(Q28766365)

title

Insulin resistance and elevated triglyceride in muscle: more important for survival than "thrifty" genes? (English)

0 references

Insulin resistance and elevated triglyceride in muscle: more important for survival than ‘thrifty’ genes? (English)

1 reference

DOI

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.053926

30 March 2024

1 reference

1 reference

1 reference

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.053926

30 March 2024

2

N. A. Johnson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14608009

30 March 2024

author name string

S. R. Stannard

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14608009

30 March 2024

language of work or name

English

0 references

publication date

1 February 2004

0 references

7 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14608009

full work available at URL

30 March 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664785

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14608009

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1113%2Fjphysiol.2003.053926

30 March 2024

1 reference

DOI

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.053926

https://physoc.onlinelibrary.wiley.com/doi/pdf/10.1113/jphysiol.2003.053926

30 March 2024

1 reference

DOI

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.053926

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

30 March 2024

published in

Journal of Physiology

0 references

volume

554

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issue

Pt 3

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page(s)

595-607

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cites work

2 references

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16 March 2017

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Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?

3 June 2018

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16 March 2017

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Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man

16 March 2017

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Fat utilization during exercise: adaptation to a fat-rich diet increases utilization of plasma fatty acids and very low density lipoprotein-triacylglycerol in humans

16 March 2017

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Mechanism of free fatty acid-induced insulin resistance in humans

16 March 2017

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Brain Metabolism during Fasting*

16 March 2017

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Global and societal implications of the diabetes epidemic

16 March 2017

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The role of intramuscular lipid in insulin resistance

7 April 2017

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Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity

3 June 2018

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Fasting for 72 h increases intramyocellular lipid content in nondiabetic, physically fit men.

3 June 2018

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Intramuscular triacylglycerol utilization in human skeletal muscle during exercise: is there a controversy?

3 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Muscle long-chain acyl CoA esters and insulin resistance

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Muscle triglyceride and insulin resistance

3 June 2018

1 reference

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The paradoxical nature of hunter-gatherer diets: meat-based, yet non-atherogenic

3 June 2018

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Evolutionary health promotion

3 June 2018

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Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion

3 June 2018

1 reference

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Influence of endurance running and recovery diet on intramyocellular lipid content in women: a 1H NMR study

3 June 2018

1 reference

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Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humans

3 June 2018

1 reference

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The acute versus the chronic response to exercise

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

3 June 2018

1 reference

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Muscle reflex and central motor control of neuroendocrine activity, glucose homeostasis and circulation during exercise.

3 June 2018

1 reference

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Fast elevation of the intramyocellular lipid content in the presence of circulating free fatty acids and hyperinsulinemia: a dynamic 1H-MRS study

3 June 2018

1 reference

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Low-fat diet alters intramuscular substrates and reduces lipolysis and fat oxidation during exercise

3 June 2018

1 reference

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Waging war on modern chronic diseases: primary prevention through exercise biology

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Relation of triglyceride stores in skeletal muscle cells to central obesity and insulin sensitivity in European and South Asian men.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Evaluation of exercise and training on muscle lipid metabolism

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Hypothesis: muscle insulin resistance is the ("not-so") thrifty genotype.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Effect of endurance training on fatty acid metabolism during whole body exercise

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Free fatty acids and exercise

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Weight loss reduces abdominal fat and improves insulin action in middle-aged and older men with impaired glucose tolerance

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Marked Improvement in Carbohydrate and Lipid Metabolism in Diabetic Australian Aborigines After Temporary Reversion to Traditional Lifestyle

3 June 2018

1 reference

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Effects of exercise and lack of exercise on glucose tolerance and insulin sensitivity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Hormone-fuel interrelationships during fasting

3 June 2018

1 reference

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Liver and kidney metabolism during prolonged starvation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

3 June 2018

Starvation and survival

1 reference

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Adaptation of muscle to exercise. Increase in levels of palmityl Coa synthetase, carnitine palmityltransferase, and palmityl Coa dehydrogenase, and in the capacity to oxidize fatty acids

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

The ultrastructure of the normal human skeletal muscle. A morphometric analysis on untrained men, women and well-trained orienteers.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Acute effects of endurance exercise on mitochondrial distribution and skeletal muscle morphology

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Improved insulin action in muscle, liver, and adipose tissue in physically trained human subjects

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Influence of fasting on carbohydrate and fat metabolism during rest and exercise in men.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Glucose turnover in 48-hour-fasted running rats.

