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Spi-B can functionally replace PU.1 in myeloid but not lymphoid development
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
title
Spi-B can functionally replace PU.1 in myeloid but not lymphoid development
(English)
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
main subject
Spleen focus forming virus (SFFV) proviral integration oncogene
1 reference
stated in
GOA release 2020-03-11
Recombination activating gene 2
1 reference
stated in
GOA release 2020-03-11
Myeloperoxidase
1 reference
stated in
GOA release 2020-03-11
Spi-B transcription factor (Spi-1/PU.1 related)
1 reference
stated in
GOA release 2020-03-11
author name string
Richard Dahl
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
Diana L. Ramirez-Bergeron
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
Sridhar Rao
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
M. Celeste Simon
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
language of work or name
English
0 references
publication date
1 May 2002
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
published in
The EMBO Journal
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
volume
21
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
page(s)
2220–2230
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stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
issue
9
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
cites work
SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
17 March 2017
Knock-in mutation of transcription factor GATA-3 into the GATA-1 locus: partial rescue of GATA-1 loss of function in erythroid cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
17 March 2017
CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
17 March 2017
PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
17 March 2017
Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
17 March 2017
Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
17 March 2017
The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
17 March 2017
Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
17 March 2017
PU.1/Spi-B regulation of c-rel is essential for mature B cell survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Evolution of hematopoiesis: Three members of the PU.1 transcription factor family in a cartilaginous fish, Raja eglanteria.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Fra-1 replaces c-Fos-dependent functions in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Do lampreys have lymphocytes? The Spi evidence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Prf, a novel Ets family protein that binds to the PU.1 binding motif, is specifically expressed in restricted stages of B cell development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Spi-C, a novel Ets protein that is temporally regulated during B lymphocyte development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Normal myeloid development requires both the glutamine-rich transactivation domain and the PEST region of transcription factor PU.1 but not the potent acidic transactivation domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
PU.1 and hematopoiesis: lessons learned from gene targeting experiments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
A novel, myeloid transcription factor, C/EBP epsilon, is upregulated during granulocytic, but not monocytic, differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
PU.1 can participate in an active enhancer complex without its transcriptional activation domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
The Ets protein Spi-B is expressed exclusively in B cells and T cells during development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Neutrophils and monocytes express high levels of PU.1 (Spi-1) but not Spi-B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
The Ets1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
Production of homozygous mutant ES cells with a single targeting construct
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
29 September 2017
The Ets factors PU.1 and Spi-B regulate the transcription in vivo of P2Y10, a lymphoid restricted heptahelical receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
3 June 2018
A critical role for PU.1 in homing and long-term engraftment by hematopoietic stem cells in the bone marrow.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
3 June 2018
Role of PU.1 in hematopoiesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
3 June 2018
Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
3 June 2018
DNA binding specificities of Spi-1/PU.1 and Spi-B transcription factors and identification of a Spi-1/Spi-B binding site in the c-fes/c-fps promoter.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
3 June 2018
Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
27 November 2018
Regulation of B lymphocyte and macrophage development by graded expression of PU.1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
27 November 2018
Commitment to the monocytic lineage occurs in the absence of the transcription factor PU.1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
27 November 2018
Neutrophils deficient in PU.1 do not terminally differentiate or become functionally competent.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
27 November 2018
Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
27 November 2018
PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
27 November 2018
Differential expression of ets-1 and ets-2 proto-oncogenes during murine embryogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
27 November 2018
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125373
retrieved
27 November 2018
PU.1 exhibits partial functional redundancy with Spi-B, but not with Ets-1 or Elf-1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11980719
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Specificity within the ets family of transcription factors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11980719
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11980719
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11980719
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/EMBOJ/21.9.2220
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
PMCID
125373
0 references
PubMed ID
11980719
1 reference
stated in
PubMed
PubMed ID
11980719
retrieved
31 January 2017
ResearchGate publication ID
11388216
0 references
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