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Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
14608355
retrieved
31 January 2017
title
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice
(English)
1 reference
stated in
PubMed
PubMed ID
14608355
retrieved
31 January 2017
main subject
pathology
0 references
Endothelial PAS domain protein 1
1 reference
stated in
GOA release 2020-03-11
reactive oxygen species
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based on heuristic
inferred from title
oxygen
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based on heuristic
inferred from title
author
Liang-Jun Yan
object named as
Liang-Jun Yan
series ordinal
6
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author name string
Marzia Scortegagna
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1
1 reference
stated in
PubMed
PubMed ID
14608355
retrieved
31 January 2017
Kan Ding
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
14608355
retrieved
31 January 2017
Yavuz Oktay
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3
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PubMed
PubMed ID
14608355
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31 January 2017
Arti Gaur
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4
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PubMed
PubMed ID
14608355
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31 January 2017
Frederick Thurmond
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5
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PubMed
PubMed ID
14608355
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31 January 2017
Brett T. Marck
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7
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PubMed
PubMed ID
14608355
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31 January 2017
Alvin M. Matsumoto
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8
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PubMed
PubMed ID
14608355
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31 January 2017
John M. Shelton
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9
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PubMed
PubMed ID
14608355
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James A. Richardson
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10
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PubMed
PubMed ID
14608355
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Michael J. Bennett
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11
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PubMed
PubMed ID
14608355
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31 January 2017
Joseph A. Garcia
series ordinal
12
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PubMed
PubMed ID
14608355
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31 January 2017
language of work or name
English
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publication date
1 December 2003
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PubMed
PubMed ID
14608355
retrieved
31 January 2017
published in
Nature Genetics
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stated in
PubMed
PubMed ID
14608355
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31 January 2017
volume
35
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PubMed
PubMed ID
14608355
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31 January 2017
page(s)
331–340
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PubMed
PubMed ID
14608355
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31 January 2017
issue
4
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PubMed
PubMed ID
14608355
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31 January 2017
cites work
Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
inferred from DOI database lookup
A redox mechanism controls differential DNA binding activities of hypoxia-inducible factor (HIF) 1alpha and the HIF-like factor.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
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inferred from DOI database lookup
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
inferred from DOI database lookup
HIF-1 alpha is required for solid tumor formation and embryonic vascularization.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
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inferred from DOI database lookup
The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
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The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
inferred from DOI database lookup
The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ragged red fibers in normal aging and inflammatory myopathy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial diseases in man and mouse
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Measurement of superoxide radical and hydrogen peroxide production in isolated cells and subcellular organelles
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of stress response genes GADD153, c-jun, and heme oxygenase-1 in H2O2- and O2-resistant fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional induction of metallothionein-I and -II genes in the livers of Cu,Zn-superoxide dismutase knockout mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor-alpha selectively induces MnSOD expression via mitochondria-to-nucleus signaling, whereas interleukin-1beta utilizes an alternative pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
inferred from DOI database lookup
Peroxynitrite modulates MnSOD gene expression in lung epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic modification of prenatal lethality and dilated cardiomyopathy in Mn superoxide dismutase mutant mice
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Crossref
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https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
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inferred from DOI database lookup
A quantitative genetic analysis of tissue-specific catalase activity in Mus musculus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue-specific developmental regulation of superoxide dismutase (SOD-1 and SOD-2) activities in genetic strains of mice.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the murine gene encoding Aop2 (antioxidant protein 2) and identification of two highly related genes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial respiratory-chain diseases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Primary defect of juvenile visceral steatosis (jvs) mouse with systemic carnitine deficiency is probably in renal carnitine transport system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial abnormalities of muscle tissue in mice with juvenile visceral steatosis associated with systemic carnitine deficiency
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial abnormalities in a murine model of primary carnitine deficiency. Systemic pathology and trial of replacement therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antioxidant changes in the hypertrophied heart due to energy metabolic disorder
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial disease in mouse results in increased oxidative stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peroxynitrite inactivation of tyrosine hydroxylase: mediation by sulfhydryl oxidation, not tyrosine nitration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peroxynitrite-mediated inhibition of DOPA synthesis in PC12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dopamine- and L-beta-3,4-dihydroxyphenylalanine hydrochloride (L-Dopa)-induced cytotoxicity towards catecholaminergic neuroblastoma SH-SY5Y cells. Effects of oxidative stress and antioxidative factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hyperglycemic switch from mitochondrial nitric oxide to superoxide production in endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lactate and PO2 modulate superoxide anion production in bovine cardiac myocytes: potential role of NADH oxidase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxic modulation of manganese superoxide dismutase promoter activity and gene expression in lung epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription regulation of human manganese superoxide dismutase gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of gene expression by reactive oxygen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxygen sensing and molecular adaptation to hypoxia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNG1266
retrieved
7 January 2021
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Identifiers
DOI
10.1038/NG1266
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
413110
OpenCitations bibliographic resource ID
413110
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
413110
PubMed ID
14608355
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
413110
ResearchGate publication ID
9017525
0 references
Springer Nature article ID
10.1038/ng1266
0 references
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