(Q28593439)

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Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction

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scholarly article

1 reference

Europe PubMed Central

6 July 2017

Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction (English)

1 reference

Europe PubMed Central

6 July 2017

Ubiquitin protein ligase E3A

1 reference

GOA release 2020-03-11

Bert W. O'Malley

7

object named as

Bert W O'Malley

1 reference

Europe PubMed Central

6 July 2017

author name string

Zafar Nawaz

4

1 reference

Europe PubMed Central

6 July 2017

Yong-Hui Jiang

5

1 reference

Europe PubMed Central

6 July 2017

Carolyn L Smith

1

1 reference

Europe PubMed Central

6 July 2017

Darryll G DeVera

2

1 reference

Europe PubMed Central

6 July 2017

Dolores J Lamb

3

1 reference

Europe PubMed Central

6 July 2017

Arthur L Beaudet

6

1 reference

Europe PubMed Central

6 July 2017

language of work or name

0 references

publication date

1 January 2002

1 reference

Europe PubMed Central

6 July 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

6 July 2017

22

1 reference

Europe PubMed Central

6 July 2017

525-535

1 reference

Europe PubMed Central

6 July 2017

2

1 reference

Europe PubMed Central

6 July 2017

The nuclear receptor co-repressor nrip1 (RIP140) is essential for female fertility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Extensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

The coregulator exchange in transcriptional functions of nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Regulation of transcription by a protein methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Generation and reproductive phenotypes of mice lacking estrogen receptor beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

E3-ubiquitin ligase/E6-AP links multicopy maintenance protein 7 to the ubiquitination pathway by a novel motif, the L2G box

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Steroid receptor coactivator-1 is a histone acetyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

UBE3A/E6-AP mutations cause Angelman syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

The transcriptional coactivators p300 and CBP are histone acetyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

17 March 2017

Nuclear receptor coregulators: cellular and molecular biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

7 April 2017

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

7 April 2017

Regulation of somatic growth by the p160 coactivator p/CIP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Mammary gland development and tumorigenesis in estrogen receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Nuclear hormone receptor coregulators in action: diversity for shared tasks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Ubiquitin-mediated degradation of active Src tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Proteasome-mediated proteolysis of estrogen receptor: a novel component in autologous down-regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Impairment of spermatogenesis in mice lacking a functional aromatase (cyp 19) gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Genetics of Angelman syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Proteasome-dependent degradation of the human estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Abnormal skeletal patterning in embryos lacking a single Cbp allele: a partial similarity with Rubinstein-Taybi syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

The E6-Ap ubiquitin-protein ligase (UBE3A) gene is localized within a narrowed Angelman syndrome critical region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Angelman syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Science behind total androgen blockade: from gene to combination therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Imprinting analysis of three genes in the Prader-Willi/Angelman region: SNRPN, E6-associated protein, and PAR-2 (D15S225E).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

The 'happy puppet' syndrome of Angelman: review of the clinical features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Normal and abnormal follicular growth in mouse, rat and human ovaries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

29 September 2017

Morphologic changes in efferent ductules and epididymis in estrogen receptor-alpha knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

3 June 2018

Implication of proteasome in estrogen receptor degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

3 June 2018

Characterization of the interactions of human papillomavirus type 16 E6 with p53 and E6-associated protein in insect and human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

3 June 2018

Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

3 June 2018

Hormone dependence of mammary tumors induced in rats by intraperitoneal NMU injection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

3 June 2018

Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

3 June 2018

The use of zona-free animal ova as a test-system for the assessment of the fertilizing capacity of human spermatozoa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

3 June 2018

Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

27 November 2018

The Angelman syndrome candidate gene, UBE3A/E6-AP, is imprinted in brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

27 November 2018

Imprinting of the Angelman syndrome gene, UBE3A, is restricted to brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

27 November 2018

Relative distribution of estrogen and progesterone receptors among the epithelial, adipose, and connective tissue components of the normal mammary gland.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139730

27 November 2018

Mammary gland development is mediated by both stromal and epithelial progesterone receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for enhanced ubiquitin-mediated proteolysis of the chicken progesterone receptor by progesterone

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of various doses of testosterone propionate on intratesticular and plasma testosterone levels and maintenance of spermatogenesis in adult hypophysectomized rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between prolactin and androgens in the accessory sex organs of male mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgens modulate epidermal growth factor receptor levels in the rat ventral prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative cytological studies of spermatogenesis in intact and hypophysectomized rats: identification of androgen-dependent stages

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ontogeny and cellular distribution of estrogen receptors in normal mouse mammary gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/11756548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.22.2.525-535.2002

1 reference

Europe PubMed Central

6 July 2017

1 reference

Europe PubMed Central

6 July 2017

1 reference

Europe PubMed Central

6 July 2017

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