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Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication.
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication
(English)
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
main subject
virus
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author
Peter Palese
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
Michael Bergmann
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
Adolfo García-Sastre
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
E Carnero
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
H Pehamberger
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
K Wolff
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
T Muster
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 July 2000
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
74
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
6203-6206
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
13
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
cites work
PKR; a sentinel kinase for cellular stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
retrieved
17 March 2017
Interaction of influenza virus NS1 protein and the human homologue of Staufen in vivo and in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
retrieved
17 March 2017
Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
retrieved
17 March 2017
The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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17 March 2017
The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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17 March 2017
Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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17 March 2017
Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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17 March 2017
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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17 March 2017
Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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7 April 2017
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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7 April 2017
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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7 April 2017
Reovirus therapy of tumors with activated Ras pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
Transfectant influenza A viruses with long deletions in the NS1 protein grow efficiently in Vero cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
The N-terminal half of the influenza virus NS1 protein is sufficient for nuclear retention of mRNA and enhancement of viral mRNA translation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
retrieved
29 September 2017
The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A)
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
Tumor-suppressor genes: news about the interferon connection
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
Influenza virus regulates protein synthesis during infection by repressing autophosphorylation and activity of the cellular 68,000-Mr protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
The double stranded RNA-activated protein kinase induced by interferon: dsRNA-PK.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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29 September 2017
Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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3 June 2018
Biochemical and genetic evidence for complex formation between the influenza A virus NS1 protein and the interferon-induced PKR protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
retrieved
3 June 2018
The double-stranded RNA-dependent protein kinase PKR: structure and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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3 June 2018
Activation of IFN-alpha, IFN-gamma, MxA, and IFN regulatory factor 1 genes in influenza A virus-infected human peripheral blood mononuclear cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
retrieved
3 June 2018
Oncogenic ras induces an inhibitor of double-stranded RNA-dependent eukaryotic initiation factor 2 alpha-kinase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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3 June 2018
Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
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27 November 2018
Regulation of IFN-alpha/beta, MxA, 2',5'-oligoadenylate synthetase, and HLA gene expression in influenza A-infected human lung epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
retrieved
27 November 2018
Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
retrieved
27 November 2018
The influenza virus NS1 protein: a novel inhibitor of pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
retrieved
27 November 2018
The influenza virus NS1 protein binds to a specific region in human U6 snRNA and inhibits U6-U2 and U6-U4 snRNA interactions during splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112122
retrieved
27 November 2018
Cleavage of oligoribonucleotides by the 2',5'-oligoadenylate- dependent ribonuclease L
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10846107
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Activated N-ras contributes to the chemoresistance of human melanoma in severe combined immunodeficiency (SCID) mice by blocking apoptosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10846107
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interferon Action: RNA Cleavage Pattern of a (2′-5′)Oligoadenylate—Dependent Endonuclease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10846107
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
2-Aminopurine inhibits the double-stranded RNA-dependent protein kinase both in vitro and in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10846107
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/JVI.74.13.6203-6206.2000
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PMCID
112122
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed ID
10846107
1 reference
stated in
Europe PubMed Central
PMCID
112122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10846107%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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