search for common ground in a mosaic of sorting models and mechanisms

1 reference

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21 January 2018

Secretory granule biogenesis: rafting to the SNARE.

1 reference

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21 January 2018

Molecular cloning of a gene sequence regulated by nerve growth factor

1 reference

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21 January 2018

Nucleotide sequence and regulatory studies of VGF, a nervous system-specific mRNA that is rapidly and relatively selectively induced by nerve growth factor.

1 reference

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21 January 2018

Expression and polarization of VGF in developing hippocampal neurons.

1 reference

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21 January 2018

Expression, processing, and secretion of the neuroendocrine VGF peptides by INS-1 cells

1 reference

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21 January 2018

VGF: a novel role for this neuronal and neuroendocrine polypeptide in the regulation of energy balance

1 reference

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21 January 2018

Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance

1 reference

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21 January 2018

Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells

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21 January 2018

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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21 January 2018

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

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21 January 2018

A signal sequence is sufficient for green fluorescent protein to be routed to regulated secretory granules

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21 January 2018

Furin-independent pathway of membrane type 1-matrix metalloproteinase activation in rabbit dermal fibroblasts.

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21 January 2018

Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10.

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21 January 2018

A targeting signal in VAMP regulating transport to synaptic vesicles

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21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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21 January 2018

Sorting of carboxypeptidase E to the regulated secretory pathway requires interaction of its transmembrane domain with lipid rafts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

The disulfide-bonded loop of chromogranin B mediates membrane binding and directs sorting from the trans-Golgi network to secretory granules

1 reference

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21 January 2018

Characterization of GABAergic neurons in hippocampal cell cultures

1 reference

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21 January 2018

Functional binding interaction identified between the axonal CAM L1 and members of the ERM family

1 reference

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21 January 2018

N-terminal proteolytic processing of porcine chromogranin A in parathyroid tissue

1 reference

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21 January 2018

Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

Insulin targeting to the regulated secretory pathway after fusion with green fluorescent protein and firefly luciferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

Sorting of the vasopressin prohormone into the regulated secretory pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

Sorting of a constitutive secretory protein to the regulated secretory pathway of exocrine cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

Lipid raft association of carboxypeptidase E is necessary for its function as a regulated secretory pathway sorting receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

Involvement of the membrane lipid bilayer in sorting prohormone convertase 2 into the regulated secretory pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins

1 reference

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21 January 2018

Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation

1 reference

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21 January 2018

Isolation and characterization of VGF peptides in rat brain. Role of PC1/3 and PC2 in the maturation of VGF precursor.

1 reference

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21 January 2018

Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

The Arg617-Arg618 cleavage site in the C-terminal domain of PC1 plays a major role in the processing and targeting of the enzyme within the regulated secretory pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

Trafficking of non-regulated secretory proteins in insulin secreting (INS-1) cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

A conserved alpha-helix at the amino terminus of prosomatostatin serves as a sorting signal for the regulated secretory pathway

1 reference

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21 January 2018

Coupling of the IP3 receptor/Ca2+ channel with Ca2+ storage proteins chromogranins A and B in secretory granules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509122200

21 January 2018

Localization of three types of the inositol 1,4,5-trisphosphate receptor/Ca(2+) channel in the secretory granules and coupling with the Ca(2+) storage proteins chromogranins A and B.

1 reference

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21 January 2018

Localization of the secretory granule marker protein chromogranin B in the nucleus. Potential role in transcription control

1 reference

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21 January 2018

Dibasic cleavage site is required for sorting to the regulated secretory pathway for both pro- and neuropeptide Y.

1 reference

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21 January 2018

Progastrin is directed to the regulated secretory pathway by synergistically acting basic and acidic motifs

1 reference

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21 January 2018

Essential role of the disulfide-bonded loop of chromogranin B for sorting to secretory granules is revealed by expression of a deletion mutant in the absence of endogenous granin synthesis

1 reference

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21 January 2018

The neuroendocrine protein VGF is sorted into dense-core granules and is secreted apically by polarized rat thyroid epithelial cells

1 reference

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21 January 2018

A predicted alpha -helix mediates targeting of the proprotein convertase PC1 to the regulated secretory pathway

1 reference

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21 January 2018

A protease processing site is essential for prorenin sorting to the regulated secretory pathway.

1 reference

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21 January 2018

The role of dibasic residues in prohormone sorting to the regulated secretory pathway. A study with proneurotensin

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21 January 2018

Insertion of dibasic residues directs a constitutive protein to the regulated secretory pathway

1 reference

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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1 reference

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21 January 2018

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1 reference

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1 reference

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21 January 2018

PC5-A-mediated processing of pro-neurotensin in early compartments of the regulated secretory pathway of PC5-transfected PC12 cells

1 reference

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21 January 2018

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

1 reference

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21 January 2018

Furin at the cutting edge: from protein traffic to embryogenesis and disease

1 reference

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21 January 2018

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

1 reference

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21 January 2018

cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases

1 reference

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21 January 2018

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1 reference

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21 January 2018

Identifiers

10.1074/JBC.M509122200

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221685%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221685%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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