(Q28609748)

3 February 2017

title

Loop 6 of RhoA confers specificity for effector binding, stress fiber formation, and cellular transformation (English)

1 reference

3 February 2017

H. Zong

1

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3 February 2017

N. Raman

2

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3 February 2017

L. A. Mickelson-Young

3

1 reference

3 February 2017

S. J. Atkinson

4

1 reference

3 February 2017

L. A. Quilliam

5

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3 February 2017

language of work or name

English

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publication date

19 February 1999

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Journal of Biological Chemistry

3 February 2017

published in

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3 February 2017

volume

274

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3 February 2017

issue

8

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3 February 2017

page(s)

4551–4560

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Rho GTPases and the actin cytoskeleton

3 February 2017

cites work

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The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

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Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling

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An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

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Effector domain mutations dissociate p21ras effector function and GTPase-activating protein interaction

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Multiple Ras functions can contribute to mammalian cell transformation

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Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

21 January 2018

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Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

21 January 2018

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Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

21 January 2018

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Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

21 January 2018

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RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase

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The small GTPase Rho: cellular functions and signal transduction

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Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family

21 January 2018

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The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization

21 January 2018

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Isolation and characterization of a structural homologue of human PRK2 from rat liver. Distinguishing substrate and lipid activator specificities

21 January 2018

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Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis. Identification by a novel, small pool expression cloning strategy

21 January 2018

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Rho effectors and reorganization of actin cytoskeleton

21 January 2018

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Construction and applications of a highly transmissible murine retrovirus shuttle vector

21 January 2018

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Purification of recombinant Rho/Rac/G25K from Escherichia coli.

21 January 2018

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Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins

21 January 2018

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Biological assays for Ras transformation

21 January 2018

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Multiple interactions of PRK1 with RhoA. Functional assignment of the Hr1 repeat motif

21 January 2018

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The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

21 January 2018

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Mutational analysis of novel effector domains in Rac1 involved in the activation of nicotinamide adenine dinucleotide phosphate (reduced) oxidase

21 January 2018

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The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

21 January 2018

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Crystal structure of RhoA-GDP and its functional implications

21 January 2018

1 reference

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Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2

21 January 2018

1 reference

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Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

21 January 2018

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Biological and biochemical properties of human rasH genes mutated at codon 61.

21 January 2018

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Determination of interaction sites on the small G protein RhoA for phospholipase D

21 January 2018

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RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

21 January 2018

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A Rac1 effector site controlling mitogenesis through superoxide production

21 January 2018

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Different regions of Rho determine Rho-selective binding of different classes of Rho target molecules.

21 January 2018

1 reference

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Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue

21 January 2018

1 reference

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Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

21 January 2018

1 reference

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Structural determinants required for the interaction between Rho GTPase and the GTPase-activating domain of p190

21 January 2018

1 reference

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Definition of the switch surface in the solution structure of Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.4551

Transformation activity of Cdc42 requires a region unique to Rho-related proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.4551

Cloning of bovine GAP and its interaction with oncogenic ras p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.4551

Rac "insert region" is a novel effector region that is implicated in the activation of NADPH oxidase, but not PAK65

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.4551

Characterization of the interaction between RhoA and the amino-terminal region of PKN

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.4551

Rac binding to p67(phox). Structural basis for interactions of the Rac1 effector region and insert region with components of the respiratory burst oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.4551

release_3ot7cujzwjdbhbyw3mhsfbdpjq

21 January 2018

Identifiers

DOI

10.1074/JBC.274.8.4551

0 references

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3ot7cujzwjdbhbyw3mhsfbdpjq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference