(Q36370381)

13 August 2017

1 reference

title

Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health (English)

1 reference

13 August 2017

0 references

Peter J O'Brien

1

1 reference

13 August 2017

Arno G Siraki

series ordinal

2

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13 August 2017

Nandita Shangari

series ordinal

3

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13 August 2017

language of work or name

English

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publication date

1 August 2005

1 reference

Critical Reviews in Toxicology

13 August 2017

published in

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13 August 2017

volume

35

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13 August 2017

issue

7

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13 August 2017

page(s)

609-662

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Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity

13 August 2017

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Heterogeneity of anthracycline antibiotic carbonyl reductases in mammalian livers

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Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells

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Increased circulating products of lipid peroxidation in patients with alcoholic liver disease.

21 January 2018

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Metabolism of retinaldehyde and other aldehydes in soluble extracts of human liver and kidney

21 January 2018

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Morphofunctional mitochondrial response to methylglyoxal toxicity in Bufo bufo embryos.

21 January 2018

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Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsatu

21 January 2018

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Chemical modification of rat liver microsomal glutathione transferase defines residues of importance for catalytic function

21 January 2018

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4-Hydroxynonenal affects pRb/E2F pathway in HL-60 human leukemic cells

21 January 2018

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Glycoxidation and lipoxidation in atherogenesis

21 January 2018

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Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases

21 January 2018

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Identification of oxidized derivatives of neuroketals

21 January 2018

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Inactivation of carbonyl reductase from human brain by phenylglyoxal and 2,3-butanedione: a comparison with aldehyde reductase and aldose reductase

21 January 2018

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Kinetics of carbonyl reductase from human brain

21 January 2018

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Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice.

21 January 2018

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Evidence for the presence of anion-recognition sites in pig-liver aldehyde reductase. Modification by phenyl glyoxal and p-carboxyphenyl glyoxal of an arginyl residue located close to the substrate-binding site.

21 January 2018

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Effect of allyl alcohol on xanthine dehydrogenase activity in the perfused rat liver

21 January 2018

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Biochemistry and molecular cell biology of diabetic complications

21 January 2018

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The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis

21 January 2018

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Dependence of aldehyde dehydrogenase-mediated oxazaphosphorine resistance on soluble thiols: importance of thiol interactions with the secondary metabolite acrolein

21 January 2018

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Characterization of nucleoside adducts of cis-2-butene-1,4-dial, a reactive metabolite of furan

21 January 2018

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Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440591002183

The effect of a novel irreversible inhibitor of aldehyde dehydrogenases 1 and 3 on tumour cell growth and death

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440591002183

Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Observation of volatile and semi-volatile carbonyls in an Algerian urban environment using dinitrophenylhydrazine/silica-HPLC and pentafluorophenylhydrazine/silica-GC-MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Role of 4-hydroxynonenal in modification of cytochrome c oxidase in ischemia/reperfused rat heart

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440591002183

Identification of the enzymatic mechanism of nitroglycerin bioactivation

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440591002183

Down-modulation of nuclear localisation and pro-fibrogenic effect of 4-hydroxy-2,3-nonenal by thiol- and carbonyl-reagents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Correlation between chemical composition and antibacterial activity of essential oils of some aromatic medicinal plants growing in the Democratic Republic of Congo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Selective protein covalent binding and target organ toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

A review and meta-analysis of formaldehyde exposure and leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Amine metabolism: a novel path to coronary artery vasospasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Simulation modeling of the tissue disposition of formaldehyde to predict nasal DNA-protein cross-links in Fischer 344 rats, rhesus monkeys, and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Cyclophosphamide cystitis—Identification of acrolein as the causative agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The gene encoding hydroxypyruvate reductase (GRHPR) is mutated in patients with primary hyperoxaluria type II

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Formaldehyde production promoted by rat nasal cytochrome P-450-dependent monooxygenases with nasal decongestants, essences, solvents, air pollutants, nicotine, and cocaine as substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Hepatocellular damage with ethacrynic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

D-Lactate transport and metabolism in rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Adverse reactions to fragrances

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Gas chromatographic analysis of reactive carbonyl compounds formed from lipids upon UV-irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Ambient air measurement of acrolein and other carbonyls at the Oakland-San Francisco Bay Bridge toll plaza

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Mechanisms of idiosyncratic drug reactions: the case of felbamate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Inhibition by cyanamide of 4-hydroxycyclophosphamide/aldophosphamide oxidation to carboxyphosphamide

