(Q28611402)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

review article

1 reference

title

Role of CHK2 in cancer development (English)

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

author

Cristobal Belda Iniesta

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

author name string

Rosario Perona

1

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Verónica Moncho-Amor

2

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Rosario Machado-Pinilla

3

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Isabel Sánchez Pérez

5

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

publication date

1 September 2008

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

Clinical and Translational Oncology

14 January 2020

published in

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

10

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

page(s)

538-542

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

issue

9

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s12094-008-0248-5

14 January 2020

exact match

0 references

cites work

Dual induction of apoptosis and senescence in cancer cells by Chk2 activation: checkpoint activation as a strategy against cancer

1 reference

12 December 2020

Inhibitors of checkpoint kinases: from discovery to the clinic.

1 reference

12 December 2020

Cdc25: mechanisms of checkpoint inhibition and recovery

1 reference

12 December 2020

Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage

1 reference

12 December 2020

Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells

1 reference

12 December 2020

G2 checkpoint abrogators as anticancer drugs

1 reference

12 December 2020

CHK2 kinase: cancer susceptibility and cancer therapy - two sides of the same coin?

1 reference

12 December 2020

Alterations of Chk1 and Chk2 expression in colon cancer.

1 reference

12 December 2020

CHEK2 mutations in primary glioblastomas.

1 reference

12 December 2020

Detecting, signalling and repairing DNA double-strand breaks.

1 reference

12 December 2020

The role of double-strand break repair — insights from human genetics

1 reference

12 December 2020

Mutation analysis of the CHK2 gene in breast carcinoma and other cancers

1 reference

12 December 2020

The CHEK2*1100delC variant acts as a breast cancer risk modifier in non-BRCA1/BRCA2 multiple-case families

1 reference

12 December 2020

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

12 December 2020

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair

1 reference

12 December 2020

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

1 reference

12 December 2020

DNA repair inhibitors in cancer treatment.

1 reference

12 December 2020

CHEK2 variants predispose to benign, borderline and low-grade invasive ovarian tumors

1 reference

12 December 2020

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

1 reference

12 December 2020

CHEK2 is a multiorgan cancer susceptibility gene

1 reference

12 December 2020

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

1 reference

12 December 2020

Genetic and epigenetic analysis of CHEK2 in sporadic breast, colon, and ovarian cancers

1 reference

12 December 2020

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

1 reference

12 December 2020

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

1 reference

12 December 2020

Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2

1 reference

12 December 2020

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

12 December 2020

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

1 reference

12 December 2020

Cellular responses to DNA damage: one signal, multiple choices

1 reference

12 December 2020

Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes

1 reference

12 December 2020

Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining.

1 reference

12 December 2020

The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1

1 reference

12 December 2020

Activated checkpoint kinase 2 provides a survival signal for tumor cells

1 reference

12 December 2020

Germ-line alterations in MSR1 gene and prostate cancer risk

1 reference

12 December 2020

Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazoles

1 reference

12 December 2020

Targeted cancer therapies based on the inhibition of DNA strand break repair

1 reference

12 December 2020

Excess risk for contralateral breast cancer in CHEK2*1100delC germline mutation carriers.

1 reference

12 December 2020

CHEK2 I157T associates with familial and sporadic colorectal cancer

1 reference

12 December 2020

A cancer family syndrome in twenty-four kindreds

1 reference

12 December 2020

Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining

1 reference

12 December 2020

10.1007/S12094-008-0248-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796370%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

2 references

3 February 2017