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Activation of c-Jun N-terminal kinase 1 by UV irradiation is inhibited by wortmannin without affecting c-iun expression
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scholarly article
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PubMed
PubMed ID
10022864
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3 February 2017
title
Activation of c-Jun N-terminal kinase 1 by UV irradiation is inhibited by wortmannin without affecting c-iun expression
(English)
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PubMed
PubMed ID
10022864
retrieved
3 February 2017
author name string
G. Fritz
series ordinal
1
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PubMed
PubMed ID
10022864
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3 February 2017
B. Kaina
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2
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PubMed
PubMed ID
10022864
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3 February 2017
language of work or name
English
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publication date
1 March 1999
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PubMed
PubMed ID
10022864
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3 February 2017
published in
Molecular and Cellular Biology
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PubMed
PubMed ID
10022864
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3 February 2017
volume
19
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PubMed
PubMed ID
10022864
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3 February 2017
page(s)
1768–1774
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stated in
PubMed
PubMed ID
10022864
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3 February 2017
issue
3
1 reference
stated in
PubMed
PubMed ID
10022864
retrieved
3 February 2017
cites work
Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli
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PubMed Central
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Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3
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17 March 2017
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase
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PubMed Central
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17 March 2017
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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17 March 2017
Transcription factor ATF2 regulation by the JNK signal transduction pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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17 March 2017
ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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17 March 2017
ATF-2 contains a phosphorylation-dependent transcriptional activation domain
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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17 March 2017
The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
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17 March 2017
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
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17 March 2017
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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7 April 2017
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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7 April 2017
Proteinase inhibitors I and II from potatoes specifically block UV-induced activator protein-1 activation through a pathway that is independent of extracellular signal-regulated kinases, c-Jun N-terminal kinases, and P38 kinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
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29 September 2017
The Ras farnesylation inhibitor BZA-5B increases the resistance to cisplatin in a human melanoma cell line
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
Contribution of O6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines
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29 September 2017
Fos is an essential component of the mammalian UV response
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
Ionizing radiation regulates expression of the c-jun protooncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
Phosphorylation of c-jun mediated by MAP kinases.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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29 September 2017
A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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3 June 2018
Three distinct signalling responses by murine fibroblasts to genotoxic stress
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
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3 June 2018
Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
retrieved
3 June 2018
PI 3-kinase activation is required for insulin stimulation of glucose transport into L6 myotubes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
retrieved
3 June 2018
c-Fos is involved in the cellular defence against the genotoxic effect of UV radiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
retrieved
3 June 2018
PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
retrieved
3 June 2018
The ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA damaging treatments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
retrieved
3 June 2018
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
retrieved
3 June 2018
Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentiation, AP-1 activity and tumorigenicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
retrieved
3 June 2018
Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
retrieved
27 November 2018
Binding of promoter-associated AP-1 is not altered during induction and subsequent repression of the c-jun promoter by TPA and UV irradiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83970
retrieved
27 November 2018
Intracellular signalling. PI 3-kinase puts GTP on the Rac
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10022864
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Three paths to stress relief
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10022864
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ultraviolet B-induced activated protein-1 activation does not require epidermal growth factor receptor but is blocked by a dominant negative PKClambda/iota
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10022864
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High-dose selection with mafosfamide results in sensitivity to DNA cross-linking agents: characterization of hypersensitive cell lines
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10022864
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A general role for c-Fos in cellular protection against DNA-damaging carcinogens and cytostatic drugs
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10022864
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effect of wortmannin and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) on N-formyl-methionyl-leucyl-phenylalanine-induced phospholipase D activation in differentiated HL60 cells: possible involvement of phosphatidylinositol 3-kinase in
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10022864
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10022864
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10022864
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Involvement of growth factor receptors in the mammalian UVC response
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10022864
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.19.3.1768
0 references
PMCID
83970
0 references
PubMed ID
10022864
1 reference
stated in
PubMed
PubMed ID
10022864
retrieved
3 February 2017
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