(Q34453891)

2 August 2017

ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage (English)

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2 August 2017

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M I Aladjem

1

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2 August 2017

B T Spike

2

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2 August 2017

L W Rodewald

3

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2 August 2017

T J Hope

4

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2 August 2017

M Klemm

5

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2 August 2017

R Jaenisch

6

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2 August 2017

G M Wahl

7

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2 August 2017

language of work or name

English

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publication date

1 January 1998

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2 August 2017

11

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inferred from page(s)

published in

Current Biology

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2 August 2017

8

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2 August 2017

145-155

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2 August 2017

3

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Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Checkpoints: controls that ensure the order of cell cycle events

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Fission yeast genes involved in coupling mitosis to completion of DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Cell cycle control, DNA repair and initiation of carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

p53-dependent apoptosis suppresses radiation-induced teratogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Cell cycle control and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

p53; from inductive signal to cellular effect

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Signalling to p53: where does it all start?

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

A p53-dependent mouse spindle checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Derivation of embryonic stem cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

The mdm-2 gene is induced in response to UV light in a p53-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

mdm2 expression is induced by wild type p53 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Development and characterization of recombinant adenoviruses encoding human p53 for gene therapy of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

The role of DNA fragmentation in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Developmental control of cell cycle regulators: a fly's perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

The events of the midblastula transition in Xenopus are regulated by changes in the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Essential role for p53-mediated transcription in E1A-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Inhibition of apoptosis by the retinoblastoma gene product.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

1 reference

7 January 2021

Cyclin synthesis drives the early embryonic cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Regulation of the Cellular p53 Tumor Antigen in Teratocarcinoma Cells and Their Differentiated Progeny

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

The phosphoprotein p53 is down-regulated post-transcriptionally during embryogenesis in vertebrates

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Post-Translational Regulation of the 54K Cellular Tumor Antigen in Normal and Transformed Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2898%2970061-2

7 January 2021

10.1016/S0960-9822(98)70061-2

Identifiers

DOI

1 reference

2 August 2017

1 reference