(Q28740645)

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Dependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G·T mispairs

scientific article (publication date: 5 May 2011)

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27 January 2020

Dependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G·T mispairs (English)

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27 January 2020

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Alexander C Drohat

2

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27 January 2020

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Atanu Maiti

1

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27 January 2020

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6 April 2011

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27 January 2020

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27 January 2020

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27 January 2020

5

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27 January 2020

545-553

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27 January 2020

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1 reference

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1 reference

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Human alkyladenine DNA glycosylase employs a processive search for DNA damage

1 reference

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1 reference

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1 reference

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Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition

1 reference

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1 reference

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The main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosine

1 reference

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Uracil-DNA glycosylase acts by substrate autocatalysis

1 reference

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Crystal structure of a thwarted mismatch glycosylase DNA repair complex

1 reference

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The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

1 reference

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17 March 2017

MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

1 reference

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Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability

1 reference

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17 March 2017

A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

1 reference

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17 March 2017

The purification of a mismatch-specific thymine-DNA glycosylase from HeLa cells

1 reference

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The CpG dinucleotide and human genetic disease

1 reference

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17 March 2017

The thymine-DNA glycosylase regulatory domain: residual structure and DNA binding

1 reference

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17 March 2017

Crystal structure of thymine DNA glycosylase conjugated to SUMO-1

1 reference

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Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase

1 reference

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7 April 2017

Stoichiometry and affinity for thymine DNA glycosylase binding to specific and nonspecific DNA

1 reference

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Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen

1 reference

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3 June 2018

Role of two strictly conserved residues in nucleotide flipping and N-glycosylic bond cleavage by human thymine DNA glycosylase

1 reference

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Mutational spectra of human cancer.

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3 June 2018

Coordinating the initial steps of base excision repair. Apurinic/apyrimidinic endonuclease 1 actively stimulates thymine DNA glycosylase by disrupting the product complex

1 reference

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Transition-state analysis of the DNA repair enzyme MutY.

1 reference

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Transient cyclical methylation of promoter DNA.

1 reference

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3 June 2018

Cyclical DNA methylation of a transcriptionally active promoter

1 reference

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3 June 2018

The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase

1 reference

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Excision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG.

1 reference

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Specificity of human thymine DNA glycosylase depends on N-glycosidic bond stability

1 reference

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Toward a detailed understanding of base excision repair enzymes: transition state and mechanistic analyses of N-glycoside hydrolysis and N-glycoside transfer

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Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation

1 reference

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Role of electrophilic and general base catalysis in the mechanism of Escherichia coli uracil DNA glycosylase.

1 reference

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Base analog and neighboring base effects on substrate specificity of recombinant human G:T mismatch-specific thymine DNA-glycosylase.

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Kinetic isotope effect studies of the reaction catalyzed by uracil DNA glycosylase: evidence for an oxocarbenium ion-uracil anion intermediate

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Uncatalyzed hydrolysis of deoxyuridine, thymidine, and 5-bromodeoxyuridine

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12 December 2020

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Studies of base pair kinetics by NMR measurement of proton exchange

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12 December 2020

based on heuristic

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Identifiers

10.1016/J.DNAREP.2011.03.004

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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27 January 2020

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21474392%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21474392%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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