(Q28590697)

31 January 2017

title

DNA damage-induced G2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphatase (English)

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Cyclin-dependent kinase 1

31 January 2017

main subject

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Ataxia telangiectasia mutated

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Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

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Serine/threonine-protein kinase ATR

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Mitogen-activated protein kinase 14

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Protein tyrosine phosphatase, non-receptor type 11

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Cell division cycle 25C

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author name string

Liangping Yuan

series ordinal

1

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31 January 2017

Wen-Mei Yu

series ordinal

2

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31 January 2017

Cheng-Kui Qu

series ordinal

3

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31 January 2017

language of work or name

English

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publication date

31 October 2003

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

278

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31 January 2017

issue

44

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31 January 2017

page(s)

42812–42820

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The DNA damage response: putting checkpoints in perspective

31 January 2017

cites work

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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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Radiation-induced cell cycle arrest compromised by p21 deficiency

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Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

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Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

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Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

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Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

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Requirement for MAPK activation for normal mitotic progression in Xenopus egg extracts.

21 January 2018

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Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts

21 January 2018

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ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

21 January 2018

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Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

21 January 2018

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Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

21 January 2018

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21 January 2018

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Role of the SHP-2 tyrosine phosphatase in cytokine-induced signaling and cellular response

21 January 2018

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Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression

21 January 2018

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21 January 2018

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21 January 2018

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A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development

21 January 2018

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The Shp-2 tyrosine phosphatase has opposite effects in mediating the activation of extracellular signal-regulated and c-Jun NH2-terminal mitogen-activated protein kinases

21 January 2018

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Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion

21 January 2018

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Genetic evidence that Shp-2 tyrosine phosphatase is a signal enhancer of the epidermal growth factor receptor in mammals

21 January 2018

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Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response

21 January 2018

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Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity

21 January 2018

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Modulation of the nuclear factor kappa B pathway by Shp-2 tyrosine phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumor necrosis factor

21 January 2018

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21 January 2018

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21 January 2018

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Requirement for ERK activation in cisplatin-induced apoptosis

21 January 2018

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21 January 2018

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Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line

21 January 2018

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Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells

21 January 2018

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Protective role for c-Jun in the cellular response to DNA damage

21 January 2018

1 reference

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Insulin-like growth factor-I (IGF-I) receptor activation rescues UV-damaged cells through a p38 signaling pathway. Potential role of the IGF-I receptor in DNA repair

21 January 2018

1 reference

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Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M305075200

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31 January 2017

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