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Methyl binding domain protein 2 mediates gamma-globin gene silencing in adult human betaYAC transgenic mice
scientific journal article
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scholarly article
1 reference
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PubMed
PubMed ID
16608912
retrieved
31 January 2017
title
Methyl binding domain protein 2 mediates gamma-globin gene silencing in adult human betaYAC transgenic mice
(English)
1 reference
stated in
PubMed
PubMed ID
16608912
retrieved
31 January 2017
main subject
Methyl-CpG binding domain protein 2
1 reference
stated in
GOA release 2020-03-11
gene silencing
1 reference
based on heuristic
inferred from title
author name string
Jeremy W. Rupon
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
16608912
retrieved
31 January 2017
Shou Zhen Wang
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
16608912
retrieved
31 January 2017
Karin Gaensler
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
16608912
retrieved
31 January 2017
Joyce Lloyd
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
16608912
retrieved
31 January 2017
Gordon D. Ginder
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
16608912
retrieved
31 January 2017
language of work or name
English
0 references
publication date
25 April 2006
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PubMed
PubMed ID
16608912
retrieved
31 January 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
PubMed
PubMed ID
16608912
retrieved
31 January 2017
volume
103
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stated in
PubMed
PubMed ID
16608912
retrieved
31 January 2017
issue
17
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stated in
PubMed
PubMed ID
16608912
retrieved
31 January 2017
page(s)
6617–6622
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stated in
PubMed
PubMed ID
16608912
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31 January 2017
cites work
Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
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17 March 2017
Kaiso is a genome-wide repressor of transcription that is essential for amphibian development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
17 March 2017
Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
17 March 2017
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
17 March 2017
The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
17 March 2017
Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
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17 March 2017
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
17 March 2017
MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
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17 March 2017
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
17 March 2017
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
17 March 2017
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
17 March 2017
Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
17 March 2017
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
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17 March 2017
Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
17 March 2017
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
7 April 2017
Histone H3 lysine 4 methylation patterns in higher eukaryotic genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
7 April 2017
Kaiso-deficient mice show resistance to intestinal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5'HS3 deletion mutations: implication for LCR chromatin architecture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
A GATA factor mediates cell type-restricted induction of HLA-E gene transcription by gamma interferon
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
Gene silencing quantitatively controls the function of a developmental trans-activator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
The p120(ctn)-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
Methylation of the minimal promoter of an embryonic globin gene silences transcription in primary erythroid cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
CpG islands and genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
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29 September 2017
Number of CpG islands and genes in human and mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
Tissue-specific DNA methylation in a cluster of rabbit beta-like globin genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
DNA methylation in the human γδβ-globin locus in erythroid and nonerythroid tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
DNA methylation and regulation of the human beta-globin-like genes in mouse erythroleukemia cells containing human chromosome 11
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
Activation of a chicken embryonic globin gene in adult erythroid cells by 5-azacytidine and sodium butyrate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
5-Azacytidine acts directly on both erythroid precursors and progenitors to increase production of fetal hemoglobin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
29 September 2017
Methylation of promoter proximal-transcribed sequences of an embryonic globin gene inhibits transcription in primary erythroid cells and promotes formation of a cell type-specific methyl cytosine binding complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
3 June 2018
The human beta globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
3 June 2018
alpha-Amino butyric acid cannot reactivate the silenced gamma gene of the beta locus YAC transgenic mouse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
3 June 2018
Arabinosylcytosine Induces Fetal Hemoglobin in Baboons by Perturbing Erythroid Cell Differentiation Kinetics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
3 June 2018
Stimulation of F-cell production in patients with sickle-cell anemia treated with cytarabine or hydroxyurea
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
3 June 2018
Regulation of human fetal and adult globin genes in mouse erythroleukemia cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
3 June 2018
Specific DNA methylation sites in the vicinity of the chicken beta-globin genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
3 June 2018
Methyl-CpG-binding domain protein-2 mediates transcriptional repression associated with hypermethylated GSTP1 CpG islands in MCF-7 breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1458932
retrieved
27 November 2018
Effect of phenylhydrazine-induced hemolytic anemia on nuclear RNA polymerase activity of the mouse spleen
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16608912
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β+Thalassemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16608912
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16608912
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Augmentation of Fetal-Hemoglobin Production in Anemic Monkeys by Hydroxyurea
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16608912
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA methylation: a secondary event in globin gene switching?
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16608912
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Butyrate induces selective transcriptional activation of a hypomethylated embryonic globin gene in adult erythroid cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16608912
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Metabolic persistence of fetal hemoglobin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16608912
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
2-deoxy 5-azacytidine and fetal hemoglobin induction in sickle cell anemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16608912
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.0509322103
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2340344
ADS bibcode
2006PNAS..103.6617R
0 references
OpenCitations bibliographic resource ID
2340344
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2340344
PMCID
1458932
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2340344
PubMed ID
16608912
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2340344
ResearchGate publication ID
7171076
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