(Q28577933)

31 January 2017

title

Aging-dependent changes in rat heart mitochondrial glutaredoxins--Implications for redox regulation (English)

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31 January 2017

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7

Edward J. Lesnefsky

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31 January 2017

Xing-Huang Gao

1

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31 January 2017

Suparna Qanungo

2

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31 January 2017

Harish V. Pai

3

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31 January 2017

David W. Starke

4

1 reference

31 January 2017

Kelly M. Steller

5

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31 January 2017

Hisashi Fujioka

6

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31 January 2017

Janos Kerner

8

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31 January 2017

Mariana G. Rosca

9

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31 January 2017

Charles L. Hoppel

10

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31 January 2017

John J. Mieyal

11

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31 January 2017

publication date

1 January 2013

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31 January 2017

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31 January 2017

volume

1

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31 January 2017

page(s)

586–598

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Protein-thiol oxidation and cell death: regulatory role of glutaredoxins

31 January 2017

cites work

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Mechanisms of altered redox regulation in neurodegenerative diseases--focus on S--glutathionylation

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Glutaredoxin regulates apoptosis in cardiomyocytes via NFkappaB targets Bcl-2 and Bcl-xL: implications for cardiac aging

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What is the functional significance of the unique location of glutaredoxin 1 (GRx1) in the intermembrane space of mitochondria?

17 March 2017

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Functional, structural, and spectroscopic characterization of a glutathione-ligated [2Fe-2S] cluster in poplar glutaredoxin C1

17 March 2017

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The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria

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Characterization of human glutaredoxin 2 as iron-sulfur protein: a possible role as redox sensor

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Age-associated increases in oxidative stress and antioxidant enzyme activities in cardiac interfibrillar mitochondria: implications for the mitochondrial theory of aging

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Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide

17 March 2017

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Complex III releases superoxide to both sides of the inner mitochondrial membrane

17 March 2017

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17 March 2017

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Mitochondria and apoptosis

17 March 2017

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Reconciling the chemistry and biology of reactive oxygen species

7 April 2017

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Oxidized redox state of glutathione in the endoplasmic reticulum

7 April 2017

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Role of reactive oxygen species-mediated signaling in aging.

7 April 2017

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Perinuclear mitochondrial clustering creates an oxidant-rich nuclear domain required for hypoxia-induced transcription

29 September 2017

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Blockade of electron transport before ischemia protects mitochondria and decreases myocardial injury during reperfusion in aged rat hearts

29 September 2017

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Impaired iron status in aging research

29 September 2017

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Ischemic preconditioning: the role of mitochondria and aging

29 September 2017

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Glutaredoxin 2 knockout increases sensitivity to oxidative stress in mouse lens epithelial cells

29 September 2017

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Oxidative stress inhibits vascular K(ATP) channels by S-glutathionylation

29 September 2017

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Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity.

29 September 2017

1 reference

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The intermembrane space of mitochondria

29 September 2017

1 reference

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In vivo fluorescent detection of Fe-S clusters coordinated by human GRX2.

29 September 2017

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Thioredoxins and glutaredoxins: unifying elements in redox biology

29 September 2017

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A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's d

29 September 2017

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Attenuation of doxorubicin-induced cardiac injury by mitochondrial glutaredoxin 2.

29 September 2017

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Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: potential role of CYS residues in decreasing oxidative damage

29 September 2017

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29 September 2017

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Targeted disruption of the glutaredoxin 1 gene does not sensitize adult mice to tissue injury induced by ischemia/reperfusion and hyperoxia

29 September 2017

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Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system

29 September 2017

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Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria

29 September 2017

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How does iron-sulfur cluster coordination regulate the activity of human glutaredoxin 2?

29 September 2017

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Cell signaling. H2O2, a necessary evil for cell signaling

29 September 2017

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Radical medicine: treating ageing to cure disease

29 September 2017

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Oxidative phosphorylation analysis: assessing the integrated functional activity of human skeletal muscle mitochondria--case studies

29 September 2017

1 reference

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Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release

29 September 2017

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Oxidative stress inhibits MEKK1 by site-specific glutathionylation in the ATP-binding domain

29 September 2017

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Ischemia-reperfusion injury in the aged heart: role of mitochondria

29 September 2017

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Two subpopulations of mitochondria in the aging rat heart display heterogenous levels of oxidative stress

29 September 2017

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Glutaredoxin Exerts an Antiapoptotic Effect by Regulating the Redox State of Akt

29 September 2017

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Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K(+) channel in cardiac function and cardioprotection.

29 September 2017

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Organelle-specific initiation of cell death pathways

29 September 2017

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Mitochondria, oxygen free radicals, and apoptosis

29 September 2017

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Aging selectively decreases oxidative capacity in rat heart interfibrillar mitochondria

29 September 2017

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29 September 2017

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Deficiency of the reduced nicotinamide adenine dinucleotide dehydrogenase component of complex I of mitochondrial electron transport. Fatal infantile lactic acidosis and hypermetabolism with skeletal-cardiac myopathy and encephalopathy

29 September 2017

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Kinetic and mechanistic characterization and versatile catalytic properties of mammalian glutaredoxin 2: implications for intracellular roles

29 September 2017

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Production of reactive oxygen species by mitochondria: central role of complex III.

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Ca(v)1.2 calcium channel is glutathionylated during oxidative stress in guinea pig and ischemic human heart

27 November 2018

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Deferasirox decreases age-associated iron accumulation in the aging F344XBN rat heart and liver

27 November 2018

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Enhanced modification of cardiolipin during ischemia in the aged heart

27 November 2018

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Oxidative disassembly of the [2Fe-2S] cluster of human Grx2 and redox regulation in the mitochondria

27 November 2018

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Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria

27 November 2018

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Blockade of electron transport during ischemia protects cardiac mitochondria

27 November 2018

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27 November 2018

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Aging defect at the QO site of complex III augments oxyradical production in rat heart interfibrillar mitochondria

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4127417

Acute cadmium exposure inactivates thioltransferase (Glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis.

27 November 2018

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Increased left ventricular dysfunction in elderly patients despite successful thrombolysis: the GUSTO-I angiographic experience

27 November 2018

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The inactivation of Fe-S cluster containing hydro-lyases by superoxide.

27 November 2018

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The mitochondrial Ca(2+)-activated K(+) channel contributes to cardioprotection by limb remote ischemic preconditioning in rat

27 November 2018

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12 December 2020

Sensitivity of protein sulfhydryl repair enzymes to oxidative stress

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12 December 2020

Computational and mutational analysis of human glutaredoxin (thioltransferase): probing the molecular basis of the low pKa of cysteine 22 and its role in catalysis

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12 December 2020

Dithionite increases radical formation and decreases vasoconstriction in the lung. Evidence that dithionite does not mimic alveolar hypoxia

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Aging decreases electron transport complex III activity in heart interfibrillar mitochondria by alteration of the cytochrome c binding site

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12 December 2020

Thioltransferase is a specific glutathionyl mixed disulfide oxidoreductase

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12 December 2020

Riboflavin and rat hepatic cell structure and function. Mitochondrial oxidative metabolism in deficiency states

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Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle

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12 December 2020

10.1016/J.REDOX.2013.10.010

Identifiers

DOI

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