(Q28576186)

English

Ectopic expression of MHC class II genes (RT1.B(I) beta/alpha) in rat hepatocytes in vivo and in culture can be elicited by treatment with the pregnane X receptor agonists pregnenolone 16 alpha-carbonitrile and dexamethasone

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PubMed publication ID

31 January 2017

Ectopic expression of MHC class II genes (RT1.B(I) beta/alpha) in rat hepatocytes in vivo and in culture can be elicited by treatment with the pregnane X receptor agonists pregnenolone 16 alpha-carbonitrile and dexamethasone (English)

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PubMed publication ID

31 January 2017

pregnane X receptor agonist

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author name string

Braulio D. Jiménez

1

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31 January 2017

Lymarie Maldonado

2

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31 January 2017

Rolf H. Dahl

3

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31 January 2017

Linda C. Quattrochi

4

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31 January 2017

Philip S. Guzelian

5

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31 January 2017

language of work or name

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publication date

7 June 2002

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31 January 2017

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PubMed publication ID

31 January 2017

71

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31 January 2017

3

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31 January 2017

311–323

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31 January 2017

Hormones and resistance

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Molecular genetics of the P-450 superfamily

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Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes

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A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus antiglucocorticoids

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An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

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Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif

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Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element

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Humanized xenobiotic response in mice expressing nuclear receptor SXR.

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The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

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SXR, a novel steroid and xenobiotic-sensing nuclear receptor

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Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

1 reference

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Regulation of rat hepatic hydroxysteroid sulfotransferase (SULT2-40/41) gene expression by glucocorticoids: evidence for a dual mechanism of transcriptional control

1 reference

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The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

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Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

1 reference

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Identification by differential display of the IF1 inhibitor peptide of ATP synthase/ATPase as a gene inducible in rat liver by pregnenolone 16alpha-carbonitrile

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DNA sequencing with chain-terminating inhibitors

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Complete coding nucleotide sequence of cDNA for the class II RT1.B beta I chain of the Lewis rat.

1 reference

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Complete cDNA sequence coding for the MHC class II RT1.B alpha chain of the Lewis rat.

1 reference

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Hepatocyte culture in study of P450 regulation

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Regulation of MHC class II genes: lessons from a disease

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Phenotypic stability of adult rat hepatocytes in primary monolayer culture

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Influence of adrenocorticotropic hormone, somatotrophic hormone and pregnenolone-16α-carbonitrile on drug response and metabolism

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Effect of Various Steroids on the Hepatic Glucuronidation and Biliary Excretion of Bilirubin

1 reference

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Effects of pregnenolone‐16α‐carbonitrile on the metabolism of cholesterol in rat liver microsomes

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How are class II MHC genes turned on and off?

1 reference

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Functional requirement for class I MHC in CNS development and plasticity

1 reference

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Differential regulation of expression of the MHC class II molecules RT1.B and RT1.D on rat B lymphocytes: effects of interleukin-4, interleukin-13 and interferon-gamma

1 reference

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Genes within and flanking the major histocompatibility region are risk factors for diabetes, insulin resistance, hypertension, and microalbuminuria in African-American women

1 reference

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Major histocompatibility complex in the rat and blood pressure regulation.

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The major histocompatibility complex influences the development of chronic liver disease in male children and young adults with cystic fibrosis

1 reference

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HLA expression in human hepatocellular carcinoma

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MHC class II regulation in vivo in the mouse kidney.

1 reference

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Identification of an inducible form of cytochrome P-450 in human liver

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Identifiers

10.1016/S0024-3205(02)01643-0

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PubMed publication ID

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PubMed publication ID

31 January 2017

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