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The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells
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scholarly article
1 reference
stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
title
The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells
(English)
1 reference
stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
author name string
U. Herbig
series ordinal
1
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stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
C. A. Marlar
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
E. Fanning
series ordinal
3
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stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
publication date
1 August 1999
1 reference
stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
published in
Molecular Biology of the Cell
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stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
volume
10
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stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
page(s)
2631–2645
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stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
issue
8
1 reference
stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
cites work
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The DNA replication fork in eukaryotic cells.
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PubMed Central
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Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase
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PubMed Central
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Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells
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Initiation of DNA replication in eukaryotic cells
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Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2
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PubMed Central
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The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast
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PubMed Central
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Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs
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PubMed Central
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17 March 2017
Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast
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17 March 2017
Coordinate binding of ATP and origin DNA regulates the ATPase activity of the origin recognition complex
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A human protein related to yeast Cdc6p
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17 March 2017
The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts
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An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast
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17 March 2017
A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication
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17 March 2017
The Saccharomyces cerevisiae CDC6 gene is transcribed at late mitosis and encodes a ATP/GTPase controlling S phase initiation
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17 March 2017
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
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17 March 2017
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Structure of the recA protein–ADP complex
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17 March 2017
Two steps in the assembly of complexes at yeast replication origins in vivo
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7 April 2017
The role of nucleotide binding and hydrolysis in the function of the fission yeast cdc18(+) gene product
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3 June 2018
The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin
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3 June 2018
sud1(+) targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast
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Functional interactions among the subunits of replication factor C potentiate and modulate its ATPase activity
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3 June 2018
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3 June 2018
Putting it all together: building a prereplicative complex
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3 June 2018
Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation
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3 June 2018
Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.
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3 June 2018
Interaction of the S phase regulator cdc18 with cyclin-dependent kinase in fission yeast.
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3 June 2018
ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae
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3 June 2018
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases
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3 June 2018
cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.
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3 June 2018
Interaction of Cdc2 and Cdc18 with a fission yeast ORC2-like protein
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3 June 2018
Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.
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3 June 2018
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Accurate determination of DNA content in single cell nuclei stained with Hoechst 33258 fluorochrome at high salt concentration
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3 June 2018
Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders.
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Cdc6p establishes and maintains a state of replication competence during G1 phase.
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27 November 2018
The fission yeast cdc18+ gene product couples S phase to START and mitosis.
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27 November 2018
ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10436018
retrieved
12 December 2020
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A simple method of reducing the fading of immunofluorescence during microscopy
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10436018
retrieved
12 December 2020
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Identifiers
DOI
10.1091/MBC.10.8.2631
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PMCID
25495
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PubMed ID
10436018
1 reference
stated in
PubMed
PubMed ID
10436018
retrieved
3 February 2017
ResearchGate publication ID
12863797
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