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Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
title
Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling
(English)
1 reference
stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
main subject
phosphorylation
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author
Jerrold M. Olefsky
series ordinal
4
object named as
Jerrold M. Olefsky
1 reference
stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
author name string
Satoshi Ugi
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
Takeshi Imamura
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
William Ricketts
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
language of work or name
English
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publication date
1 April 2002
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stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
published in
Molecular and Cellular Biology
1 reference
stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
volume
22
1 reference
stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
page(s)
2375–2387
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stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
issue
7
1 reference
stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
cites work
Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein
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Identification of structural elements involved in the interaction of simian virus 40 small tumor antigen with protein phosphatase 2A
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The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm
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The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling
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Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins
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B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein
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Evidence for a functional role of Shc proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor
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Protein phosphatase 2A: the Trojan Horse of cellular signaling
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29 September 2017
Pertussis toxin-sensitive and -insensitive thrombin stimulation of Shc phosphorylation and mitogenesis are mediated through distinct pathways
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A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction
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29 September 2017
Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 small t to promote cell growth and NF-kappaB activation
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29 September 2017
Novel protein serine/threonine phosphatases: variety is the spice of life
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29 September 2017
Stimulation of interleukin-8 production by okadaic acid and vanadate in a human promyelocyte cell line, an HL-60 subline. Possible role of mitogen-activated protein kinase on the okadaic acid-induced NF-kappaB activation
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29 September 2017
Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF7 cells treated with calyculin-A, okadaic acid, and tautomycin
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Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A.
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29 September 2017
Effect of tumor necrosis factor-alpha on insulin-stimulated mitogen-activated protein kinase cascade in cultured rat skeletal muscle cells
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29 September 2017
Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors
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29 September 2017
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29 September 2017
The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.
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29 September 2017
Simian virus 40 small-t antigen stimulates viral DNA replication in permissive monkey cells
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PubMed Central
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29 September 2017
Comparison of heterotrimeric protein phosphatase 2A containing different B subunits.
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PubMed Central
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29 September 2017
Complete interaction of cellular 56,000- and 32,000-Mr proteins with simian virus 40 small-t antigen in productively infected cells
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29 September 2017
Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase
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PubMed Central
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29 September 2017
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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29 September 2017
Constant expression and activity of protein phosphatase 2A in synchronized cells
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PubMed Central
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29 September 2017
The roles of the simian virus 40 tumor antigens in transformation of chinese hamster lung cells
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PubMed Central
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29 September 2017
Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells
1 reference
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PubMed Central
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29 September 2017
Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A.
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3 June 2018
Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila.
1 reference
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3 June 2018
Phosphatase 2A associated with polyomavirus small-T or middle-T antigen is an okadaic acid-sensitive tyrosyl phosphatase
1 reference
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PubMed Central
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3 June 2018
Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.
1 reference
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PubMed Central
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3 June 2018
Regulation of protein phosphatase 1 and 2A activities by insulin during myogenesis in rat skeletal muscle cells in culture.
1 reference
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PubMed Central
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3 June 2018
Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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3 June 2018
Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines.
1 reference
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PubMed Central
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3 June 2018
Interleukin-2-induced tyrosine phosphorylation of p52shc in T lymphocytes.
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PubMed Central
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3 June 2018
Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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3 June 2018
SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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3 June 2018
Inhibitory effect of okadaic acid on the p-nitrophenyl phosphate phosphatase activity of protein phosphatases
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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3 June 2018
Control of protein phosphatase 2A by simian virus 40 small-t antigen
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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3 June 2018
Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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27 November 2018
A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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27 November 2018
Cell cycle-dependent activation of Ras.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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27 November 2018
Insulin-induced phosphorylation of the 46- and 52-kDa Shc proteins.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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27 November 2018
Effects of phorbol ester on mitogen-activated protein kinase kinase activity in wild-type and phorbol ester-resistant EL4 thymoma cells.
1 reference
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PubMed Central
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27 November 2018
Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133677
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27 November 2018
Neurofilament-associated protein phosphatase 2A: its possible role in preserving neurofilaments in filamentous states.
1 reference
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PubMed Central
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27 November 2018
cAMP counter-regulates insulin-mediated protein phosphatase-2A inactivation in rat skeletal muscle cells
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/11884620
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Insulin-induced desensitization of extracellular signal-regulated kinase activation results from an inhibition of Raf activity independent of Ras activation and dissociation of the Grb2-SOS complex
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11884620
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effects of regulatory subunits on the kinetics of protein phosphatase 2A
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11884620
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of a phosphotyrosyl protein phosphatase activity associated with a phosphoseryl protein phosphatase of Mr = 95,000 from bovine heart
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11884620
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.22.7.2375-2387.2002
0 references
PMCID
133677
0 references
PubMed ID
11884620
1 reference
stated in
PubMed
PubMed ID
11884620
retrieved
31 January 2017
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