(Q28647896)

English

A possible role of acrolein in diabetic retinopathy: involvement of a VEGF/TGFβ signaling pathway of the retinal pigment epithelium in hyperglycemia

scientific article

In more languages

Statements

scholarly article

0 references

A possible role of acrolein in diabetic retinopathy: involvement of a VEGF/TGFβ signaling pathway of the retinal pigment epithelium in hyperglycemia (English)

0 references

sensory nervous system

0 references

1 reference

based on heuristic

inferred from title

diabetic retinopathy

1 reference

based on heuristic

inferred from title

author name string

Jeffery Grigsby

1

0 references

Brandi Betts

2

0 references

Eileen Vidro-Kotchan

3

0 references

Richard Culbert

4

0 references

Andrew Tsin

5

0 references

language of work or name

0 references

publication date

November 2012

0 references

Current Eye Research

0 references

37

0 references

11

0 references

1045-53

0 references

ALK7 expression is specific for adipose tissue, reduced in obesity and correlates to factors implicated in metabolic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

17 March 2017

Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

17 March 2017

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

17 March 2017

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

17 March 2017

Biochemistry and molecular cell biology of diabetic complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

17 March 2017

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

17 March 2017

Pigment epithelium-derived factor: a potent inhibitor of angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

17 March 2017

Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

17 March 2017

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

17 March 2017

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

7 April 2017

Ginsenoside-Rb1 Induces ARPE-19 Proliferation and Reduces VEGF Release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Effects of tamoxifen versus raloxifene on retinal capillary endothelial cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

NBHA reduces acrolein-induced changes in ARPE-19 cells: possible involvement of TGFβ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Evidence supporting a role for N-(3-formyl-3,4-dehydropiperidino)lysine accumulation in Müller glia dysfunction and death in diabetic retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Hydroxytyrosol protects retinal pigment epithelial cells from acrolein-induced oxidative stress and mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier--implications for the pathogenesis of diabetic retinopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

α-Tocopherol is an effective Phase II enzyme inducer: protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Role of Smad3, acting independently of transforming growth factor-beta, in the early induction of Wnt-beta-catenin signaling by parathyroid hormone in mouse osteoblastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Acrolein, a ubiquitous pollutant and lipid hydroperoxide product, inhibits antiviral activity of interferon-alpha: relevance to hepatitis C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Acrolein-derived DNA adduct formation in human colon cancer cells: its role in apoptosis induction by docosahexaenoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Acrolein toxicity: Comparison with reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Molecular mechanisms of the conjugated alpha,beta-unsaturated carbonyl derivatives: relevance to neurotoxicity and neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Quantitation of acrolein-derived (3-hydroxypropyl)mercapturic acid in human urine by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry: effects of cigarette smoking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Oxidative damage in mild cognitive impairment and early Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Estimating risk from ambient concentrations of acrolein across the United States.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

The concept of "aldehyde load" in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Survival signaling in retinal pigment epithelial cells in response to oxidative stress: significance in retinal degenerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

ARPE-19 cell growth and cell functions in euglycemic culture media

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Antioxidants reduce cone cell death in a model of retinitis pigmentosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Neurotoxicity of reactive aldehydes: the concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Bone morphogenetic protein-4 enhances vascular endothelial growth factor secretion by human retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Polyamine oxidase and acrolein as novel biochemical markers for diagnosis of cerebral stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Toxicity and detoxification of lipid-derived aldehydes in cultured retinal pigmented epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Regulation mechanisms of retinal pigment epithelial cell migration by the TGF-beta superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Increase in putrescine, amine oxidase, and acrolein in plasma of renal failure patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Current status of acrolein as a lipid peroxidation product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Carbonyl stress in the pathogenesis of diabetic nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Metabolism and distribution of [2,3-14C]acrolein in Sprague-Dawley rats. II. Identification of urinary and fecal metabolites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Lilly Lecture 1993. Glycation and diabetic complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Formation of cyclic 1,N2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

3 June 2018

Glucose-stimulated acrolein production from unsaturated fatty acids.

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins.

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Evaluation of N (epsilon)-(3-formyl-3,4-dehydropiperidino)lysine as a novel biomarker for the severity of diabetic retinopathy

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Vitreous polyamines spermidine, putrescine, and spermine in human proliferative disorders of the retina

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Müller glial dysfunction during diabetic retinopathy in rats is linked to accumulation of advanced glycation end-products and advanced lipoxidation end-products.

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Formation of advanced glycosylation end products and oxidative stress in young patients with type 1 diabetes

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Increased Urinary Levels of Pentosidine, Pyrraline and Acrolein Adduct in Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Serum protein acrolein adducts: utility in detecting oxidant stress in hemodialysis patients and reversal using a vitamin E-bonded hemodialyzer

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Oocytes determine cumulus cell lineage in mouse ovarian follicles.

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

A model of hemorrhagic cystitis induced with acrolein in mice.

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Acrolein induces inflammatory response underlying endothelial dysfunction: a risk factor for atherosclerosis

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Intense correlation between brain infarction and protein-conjugated acrolein.

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Resveratrol protects human retinal pigment epithelial cells from acrolein-induced damage

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5).

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Role of TGF-beta in the retinoic acid-induced inhibition of proliferation and melanin synthesis in chick retinal pigment epithelial cells in vitro

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Influence of glutathione S-transferase polymorphisms on genotoxic effects induced by tobacco smoke.

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Lipid peroxidation products inhibit dopamine catabolism yielding aberrant levels of a reactive intermediate

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Diabetes impairs the enzymatic disposal of 4-hydroxynonenal in rat liver.

1 reference

https://api.crossref.org/works/10.3109%2F02713683.2012.713152

21 January 2018

Oxidative damage in age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482234

27 November 2018

Transforming growth factor beta 2 is the predominant isoform in the neural retina, retinal pigment epithelium-choroid and vitreous of the monkey eye

1 reference

https://pubmed.ncbi.nlm.nih.gov/22906079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesized TGF-beta s in RPE regulates cellular proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22906079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in proliferative vitreoretinal disorders: possible involvement of TGF-beta-induced RPE cell apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22906079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22906079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased NADH oxidase activity in the retina of the BBZ/Wor diabetic rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22906079

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3109/02713683.2012.713152

0 references

0 references

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28647896&oldid=1629082565"