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440591002183

Human carbonyl reductase catalyzes reduction of 4-oxonon-2-enal

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Characterization of the rat aflatoxin B1 aldehyde reductase gene, AKR7A1. Structure and chromosomal localization of AKR7A1 as well as identification of antioxidant response elements in the gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: structure-based mechanism of conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Teratogenicity of 3-deoxyglucosone and diabetic embryopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

High-performance liquid chromatographic-fluorometric determination of glyoxal, methylglyoxal, and diacetyl in urine by prederivatization to pteridinic rings

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Identification of formaldehyde releasers and occurrence of formaldehyde and formaldehyde releasers in registered chemical products

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Cinnamaldehyde content in foods determined by gas chromatography-mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Reactions of hypochlorous acid with tyrosine and peptidyl-tyrosyl residues give dichlorinated and aldehydic products in addition to 3-chlorotyrosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Characteristics of major mutagenicity of instant coffee.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Thiolation of protein-bound carcinogenic aldehyde. An electrophilic acrolein-lysine adduct that covalently binds to thiols

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Detoxication of the environmental pollutant acrolein by a rat liver aldo-keto reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Population distribution of aldehyde dehydrogenase-2 genetic polymorphism: implications for risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Human neutrophils employ myeloperoxidase to convert alpha-amino acids to a battery of reactive aldehydes: a pathway for aldehyde generation at sites of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Formaldehyde toxicity--new understanding

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Polymorphism in the 5'-End of the Aldose Reductase Gene Is Strongly Associated With the Development of Diabetic Nephropathy in Type I Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Epidemic of liver disease caused by hydrochlorofluorocarbons used as ozone-sparing substitutes of chlorofluorocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Alpha-thujone (the active component of absinthe): gamma-aminobutyric acid type A receptor modulation and metabolic detoxification

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Rapid induction of apoptosis by deregulated uptake of polyamine analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Disposition, metabolism, and toxicity of methyl tertiary butyl ether, an oxygenate for reformulated gasoline

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Proteasomal dysfunction induced by 4-hydroxy-2,3-trans-nonenal, an end-product of lipid peroxidation: a mechanism contributing to neurodegeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Endogenous formation of protein adducts with carcinogenic aldehydes: implications for oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Inhibition of the mitochondrial permeability transition by aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Molecular basis of enzyme inactivation by an endogenous electrophile 4-hydroxy-2-nonenal: identification of modification sites in glyceraldehyde-3-phosphate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Hemorrhagic cystitis as an unexpected adverse reaction to temozolomide: case report

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Neuroprotection in cerebral ischemia by neutralization of 3-aminopropanal

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Identification of a reactive metabolite of terbinafine: insights into terbinafine-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

5-Hydroxymethylfurfural: assessment of mutagenicity, DNA-damaging potential and reactivity towards cellular glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The aldo-keto reductase (AKR) superfamily: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Methylglyoxal toxicity in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Aldehyde reductase is a major protein associated with 3-deoxyglucosone reductase activity in rat, pig and human livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Reactivity of atropaldehyde, a felbamate metabolite in human liver tissue in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Evaluation of case reports of aplastic anemia among patients treated with felbamate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The toxicity of inhaled methanol vapors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Human liver fatty aldehyde dehydrogenase: microsomal localization, purification, and biochemical characterization

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440591002183

Human liver alcohol dehydrogenases catalyze the oxidation of the intermediary alcohols of the shunt pathway of mevalonate metabolism

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408440591002183

The involvement of cytochrome P4502E1 in 2-bromoethanol-induced hepatocyte cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Idiosyncratic drug reactions: the reactive metabolite syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Evidence for the identity of glutathione-dependent formaldehyde dehydrogenase and class III alcohol dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The high resolution crystal structure of rat liver AKR7A1: understanding the substrate specificites of the AKR7 family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Role of p38 mitogen-activated protein kinase in the 4-hydroxy-2-nonenal-induced cyclooxygenase-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Reaction kinetics of DNA-histone crosslinking by vinyl acetate and acetaldehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Mutagenic activity of halogenated propanes and propenes: effect of bromine and chlorine positioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Overexpression of aldose reductase in liver cancers may contribute to drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Inhaled formaldehyde: exposure estimation, hazard characterization, and exposure-response analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Inhibition of proliferation of human leukaemia 60 cells by diethyl esters of glyoxalase inhibitors in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

4-hydroxynonenal decreases interleukin-6 expression and protein production in primary rat Kupffer cells by inhibiting nuclear factor-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Sensitivity of aldehyde dehydrogenases in murine tumor and hematopoietic progenitor cells to inhibition by chloral hydrate as determined by the ability of chloral hydrate to potentiate the cytotoxic action of mafosfamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Analysis of Formaldehyde in Tobacco Smoke by High Performance Liquid Chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

