(Q28731029)

English

Improved preservation of residual beta cell function by atorvastatin in patients with recent onset type 1 diabetes and high CRP levels (DIATOR trial)

scientific article (publication date: 2012)

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scholarly article

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Improved preservation of residual beta cell function by atorvastatin in patients with recent onset type 1 diabetes and high CRP levels (DIATOR trial) (English)

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type-1 diabetes

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Christian Herder

4

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8

object named as

Lutz Heinemann

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9

object named as

Michael Roden

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author name string

Alexander Strom

1

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Hubert Kolb

2

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Stephan Martin

3

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Marie-Christine Simon

5

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Wolfgang Koenig

6

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Tim Heise

7

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Nanette C Schloot

10

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language of work or name

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publication date

2012

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7

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3

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e33108

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copyright license

Creative Commons Attribution 4.0 International

20 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

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Residual beta cell function in newly diagnosed type 1 diabetes after treatment with atorvastatin: the Randomized DIATOR Trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

17 March 2017

Acute-phase proteins and other systemic responses to inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

17 March 2017

Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Immunological and cardiometabolic risk factors in the prediction of type 2 diabetes and coronary events: MONICA/KORA Augsburg case-cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Atorvastatin exerts its anti-atherosclerotic effects by targeting the receptor for advanced glycation end products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Atorvastatin inhibits plaque development and adventitial neovascularization in ApoE deficient mice independent of plasma cholesterol levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Statin-induced Krüppel-like factor 2 expression in human and mouse T cells reduces inflammatory and pathogenic responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Accelerated increase in serum interleukin-1 receptor antagonist starts 6 years before diagnosis of type 2 diabetes: Whitehall II prospective cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

The pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodulation and thrombogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Mixed-meal tolerance test versus glucagon stimulation test for the assessment of beta-cell function in therapeutic trials in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Dual mode of HMG-CoA reductase inhibition on dendritic cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: new evidence for direct antiinflammatory effects of statins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Natural Course of Remission in IDDM During 1st yr After Diagnosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

3 June 2018

Effects of low-dosage simvastatin on rheumatoid arthritis through reduction of Th1/Th2 and CD4/CD8 ratios

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Simvastatin induces activation of the serine-threonine protein kinase AKT and increases survival of isolated human pancreatic islets

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Atorvastatin does not decrease or delay diabetes onset in two different mouse models of type 1 diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Atorvastatin inhibits T cell activation through 3-hydroxy-3-methylglutaryl coenzyme A reductase without decreasing cholesterol synthesis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Statins inhibit C-reactive protein-induced chemokine secretion, ICAM-1 upregulation and chemotaxis in adherent human monocytes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Simvastatin induces Foxp3+ T regulatory cells by modulation of transforming growth factor-beta signal transduction

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Statins attenuate high mobility group box-1 protein induced vascular endothelial activation : a key role for TLR4/NF-κB signaling pathway

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Impaired glucose tolerance is associated with increased serum concentrations of interleukin 6 and co-regulated acute-phase proteins but not TNF-alpha or its receptors

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Increased plasma interleukin-1 receptor antagonist levels in men with visceral obesity.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

CRP and IL-6 concentrations are associated with poor glycemic control despite preserved beta-cell function during the first year after diagnosis of type 1 diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Anti-inflammatory effect of lifestyle changes in the Finnish Diabetes Prevention Study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Chemokines as risk factors for type 2 diabetes: results from the MONICA/KORA Augsburg study, 1984-2002.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033108

21 January 2018

Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, function as inhibitors of cellular and molecular components involved in type I interferon production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

27 November 2018

Effects of pravastatin in prevention of diabetes and mechanism thereof: experiment with non-obese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308960

27 November 2018

Effect of statin and fibrate treatment on inflammation in type 2 diabetes. A randomized, cross-over study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22448235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of atorvastatin and its role on systemic cytokine network in treatment of acute experimental colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22448235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins as a newly recognized type of immunomodulator

1 reference

https://pubmed.ncbi.nlm.nih.gov/22448235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic factors for the course of beta cell function in autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22448235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atorvastatin Fails to Prevent the Development of Autoimmune Diabetes Despite Inhibition of Pathogenic -Cell-Specific CD8 T-Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22448235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simvastatin protects against multiple low-dose streptozotocin-induced type 1 diabetes in CD-1 mice and recurrence of disease in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22448235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0033108

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2012PLoSO...733108S

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