(Q30480366)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Ruey-Hwa Chen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Jean-Cheng Kuo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Won-Jing Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Pei-Rung Wu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

1 February 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

number of pages

13

1 reference

based on heuristic

inferred from page(s)

published in

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

172

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

619-631

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells

16 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Cdc42--the centre of polarity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Cell migration: Rho GTPases lead the way

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Restoration of p53 tumor-suppressor activity in human tumor cells in vitro and in their xenografts in vivo by recombinant avian adenovirus CELO-p53.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Cell migration: integrating signals from front to back

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Ras GTPases: integrins' friends or foes?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Structural determinants of integrin recognition by talin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

The phosphotyrosine binding-like domain of talin activates integrins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

DAP kinase-a proapoptotic gene that functions as a tumor suppressor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Novel bile acid derivatives induce apoptosis via a p53-independent pathway in human breast carcinoma cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Rho GTPases control polarity, protrusion, and adhesion during cell movement

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

A role for Cdc42 in macrophage chemotaxis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Integrin activation by dithiothreitol or Mn2+ induces a ligand-occupied conformation and exposure of a novel NH2-terminal regulatory site on the beta1 integrin chain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Rapid Ca2+-mediated activation of Rap1 in human platelets

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Cell migration: a physically integrated molecular process

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways.

28 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

Integrins control motile strategy through a Rho-cofilin pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

A role for alphabeta1 integrins in focal adhesion function and polarized cytoskeletal dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

DAP kinase activity is critical for C(2)-ceramide-induced apoptosis in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

DAP-kinase-mediated morphological changes are localization dependent and involve myosin-II phosphorylation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063680

DAP kinase links the control of apoptosis to metastasis

26 November 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200505138

TGF-beta induces apoptosis through Smad-mediated expression of DAP-kinase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16476779

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200505138

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16476779%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

16476779

1 reference