4-Biphenylaldehyde and 9-anthraldehyde: two fluorescent substrates for determining P450 enzyme activities in rat and human

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Lipid peroxidation-DNA damage by malondialdehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Oxy radicals, lipid peroxidation and DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Naturally occurring carbonyl compounds are mutagens in Salmonella tester strain TA104.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Endogenous DNA damage and mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Xenobiotic carbonyl reduction and physiological steroid oxidoreduction. The pluripotency of several hydroxysteroid dehydrogenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Purification, characterization and NNK carbonyl reductase activities of 11beta-hydroxysteroid dehydrogenase type 1 from human liver: enzyme cooperativity and significance in the detoxification of a tobacco-derived carcinogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Occupational exposures in California wildland fire fighting

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Effect of aspirin on incidence and growth of aberrant crypt foci induced in the rat colon by 1,2-dimethylhydrazine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Genotoxicity of methylglyoxal: cytogenetic damage in human lymphocytes in vitro and in intestinal cells of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Advanced glycation and lipoxidation end products: reactive carbonyl compounds-related uraemic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Cytochrome P450 2E1 metabolically activates propargyl alcohol: propiolaldehyde-induced hepatocyte cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Dosimetry, toxicity and carcinogenicity of inspired acetaldehyde in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Acrylamide is formed in the Maillard reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Fogwater chemistry in a wood-burning community, western Oregon

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Methylglyoxal, an endogenous aldehyde, crosslinks DNA polymerase and the substrate DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Glyoxal, a major product of DNA oxidation, induces mutations at G:C sites on a shuttle vector plasmid replicated in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Acute toxicity of fluorinated ether anesthetics: Role of 2,2,2-trifluoroethanol and other metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Identification of bovine heart cytochrome c oxidase subunits modified by the lipid peroxidation product 4-hydroxy-2-nonenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Mutagens in coffee and other beverages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Etheno DNA-base adducts from endogenous reactive species

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Halothane and hepatitis. Incidence, predisposing factors and exposure guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Effect of Kupffer cell inactivation on ethanol-induced protein adducts in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Modulating carbonyl cytotoxicity in intact rat hepatocytes by inhibiting carbonyl metabolizing enzymes. II. Aromatic aldehydes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Modulating carbonyl cytotoxicity in intact rat hepatocytes by inhibiting carbonyl-metabolizing enzymes. I. Aliphatic alkenals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Potent inhibition of human liver aldehyde oxidase by raloxifene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Imidazolium crosslinks derived from reaction of lysine with glyoxal and methylglyoxal are increased in serum proteins of uremic patients: evidence for increased oxidative stress in uremia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Paraformaldehyde sterilant use in vocational high school program.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

In vivo assessment of lipid peroxidation products associated with age-related neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The ubiquitous aldehyde reductase (AKR1A1) oxidizes proximate carcinogen trans-dihydrodiols to o-quinones: potential role in polycyclic aromatic hydrocarbon activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Reactive oxygen species affect mitochondrial electron transport complex I activity through oxidative cardiolipin damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Proteomic alterations of the variants of human aldehyde dehydrogenase isozymes correlate with hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Skin-sensitization structure-activity relationships for aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Electronic properties of the casein-methylglyoxal complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Carbonyl toxicology and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Betaine aldehyde dehydrogenase from rat liver mitochondrial matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Characterization of the glutathione binding site of aldose reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Fragrance chemicals in domestic and occupational products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by chlorpropamide analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Toxicology and carcinogenesis studies of microencapsulated citral in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

DNA damage by carbonyl stress in human skin cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

4-Hydroxy-2,3-alkenals as signal molecules modulating proliferative and adaptative cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The effects of different antineoplastic agents and of pretreatment by modulators on three melanoma lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Hepatic peroxisomal and microsomal enzyme induction by citral and linalool in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Alterations in renal mitochondrial respiration in response to the reactive oxoaldehyde methylglyoxal

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Two distinct pathways of formation of 4-hydroxynonenal. Mechanisms of nonenzymatic transformation of the 9- and 13-hydroperoxides of linoleic acid to 4-hydroxyalkenals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Coenzyme specificity of human monomeric carbonyl reductase: contribution of Lys-15, Ala-37 and Arg-38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Oxidation of polyamines and brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Distribution of volatile organic chemicals in outdoor and indoor air: a national VOCs data base

