(Q28587546)

English

Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid

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scholarly article

1 reference

31 January 2017

Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid (English)

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31 January 2017

Alcohol dehydrogenase 1 (class I)

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GOA release 2020-03-11

Aldehyde dehydrogenase family 1, subfamily A1

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GOA release 2020-03-11

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based on heuristic

inferred from title

2

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author name string

Andrei Molotkov

1

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31 January 2017

language of work or name

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publication date

19 September 2003

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31 January 2017

Journal of Biological Chemistry

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31 January 2017

278

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31 January 2017

38

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31 January 2017

36085–36090

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31 January 2017

The role of vitamin A in mammalian reproduction and embryonic development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Retinoid activation of retinoic acid receptor but not retinoid X receptor is sufficient to rescue lethal defect in retinoic acid synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Teratogenicity of high vitamin A intake.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Catalytic efficiency of human alcohol dehydrogenases for retinol oxidation and retinal reduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Retinoids, omega-hydroxyfatty acids and cytotoxic aldehydes as physiological substrates, and H2-receptor antagonists as pharmacological inhibitors, of human class IV alcohol dehydrogenase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Kinetic mechanism of human class IV alcohol dehydrogenase functioning as retinol dehydrogenase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Identification and characterization of a stereospecific human enzyme that catalyzes 9-cis-retinol oxidation. A possible role in 9-cis-retinoic acid formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

The identification of a 9-cis retinol dehydrogenase in the mouse embryo reveals a pathway for synthesis of 9-cis retinoic acid.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Differential recognition of the free versus bound retinol by human microsomal retinol/sterol dehydrogenases: characterization of the holo-CRBP dehydrogenase activity of RoDH-4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Identification of mouse liver aldehyde dehydrogenases that catalyze the oxidation of retinaldehyde to retinoic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

A novel isoenzyme of aldehyde dehydrogenase specifically involved in the biosynthesis of 9-cis and all-trans retinoic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Aldehyde dehydrogenase 6, a cytosolic retinaldehyde dehydrogenase prominently expressed in sensory neuroepithelia during development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Kinetic analysis of mouse retinal dehydrogenase type-2 (RALDH2) for retinal substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Identification of the retinoic acid-inducible all-trans-retinoic acid 4-hydroxylase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Identification of human cytochrome P450 isoforms that contribute to all-trans-retinoic acid 4-hydroxylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Excessive vitamin A toxicity in mice genetically deficient in either alcohol dehydrogenase Adh1 or Adh3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Disruption of the 11-cis-retinol dehydrogenase gene leads to accumulation of cis-retinols and cis-retinyl esters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Embryonic retinoic acid synthesis is essential for early mouse post-implantation development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Stimulation of premature retinoic acid synthesis in Xenopus embryos following premature expression of aldehyde dehydrogenase ALDH1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

High levels of aldehyde dehydrogenase transcripts in the undifferentiated chick retina

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Differential regulation of the aldehyde dehydrogenase 1 gene in embryonic chick retina and liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Distinct functions for Aldh1 and Raldh2 in the control of ligand production for embryonic retinoid signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Filling the gap in vitamin A research. Molecular identification of an enzyme cleaving beta-carotene to retinal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Developmental changes in endogenous retinoids during pregnancy and embryogenesis in the mouse.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Plasma delivery of retinoic acid to tissues in the rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

The chemistry of rod vision.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Mechanisms of ethanol-drug-nutrition interactions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Retinol potentiates acetaminophen-induced hepatotoxicity in the mouse: mechanistic studies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Regional restriction of alcohol/retinol dehydrogenases along the mouse gastrointestinal epithelium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Aldehyde dehydrogenases and their role in carcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303709200

21 January 2018

Identifiers

10.1074/JBC.M303709200

1 reference

31 January 2017

1 reference

31 January 2017

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