(Q28743099)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Individual and cumulative effects of GWAS susceptibility loci in lung cancer: associations after sub-phenotyping for COPD (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

genome-wide association study

22 January 2020

main subject

0 references

chronic obstructive pulmonary disease

1 reference

1 reference

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

6

Gregory D Gamble

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1

Robert P Young

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Raewyn J Hopkins

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Chris F Whittington

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Bryan A Hay

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

3 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

e16476

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

22 January 2020

copyright license

start time

3 February 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

1 reference

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Genome-wide association study identifies five loci associated with lung function

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Lung cancer susceptibility model based on age, family history and genetic variants

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Lung cancer and chronic obstructive pulmonary disease: needs and opportunities for integrated research

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Genetic variation is associated with C-reactive protein levels in the Third National Health and Nutrition Examination Survey

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Inference of population structure using multilocus genotype data

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Rare variants create synthetic genome-wide associations

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

FAM13A locus in COPD is independently associated with lung cancer - evidence of a molecular genetic link between COPD and lung cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Pharmacological actions of statins: potential utility in COPD.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Variants in FAM13A are associated with chronic obstructive pulmonary disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Diagnosis of pulmonary malignancy after hospitalization for pneumonia.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

A rigorous and comprehensive validation: common genetic variations and lung cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Genome-based prediction of common diseases: methodological considerations for future research

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

A genome-wide association study of pulmonary function measures in the Framingham Heart Study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Dysregulated apoptosis and NFkappaB expression in COPD subjects

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

COPD prevalence is increased in lung cancer, independent of age, sex and smoking history

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Association of radiographic emphysema and airflow obstruction with lung cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Variants in nicotinic receptors and risk for nicotine dependence

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

How to interpret a genome-wide association study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Radical generation and alterations of erythrocyte integrity as bioindicators of diagnostic or prognostic value in COPD?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Forced expiratory volume in one second: not just a lung function test but a marker of premature death from all causes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Framingham Heart Study genome-wide association: results for pulmonary function measures

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Genome-wide association studies provide new insights into type 2 diabetes aetiology

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

The non-neuronal cholinergic system in the airways: an unappreciated regulatory role in pulmonary inflammation?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Nitrosamines as nicotinic receptor ligands

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Developing COPD: a 25 year follow up study of the general population

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Variants in the GH-IGF axis confer susceptibility to lung cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

ADAMs, cell migration and cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Epithelial-mesenchymal transition in lung cancer: is tobacco the "smoking gun"?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Familial lung cancer: genetic susceptibility and relationship to chronic obstructive pulmonary disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Down-regulation of the receptor for advanced glycation end-products (RAGE) supports non-small cell lung carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Genetic susceptibility to lung cancer: the role of DNA damage and repair.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Low lung function and incident lung cancer in the United States: data From the First National Health and Nutrition Examination Survey follow-up

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Inheritance and drug response

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Cancer risk and low-penetrance susceptibility genes in gene-environment interactions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

When can a risk factor be used as a worthwhile screening test?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Decline in FEV1 related to smoking status in individuals with severe alpha1-antitrypsin deficiency (PiZZ).

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Airways obstruction and the risk for lung cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Cumulative and reversible effects of lifetime smoking on simple tests of lung function in adults

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Genotypic and phenotypic similarities in pulmonary function among family members of adult monozygotic and dizygotic twins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Floating absolute risk: an alternative to relative risk in survival and case-control analysis avoiding an arbitrary reference group

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

Quantitative relationships between cigarette smoking and ventilatory function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033394

The natural history of chronic airflow obstruction revisited: an analysis of the Framingham offspring cohort

3 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Assessing the relationship between lung cancer risk and emphysema detected on low-dose CT of the chest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Lung cancer gene associated with COPD: triple whammy or possible confounding effect?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Improved estimates of floating absolute risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Linkage disequilibrium and the mapping of complex human traits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Expression of ADAMs ("a disintegrin and metalloprotease") in the human lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Baseline C-reactive protein is associated with incident cancer and survival in patients with cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Hospitalizations and mortality in the Lung Health Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Distinct clinical phenotypes of airways disease defined by cluster analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Evaluation of genetic tests for susceptibility to common complex diseases: why, when and how?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

Design of Case-controls Studies with Unscreened Controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016476

What are the odds that smoking will kill you?

21 January 2018

1 reference

12 December 2020

Complex segregation analysis reveals a multigene model for lung cancer

1 reference

12 December 2020

Cumulative association of five genetic variants with prostate cancer

1 reference

12 December 2020

Prevalence of chronic obstructive pulmonary disease among smokers aged 45 and up in Israel

1 reference

12 December 2020

High-sensitive C-reactive protein is associated with reduced lung function in young adults

1 reference

12 December 2020

Are COPD and lung cancer two manifestations of the same disease?

1 reference

12 December 2020

Chromosome 4q31 locus in COPD is also associated with lung cancer

1 reference

12 December 2020

Clinical features of 5,628 primary lung cancer patients: experience at Mayo Clinic from 1997 to 2003

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0016476

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

ADS bibcode

2011PLoSO...616476Y

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21304900%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

2 references