(Q28576822)

English

Cdc42 and RhoA have opposing roles in regulating membrane type 1-matrix metalloproteinase localization and matrix metalloproteinase-2 activation

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scholarly article

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PubMed publication ID

31 January 2017

Cdc42 and RhoA have opposing roles in regulating membrane type 1-matrix metalloproteinase localization and matrix metalloproteinase-2 activation (English)

1 reference

PubMed publication ID

31 January 2017

author name string

Eric Ispanovic

1

1 reference

PubMed publication ID

31 January 2017

Damiano Serio

2

1 reference

PubMed publication ID

31 January 2017

Tara L. Haas

3

1 reference

PubMed publication ID

31 January 2017

publication date

1 September 2008

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PubMed publication ID

31 January 2017

American Journal of Physiology - Cell Physiology

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PubMed publication ID

31 January 2017

295

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PubMed publication ID

31 January 2017

3

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PubMed publication ID

31 January 2017

C600–610

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PubMed publication ID

31 January 2017

Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.

1 reference

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Nischarin inhibits Rac induced migration and invasion of epithelial cells by affecting signaling cascades involving PAK.

1 reference

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Angiogenic effects of extracellular human immunodeficiency virus type 1 Tat protein and its role in the pathogenesis of AIDS-associated Kaposi's sarcoma

1 reference

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Production of cell lines secreting TAT fusion proteins.

1 reference

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Proteolytic remodeling of extracellular matrix

1 reference

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Shear stress-mediated cytoskeletal remodeling and cortactin translocation in pulmonary endothelial cells

1 reference

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MAPK signaling regulates endothelial cell assembly into networks and expression of MT1-MMP and MMP-2.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

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What tangled webs they weave: Rho-GTPase control of angiogenesis.

1 reference

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21 January 2018

Integrin-mediated signals regulated by members of the rho family of GTPases

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Rac regulates endothelial morphogenesis and capillary assembly

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Molecular basis of endothelial cell morphogenesis in three-dimensional extracellular matrices

1 reference

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Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model

1 reference

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Caveolae are a novel pathway for membrane-type 1 matrix metalloproteinase traffic in human endothelial cells

1 reference

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21 January 2018

Actin microfilaments play a critical role in endocytosis at the apical but not the basolateral surface of polarized epithelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

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Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion

1 reference

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Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis

1 reference

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21 January 2018

Diminished corneal angiogenesis in gelatinase A-deficient mice

1 reference

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Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

1 reference

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21 January 2018

Differential actions of PAR2 and PAR1 in stimulating human endothelial cell exocytosis and permeability: the role of Rho-GTPases

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

A role for Rac in Tiam1-induced membrane ruffling and invasion

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Involvement of RhoA/Rho kinase signaling in VEGF-induced endothelial cell migration and angiogenesis in vitro

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Reduced retinal angiogenesis in MMP-2-deficient mice

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Membrane type I-matrix metalloproteinase (MT1-MMP) is internalised by two different pathways and is recycled to the cell surface

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

c-Jun kinase mediates expression of VEGF induced at transcriptional level by Rac1 and Cdc42Hs but not by RhoA.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Rho mediates the shear-enhancement of endothelial cell migration and traction force generation.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Rho family GTPases regulate VEGF-stimulated endothelial cell motility

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

1 reference

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A signalling cascade involving PKC, Src and Cdc42 regulates podosome assembly in cultured endothelial cells in response to phorbol ester

1 reference

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Regulated von Willebrand factor secretion is associated with agonist-specific patterns of cytoskeletal remodeling in cultured endothelial cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

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Reconstituted high-density lipoprotein inhibits thrombin-induced endothelial tissue factor expression through inhibition of RhoA and stimulation of phosphatidylinositol 3-kinase but not Akt/endothelial nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Glucose-stimulated Cdc42 signaling is essential for the second phase of insulin secretion

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

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Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

The family of matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

21 January 2018

Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

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Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production

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https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

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Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1.

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00460.2007

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Flt-1-mediated down-regulation of endothelial cell proliferation through pertussis toxin-sensitive G proteins, beta gamma subunits, small GTPase CDC42, and partly by Rac-1.

1 reference

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21 January 2018

Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

1 reference

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Identifiers

10.1152/AJPCELL.00460.2007

1 reference

PubMed publication ID

31 January 2017

PubMed publication ID

1 reference

PubMed publication ID

31 January 2017

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