(Q28575459)

31 January 2017

title

Knocking down HMGB1 using dendrimer-delivered siRNA unveils its key role in NMDA-induced autophagy in rat cortical neurons (English)

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31 January 2017

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Valentín Ceña

2

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ORCID Public Data File 2021

author name string

María D. Pérez-Carrión

series ordinal

1

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31 January 2017

publication date

1 October 2013

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31 January 2017

published in

Pharmaceutical Research

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31 January 2017

volume

30

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31 January 2017

issue

10

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31 January 2017

page(s)

2584–2595

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Autophagy as a regulated pathway of cellular degradation

31 January 2017

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Dendrimer-mediated siRNA delivery knocks down Beclin 1 and potentiates NMDA-mediated toxicity in rat cortical neurons.

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Autophagy gone awry in neurodegenerative diseases

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

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The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia.

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An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid

21 January 2018

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Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation

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High-mobility group box 1 (HMGB1) protein: friend and foe.

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HMG chromosomal proteins in development and disease

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High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes

21 January 2018

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Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

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Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

21 January 2018

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Gene silencing through RNA interference (RNAi) in vivo: strategies based on the direct application of siRNAs

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Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death

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HIF-1α is neuroprotective during the early phases of mild hypoxia in rat cortical neurons.

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Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line.

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Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity

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Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorn delivered siRNA.

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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How to interpret LC3 immunoblotting

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Excitotoxicity and the NMDA receptor--still lethal after eight years

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The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway

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HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain.

21 January 2018

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21 January 2018

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21 January 2018

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

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Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

21 January 2018

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Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure

21 January 2018

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12 December 2020

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

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12 December 2020

A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation.

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12 December 2020

Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation

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12 December 2020

Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype

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12 December 2020

Lifeguard/neuronal membrane protein 35 regulates Fas ligand-mediated apoptosis in neurons via microdomain recruitment

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12 December 2020

Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.

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12 December 2020

Denaturation studies on bovine pancreatic ribonuclease. Effect of trichloroacetic acid

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12 December 2020

Efficient, non-toxic hybrid PPV-PAMAM dendrimer as a gene carrier for neuronal cells

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12 December 2020

10.1007/S11095-013-1049-9

Identifiers

DOI

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31 January 2017

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