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ATR disruption leads to chromosomal fragmentation and early embryonic lethality
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
10691732
retrieved
31 January 2017
title
ATR disruption leads to chromosomal fragmentation and early embryonic lethality
(English)
1 reference
stated in
PubMed
PubMed ID
10691732
retrieved
31 January 2017
main subject
Serine/threonine-protein kinase ATR
1 reference
stated in
GOA release 2020-03-11
author name string
E. J. Brown
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
10691732
retrieved
31 January 2017
D. Baltimore
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
10691732
retrieved
31 January 2017
publication date
15 February 2000
1 reference
stated in
PubMed
PubMed ID
10691732
retrieved
31 January 2017
published in
Genes & Development
1 reference
stated in
PubMed
PubMed ID
10691732
retrieved
31 January 2017
volume
14
1 reference
stated in
PubMed
PubMed ID
10691732
retrieved
31 January 2017
page(s)
397–402
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stated in
PubMed
PubMed ID
10691732
retrieved
31 January 2017
issue
4
1 reference
stated in
PubMed
PubMed ID
10691732
retrieved
31 January 2017
cites work
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
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14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage
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Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
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A role for ATR in the DNA damage-induced phosphorylation of p53
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PubMed Central
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17 March 2017
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
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PubMed Central
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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
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Involvement of Brca2 in DNA repair
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Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
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17 March 2017
Brca2 is required for embryonic cellular proliferation in the mouse
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PubMed Central
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17 March 2017
Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
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The Schizosaccharomyces pombe rad3 checkpoint gene
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PubMed Central
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cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein
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Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase
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Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
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PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints
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Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
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The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse
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Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
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29 September 2017
Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control
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PubMed Central
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29 September 2017
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
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PubMed Central
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29 September 2017
Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints
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PubMed Central
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29 September 2017
The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.
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Caspase activity is required for commitment to Fas-mediated apoptosis.
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3 June 2018
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.
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PubMed Central
reference URL
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27 November 2018
Checkpoint on the nuclear frontier
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PubMed Central
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27 November 2018
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27 November 2018
The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene
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PubMed Central
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27 November 2018
Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10691732
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10691732
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10691732
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA damage and checkpoint pathways: molecular anatomy and interactions with repair
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10691732
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Checkpoints on the road to mitosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10691732
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Atm haploinsufficiency results in increased sensitivity to sublethal doses of ionizing radiation in mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10691732
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
OpenCitations bibliographic resource ID
1545602
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1545602
PMCID
316378
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1545602
PubMed ID
10691732
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1545602
ResearchGate publication ID
12623312
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