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p53 Protein exhibits 3'-to-5' exonuclease activity
scientific article published on 01 June 1996
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
title
p53 Protein exhibits 3'-to-5' exonuclease activity
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
author name string
T Mummenbrauer
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
F Janus
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
B Müller
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
L Wiesmüller
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
W Deppert
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
F Grosse
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
language of work or name
English
0 references
publication date
1 June 1996
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
published in
Cell
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
volume
85
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
issue
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
page(s)
1089-1099
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
cites work
p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutator phenotypes in human colorectal carcinoma cell lines
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Genetic steps in colorectal cancer.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumour suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of DNA replication factor RPA by p53.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Definition of a consensus binding site for p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
WAF1, a potential mediator of p53 tumor suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of mismatch repair genes and their role in the development of cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A DNA binding domain is contained in the C-terminus of wild type p53 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and characterization of DNA sequences that are specifically bound by wild-type p53 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53: a glimpse at the puppet behind the shadow play
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transcriptionally active DNA-binding site for human p53 protein complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Terminal deoxyribonucleotidyl transferase (EC 2.7.7.31).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical implications of the p53 tumor-suppressor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle control and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Processivity of the DNA polymerase alpha-primase complex from calf thymus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 mutations in human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allosteric activation of latent p53 tetramers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the specific DNA binding function of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of p53 as a sequence-specific DNA-binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic forms of p53 inhibit p53-regulated gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer. p53, guardian of the genome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How p53 suppresses cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA mismatch correction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mismatch repair, genetic stability, and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and function of the multifunctional DNA-repair enzyme exonuclease III
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative feedback regulation of wild-type p53 biosynthesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunoaffinity-purified DNA polymerase alpha displays novel properties.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-catalyzed annealing of complementary single-stranded nucleic acids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypermutability and mismatch repair deficiency in RER+ tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Carcinogenesis. Missing mismatch repair.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian p53 can function as a transcription factor in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of T7 RNA polymerase to direct expression of cloned genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The double-strand-break repair model for recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 function and dysfunction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Eukaryotic DNA polymerases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 domains: identification and characterization of two autonomous DNA-binding regions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981309-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(00)81309-4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
PubMed publication ID
8674115
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8674115
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8674115%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
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