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CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion
scientific journal article
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scholarly article
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PubMed
PubMed ID
22531781
retrieved
31 January 2017
title
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion
(English)
1 reference
stated in
PubMed
PubMed ID
22531781
retrieved
31 January 2017
main subject
CTS telomere maintenance complex component 1
1 reference
stated in
GOA release 2020-03-11
TATA element modulatory factor 1
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stated in
GOA release 2020-03-11
author name string
Peili Gu
series ordinal
1
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PubMed
PubMed ID
22531781
retrieved
31 January 2017
Jin-Na Min
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2
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stated in
PubMed
PubMed ID
22531781
retrieved
31 January 2017
Yang Wang
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
22531781
retrieved
31 January 2017
Chenhui Huang
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
22531781
retrieved
31 January 2017
Tao Peng
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
22531781
retrieved
31 January 2017
Weihang Chai
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
22531781
retrieved
31 January 2017
Sandy Chang
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7
1 reference
stated in
PubMed
PubMed ID
22531781
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31 January 2017
language of work or name
English
0 references
publication date
16 May 2012
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PubMed
PubMed ID
22531781
retrieved
31 January 2017
published in
The EMBO Journal
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stated in
PubMed
PubMed ID
22531781
retrieved
31 January 2017
volume
31
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PubMed
PubMed ID
22531781
retrieved
31 January 2017
issue
10
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stated in
PubMed
PubMed ID
22531781
retrieved
31 January 2017
page(s)
2309–2321
1 reference
stated in
PubMed
PubMed ID
22531781
retrieved
31 January 2017
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Europe PubMed Central
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11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3364752/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Telomere protection by TPP1 is mediated by POT1a and POT1b
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
A DNA polymerase-{alpha}⋅primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
RPA-like proteins mediate yeast telomere function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Chromosome end protection plasticity revealed by Stn1p and Ten1p bypass of Cdc13p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Homologous recombination generates T-loop-sized deletions at human telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
17 March 2017
Mutations in CTC1, encoding the CTS telomere maintenance complex component 1, cause cerebroretinal microangiopathy with calcifications and cysts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
RPA and POT1: friends or foes at telomeres?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Xenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Essential roles for Pot1b in HSC self-renewal and survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Mammalian 5' C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Telomere biology and telomere diseases: implications for practice and research
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Telomere replication: poised but puzzling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
CST meets shelterin to keep telomeres in check
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
p53 prevents entry into mitosis with uncapped telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Replisome structure and conformational dynamics underlie fork progression past obstacles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Unusual telomeric DNAs in human telomerase-negative immortalized cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Engineered telomere degradation models dyskeratosis congenita
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Telomere dysfunction and tumour suppression: the senescence connection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
DNA strand break repair and human genetic disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
How telomeres are replicated
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Prediction of multiple tandem OB-fold domains in telomere end-binding proteins Pot1 and Cdc13.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Coats' plus: a progressive familial syndrome of bilateral Coats' disease, characteristic cerebral calcification, leukoencephalopathy, slow pre- and post-natal linear growth and defects of bone marrow and integument.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
Cdc13 both positively and negatively regulates telomere replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
A familial syndrome with coats' reaction retinal angiomas, hair and nail defects and intracranial calcification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
29 September 2017
The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
3 June 2018
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
3 June 2018
Mec1 and Rad53 inhibit formation of single-stranded DNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
3 June 2018
The mechanism of action of an accessory protein for DNA polymerase alpha/primase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364752
retrieved
3 June 2018
Connecting complex disorders through biology.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2012.96
retrieved
21 January 2018
Semi-conservative DNA replication through telomeres requires Taz1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2012.96
retrieved
21 January 2018
Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22531781
retrieved
12 December 2020
based on heuristic
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Identifiers
DOI
10.1038/EMBOJ.2012.96
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1105979
OpenCitations bibliographic resource ID
1105979
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1105979
PMCID
3364752
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1105979
PubMed ID
22531781
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1105979
ResearchGate publication ID
224835486
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