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Toxicity of glyoxals--role of oxidative stress, metabolic detoxification and thiamine deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The cytotoxic mechanism of glyoxal involves oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Cytotoxic action of methylglyoxal on insulin-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Selective vulnerability of spinal motor neurons to reactive dicarbonyl compounds, intermediate products of glycation, in vitro: implication of inefficient glutathione system in spinal motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Advanced glycation end-products: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Protein oxidation and degradation during proliferative senescence of human MRC-5 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Effect of methanol intoxication on free-radical induced protein oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The relative toxicity of compounds in mainstream cigarette smoke condensate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Human skin absorption and metabolism of the contact allergens, cinnamic aldehyde, and cinnamic alcohol

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Cloning of vascular adhesion protein 1 reveals a novel multifunctional adhesion molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The potency of inducers of NAD(P)H:(quinone-acceptor) oxidoreductase parallels their efficiency as substrates for glutathione transferases. Structural and electronic correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Aldehydic lipid peroxidation products derived from linoleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Structural and kinetic determinants of aldehyde reduction by aldose reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The novel aldehyde dehydrogenase gene, ALDH5, encodes an active aldehyde dehydrogenase enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

In vivo glycation of aldehyde reductase, a major 3-deoxyglucosone reducing enzyme: identification of glycation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Effects of glyoxal and methylglyoxal administration on gastric carcinogenesis in Wistar rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Isolation of glyoxalase II from two different compartments of rat liver mitochondria. Kinetic and immunochemical characterization of the enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Volatile isoprenoid constituents of fruits, vegetables and herbs cumulatively suppress the proliferation of murine B16 melanoma and human HL-60 leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The formaldehyde metabolic detoxification enzyme systems and molecular cytotoxic mechanism in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Monosaccharide autoxidation in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The glyoxalase system in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Embryo toxicity and teratogenicity of formaldehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Stable expression of rat dihydrodiol dehydrogenase (AKR1C9) in human breast MCF-7 cells results in the formation of PAH-o-quinones and enzyme mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Role of reactive aldehyde in cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Elevation of N-(carboxymethyl)valine residue in hemoglobin of diabetic patients. Its role in the development of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Mitochondrial aldehyde reductase: identification and characterization in rat liver and kidney cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Volatile chemicals identified in extracts from newly hybrid citrus, dekopon (Shiranuhi mandarin Suppl. J.).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Characterization of a major form of human isatin reductase and the reduced metabolite

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Interactions of alpha, beta-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Methylglyoxal metabolism and diabetic complications: roles of aldose reductase, glyoxalase-I, betaine aldehyde dehydrogenase and 2-oxoaldehyde dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Prevention of fructose-induced hypertension by dietary vitamins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Role of aldehyde dehydrogenases in endogenous and xenobiotic metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Circulating antibodies recognizing malondialdehyde-modified proteins in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Hepatic alcohol dehydrogenase activity in alcoholic subjects with and without liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Diabetes and advanced glycation endproducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

The metabolic activation of abacavir by human liver cytosol and expressed human alcohol dehydrogenase isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Trichloroethylene inhibits aldehyde dehydrogenase only for aliphatic aldehydes of short chains in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Effects of aldehyde dehydrogenase-2 genetic polymorphisms on metabolism of structurally different aldehydes in human liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

New biomarkers of Maillard reaction damage to proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Purification and characterization of human-brain aldose reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Carbonyl reductase provides the enzymatic basis of quinone detoxication in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

In vitro exposure to malondialdehyde-acetaldehyde adducted protein inhibits cell proliferation and viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Biological interactions of alpha,beta-unsaturated aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Identification of alpha-dicarbonyl scavengers for cellular protection against carbonyl stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Toxicity of ethacrynic acid in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Mitochondrial adenine nucleotide translocase is modified oxidatively during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Cytotoxic aldehydes as possible markers for childhood cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Emission of alcohols and carbonyl compounds from a spark ignition engine. Influence of fuel and air/fuel equivalence ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Involvement of caspases in 4-hydroxy-alkenal-induced apoptosis in human leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Cloning and sequencing of a copper-containing, topa quinone-containing monoamine oxidase from human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Initiation and promotion of colonic aberrant crypt foci in rats by 5-hydroxymethyl-2-furaldehyde in thermolyzed sucrose

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Hepatitis associated with terbinafine therapy: three case reports and a review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

A New Approach to the Study of Thiamine Deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

Characterization of Amino Acid and Glutathione Adducts ofcis-2-Butene-1,4-dial, a Reactive Metabolite of Furan

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440591002183

10.1080/10408440591002183

21 January 2018

Identifiers

DOI

1 reference

release_dvzridinpbethjoxu7a2pepo54

13 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dvzridinpbethjoxu7a2pepo54

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference