(Q41345451)

29 September 2017

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title

p53; from inductive signal to cellular effect (English)

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29 September 2017

Hansen R

1

1 reference

PubMed ID

9024633

29 September 2017

Oren M

series ordinal

2

1 reference

PubMed ID

9024633

29 September 2017

language of work or name

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1 February 1997

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Current Opinion in Genetics & Development

29 September 2017

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29 September 2017

7

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29 September 2017

1

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29 September 2017

46-51

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29 September 2017

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

p53 expression is required for thymocyte apoptosis induced by adenosine deaminase deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Translational regulation of human p53 gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Negative feedback regulation of wild-type p53 biosynthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Small peptides activate the latent sequence-specific DNA binding function of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Physical and functional interactions between p53 and cell cycle co-operating transcription factors, E2F1 and DP1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

p53 stimulates transcription from the human transforming growth factor alpha promoter: a potential growth-stimulatory role for p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Wild-type human p53 transactivates the human proliferating cell nuclear antigen promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: activation of the vertebrate homologue of the drosophila seven in absentia gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Essential role for p53-mediated transcription in E1A-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Genetic determinants of p53-induced apoptosis and growth arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Increased activity of p53 in senescing fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

A subset of p53-deficient embryos exhibit exencephaly

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

High-frequency developmental abnormalities in p53-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

p53-dependent apoptosis suppresses radiation-induced teratogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

p53 modulation of TFIIH-associated nucleotide excision repair activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

p53 deficiency does not affect the accumulation of point mutations in a transgene target

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

p53 Protein exhibits 3'-to-5' exonuclease activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

Abnormal centrosome amplification in the absence of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

A p53-dependent mouse spindle checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2897%2980108-6

7 January 2021

10.1016/S0959-437X(97)80108-6

Identifiers

DOI

1 reference

29 September 2017

1 reference

PubMed ID

9024633