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Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
17687332
retrieved
25 July 2017
title
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
17687332
retrieved
25 July 2017
author
Titia de Lange
object named as
Titia de Lange
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2
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Eros Lazzerini Denchi
object named as
Eros Lazzerini Denchi
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1
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language of work or name
English
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publication date
8 August 2007
1 reference
stated in
Europe PubMed Central
PubMed ID
17687332
retrieved
25 July 2017
published in
Nature
1 reference
stated in
Europe PubMed Central
PubMed ID
17687332
retrieved
25 July 2017
volume
448
1 reference
stated in
Europe PubMed Central
PubMed ID
17687332
retrieved
25 July 2017
page(s)
1068-1071
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stated in
Europe PubMed Central
PubMed ID
17687332
retrieved
25 July 2017
issue
7157
1 reference
stated in
Europe PubMed Central
PubMed ID
17687332
retrieved
25 July 2017
exact match
https://scigraph.springernature.com/pub.10.1038/nature06065
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cites work
Shelterin: the protein complex that shapes and safeguards human telomeres
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A DNA damage checkpoint response in telomere-initiated senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage foci at dysfunctional telomeres
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Different telomere damage signaling pathways in human and mouse cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atm-deficient mice: a paradigm of ataxia telangiectasia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDC1 accelerates nonhomologous end-joining of dysfunctional telomeres
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The maintenance and masking of chromosome termini
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere protection by mammalian Pot1 requires interaction with Tpp1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATR and ATRIP: partners in checkpoint signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
POT1 as a terminal transducer of TRF1 telomere length control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian telomeres end in a large duplex loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Harmonising the response to DSBs: a new string in the ATM bow.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NATURE06065
1 reference
stated in
Europe PubMed Central
PubMed ID
17687332
retrieved
25 July 2017
Dimensions Publication ID
1043267773
0 references
PubMed ID
17687332
1 reference
stated in
Europe PubMed Central
PubMed ID
17687332
retrieved
25 July 2017
ResearchGate publication ID
6152900
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