(Q47693928)

4 February 2018

title

Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders. (English)

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4 February 2018

John Francis Xavier Diffley

author

series ordinal

2

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4 February 2018

author name string

G Perkins

series ordinal

1

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4 February 2018

publication date

1 July 1998

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4 February 2018

published in

Molecular Cell

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4 February 2018

volume

2

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4 February 2018

page(s)

23-32

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4 February 2018

issue

1

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4 February 2018

A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast

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The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts

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Characterization of the five replication factor C genes of Saccharomyces cerevisiae

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S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state.

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Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

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The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast

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Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

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Functional inactivation of genes by dominant negative mutations

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cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.

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Putting it all together: building a prereplicative complex

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7 January 2021

p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast

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7 January 2021

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.

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Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast

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7 January 2021

Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs

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7 January 2021

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7 January 2021

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Identifiers

DOI

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4 February 2018

PubMed ID

9702188

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4 February 2018