(Q28593787)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

GOA release 2020-03-11

author

Karl E Kadler

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

author name string

Yinhui Lu

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Manuel Koch

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Joy Lincoln

7

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Agata K Levay

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Jacqueline D Peacock

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Robert B Hinton

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

publication date

18 September 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

103

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

issue

9

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

page(s)

948-956

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

Heart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

14 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Mutations in NOTCH1 cause aortic valve disease

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

FGF acts directly on the somitic tendon progenitors through the Ets transcription factors Pea3 and Erm to regulate scleraxis expression

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Interaction between cell and extracellular matrix in heart disease: multiple roles of tenascin-C in tissue remodeling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Sox9 is required for cartilage formation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Scleraxis positively regulates the expression of tenomodulin, a differentiation marker of tenocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

A look between the cardiomyocytes: the extracellular matrix in heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Mechanisms of disease: pathologic structural remodeling is more than adaptive hypertrophy in hypertensive heart disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

The extracellular matrix and the cytoskeleton in heart hypertrophy and failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Cell biology of cardiac cushion development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Heart valve development: endothelial cell signaling and differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Bicuspid aortic valve is heritable

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Form and function of developing heart valves: coordination by extracellular matrix and growth factor signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Tbx20 regulation of endocardial cushion cell proliferation and extracellular matrix gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Generation of transgenic tendon reporters, ScxGFP and ScxAP, using regulatory elements of the scleraxis gene.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

BMP and FGF regulatory pathways in semilunar valve precursor cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

BMP and FGF regulatory pathways control cell lineage diversification of heart valve precursor cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Feedback interactions between MKP3 and ERK MAP kinase control scleraxis expression and the specification of rib progenitors in the developing chick somite

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Dynamic and reversible changes of interstitial cell phenotype during remodeling of cardiac valves.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Lineage and morphogenetic analysis of the cardiac valves.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Molecular markers of cardiac endocardial cushion development.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Fgf4 positively regulates scleraxis and tenascin expression in chick limb tendons

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Type XII and XIV collagens mediate interactions between banded collagen fibers in vitro and may modulate extracellular matrix deformability.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743952

Expression of type XIV collagen in developing chicken tendons: association with assembly and growth of collagen fibrils

27 November 2018

1 reference

12 December 2020

The roles of types XII and XIV collagen in fibrillogenesis and matrix assembly in the developing cornea

1 reference

12 December 2020

The epidemiology of valvular heart diseases: the problem is growing

1 reference

12 December 2020

Activation of matrix metalloproteinases in the failing human heart: breaking the tie that binds

1 reference

12 December 2020

Extracellular Matrix Remodeling and Organization in Developing and Diseased Aortic Valves

1 reference

12 December 2020

Active Negative Control of Collagen Fibrillogenesisin Vivo

1 reference

12 December 2020

10.1161/CIRCRESAHA.108.177238

Identifiers

DOI

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18802027%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

2 references

31 January 2017