(Q28611432)

12 December 2020

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

12 December 2020

1 reference

12 December 2020

Wild-type p53 can inhibit oncogene-mediated focus formation

1 reference

12 December 2020

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

12 December 2020

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2

1 reference

12 December 2020

Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication

1 reference

12 December 2020

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

12 December 2020

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

1 reference

12 December 2020

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

12 December 2020

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

12 December 2020

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

1 reference

12 December 2020

An evolutionary perspective on apoptosis.

1 reference

12 December 2020

Redundant cyclin overexpression and gene amplification in breast cancer cells

1 reference

12 December 2020

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

1 reference

12 December 2020

Anaplastic Wilms' tumour, a subtype displaying poor prognosis, harbours p53 gene mutations

1 reference

12 December 2020

Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product

1 reference

12 December 2020

The MCK enhancer contains a p53 responsive element

1 reference

12 December 2020

Proliferating cell nuclear antigen is required for DNA excision repair

1 reference

12 December 2020

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1 reference

12 December 2020

A cancer family syndrome in twenty-four kindreds

1 reference

12 December 2020

Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus

1 reference

12 December 2020

The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae

1 reference

12 December 2020

How loops, beta sheets, and alpha helices help us to understand p53.

1 reference

12 December 2020

p53 transgenic mice: accelerated erythroleukemia induction by Friend virus

1 reference

12 December 2020

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

1 reference

12 December 2020

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

1 reference

12 December 2020

Participation of p53 protein in the cellular response to DNA damage

1 reference

12 December 2020

Checkpoints: controls that ensure the order of cell cycle events

1 reference

12 December 2020

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

12 December 2020

Structural aspects of the p53 protein in relation to gene evolution

1 reference

12 December 2020

Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning

1 reference

12 December 2020

Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man. Progress in the elucidation of the underlying biochemical defect

1 reference

12 December 2020

p53: at the crossroads of molecular carcinogenesis and risk assessment

1 reference

12 December 2020

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

1 reference

12 December 2020

T antigen is bound to a host protein in SY40-transformed cells

1 reference

12 December 2020

p53: a glimpse at the puppet behind the shadow play

1 reference

12 December 2020

SV40 T antigen binds specifically to a cellular 53 K protein in vitro

1 reference

12 December 2020

Apoptosis in cancer therapy: crossing the threshold

1 reference

12 December 2020

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

12 December 2020

p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis

1 reference

12 December 2020

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

12 December 2020

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

1 reference

12 December 2020

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

12 December 2020

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

12 December 2020

In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice

1 reference

12 December 2020

Wild-type p53 binds to the TATA-binding protein and represses transcription

1 reference

12 December 2020

Gene rearrangement and overexpression of PRAD1 in lymphoid malignancy with t(11;14)(q13;q32) translocation

1 reference

12 December 2020

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

1 reference

12 December 2020

The tumor suppressor genes

1 reference

12 December 2020

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation.

1 reference

12 December 2020

Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

1 reference

12 December 2020

A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice

1 reference

12 December 2020

p53 mutations increase resistance to ionizing radiation

1 reference

12 December 2020

Apoptosis and programmed cell death in immunity

1 reference

12 December 2020

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

1 reference

12 December 2020

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

12 December 2020

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

1 reference

12 December 2020

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1 reference

12 December 2020

Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C

1 reference

12 December 2020

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

12 December 2020

Regulation of the human hsp70 promoter by p53

1 reference

12 December 2020

NF-kappa B activation by ultraviolet light not dependent on a nuclear signal.

1 reference

12 December 2020

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

1 reference

12 December 2020

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

12 December 2020

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

1 reference

12 December 2020

Suppression of human colorectal carcinoma cell growth by wild-type p53

1 reference

12 December 2020

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

1 reference

12 December 2020

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

1 reference

12 December 2020

Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice.

1 reference

12 December 2020

The p53 proto-oncogene can act as a suppressor of transformation

1 reference

12 December 2020

Inhibition of p34cdc2 kinase activity by etoposide or irradiation as a mechanism of G2 arrest in Chinese hamster ovary cells

1 reference

12 December 2020

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

1 reference

12 December 2020

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents

1 reference

12 December 2020

p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer

1 reference

12 December 2020

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

12 December 2020

Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death

1 reference

12 December 2020

Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood

1 reference

12 December 2020

Gain of function mutations in p53.

1 reference

12 December 2020

Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

1 reference

12 December 2020

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

1 reference

12 December 2020

WAF1, a potential mediator of p53 tumor suppression

1 reference

12 December 2020

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

1 reference

12 December 2020

p53 domains: identification and characterization of two autonomous DNA-binding regions.

1 reference

12 December 2020

The role of p34 kinases in the G1 to S-phase transition

1 reference

12 December 2020

A novel cyclin encoded by a bcl1-linked candidate oncogene

1 reference

12 December 2020

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

1 reference

12 December 2020

Tight DNA binding and oligomerization are dispensable for the ability of p53 to transactivate target genes and suppress transformation.

1 reference

12 December 2020

Animal cell cycles and their control

1 reference

12 December 2020

Characterization of a candidate bcl-1 gene

1 reference

12 December 2020

The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro

1 reference

12 December 2020

Amplification of cyclin genes in colorectal carcinomas

1 reference

12 December 2020

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

1 reference

12 December 2020

Radiosensitivity in ataxia-telangiectasia: a new explanation

1 reference

12 December 2020

p53 mutations in human cancers

1 reference

12 December 2020

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

12 December 2020

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

1 reference

12 December 2020

Characterization of the in vitro interaction between SV40 T antigen and p53: mapping the p53 binding site

1 reference

12 December 2020

Ionizing radiation induces rapid tyrosine phosphorylation of p34cdc2

1 reference

12 December 2020

Premature p34cdc2 activation required for apoptosis.

1 reference

12 December 2020

Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein

1 reference

12 December 2020

Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin

1 reference

12 December 2020

Genetic mechanisms of tumor suppression by the human p53 gene

1 reference

12 December 2020

Identification of p53 as a sequence-specific DNA-binding protein

1 reference

12 December 2020

Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes.

1 reference

12 December 2020

Ataxia-telangiectasia: an interdisciplinary approach to pathogenesis

1 reference

12 December 2020

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

12 December 2020

Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line

1 reference

12 December 2020

A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization

1 reference

12 December 2020

p21 is a universal inhibitor of cyclin kinases

1 reference

12 December 2020

DNA damage, oncogenesis and the p53 tumour-suppressor gene

1 reference

12 December 2020