3 June 2018

1 reference

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Cold exposure reverses the diabetogenic effects of high-fat feeding.

3 June 2018

1 reference

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Paleolithic nutrition. A consideration of its nature and current implications

3 June 2018

1 reference

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Effects of body composition and exercise capacity on glucose tolerance, insulin, and lipoprotein lipids in healthy older men: a cross-sectional and longitudinal intervention study.

3 June 2018

1 reference

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Cold exposure reverses inhibitory effects of fasting on peripheral glucose uptake in rats

3 June 2018

1 reference

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Effect of starvation on human muscle protein metabolism and its response to insulin.

3 June 2018

1 reference

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The effect of starvation on insulin-induced glucose disposal and thermogenesis in humans

3 June 2018

1 reference

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Effect of decreased availability of substrates on intramuscular triglyceride utilization during exercise.

3 June 2018

1 reference

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Changes in lipoprotein-lipase activity and lipid stores in human skeletal muscle with prolonged heavy exercise

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

3 June 2018

1 reference

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Lipoprotein lipase activity and intramuscular triglyceride stores after long-term high-fat and high-carbohydrate diets in physically trained men.

20 June 2018

1 reference

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Muscle triglyceride utilization during exercise: effect of training.

20 June 2018

1 reference

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Muscle glycogen utilization during shivering thermogenesis in humans.

20 June 2018

1 reference

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Familial, anthropometric, and metabolic associations of intramyocellular lipid levels in prepubertal males

20 June 2018

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Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes

21 January 2018

1 reference

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Effect of cold exposure on fuel utilization in humans: plasma glucose, muscle glycogen, and lipids

21 January 2018

1 reference

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Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

21 January 2018

1 reference

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Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.

21 January 2018

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Intramyocellular triacylglycerol in prolonged cycling with high- and low-carbohydrate availability.

21 January 2018

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Skeletal muscle substrate utilization during submaximal exercise in man: effect of endurance training.

21 January 2018

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Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

21 January 2018

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Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

21 January 2018

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Proton magnetic resonance spectroscopy study of soleus muscle in non-obese healthy and Type 2 diabetic Asian Northern Indian males: high intramyocellular lipid content correlates with excess body fat and abdominal obesity

21 January 2018

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https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.053926

Skeletal muscle triglyceride levels are inversely related to insulin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.053926

Normal insulin sensitivity and IMCL content in overweight humans are associated with higher fasting lipid oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.053926

Intramuscular fatty acid metabolism in contracting and non-contracting human skeletal muscle.

21 January 2018

1 reference

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Effects of dietary protein level and cold exposure on tissue responsiveness and sensitivity to insulin in sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.053926

The increase in intramyocellular lipid content is a very early response to training

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.053926

Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.053926

Intramyocellular lipid is associated with resistance to in vivo insulin actions on glucose uptake, antilipolysis, and early insulin signaling pathways in human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.053926

Effects of Plasma Adrenaline on Hormone‐Sensitive Lipase at Rest and during Moderate Exercise in Human Skeletal Muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.053926

Effects of fasting on fatty acid kinetics and on the cardiovascular, thermogenic and metabolic responses to the glucose clamp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.053926

Postexercise fat intake repletes intramyocellular lipids but no faster in trained than in sedentary subjects.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Free fatty acids inhibit the glucose-stimulated increase of intramuscular glucose-6-phosphate concentration in humans

27 November 2018

1 reference

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Whole-body and adipose tissue glucose metabolism in response to short-term fasting in lean and obese women.

27 November 2018

1 reference

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Stimulation of hormone-sensitive lipase activity by contractions in rat skeletal muscle

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle.

27 November 2018

1 reference

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Effects of changes in body weight on carbohydrate metabolism, catecholamine excretion, and thyroid function

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Distinct effects of aerobic exercise training and weight loss on glucose homeostasis in obese sedentary men.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Effects of endurance training on total fat oxidation in elderly persons

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

The insulin action-fiber type relationship in humans is muscle group specific

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664785

Diabetes, diversity, and disparity: what do we do with the evidence?

27 November 2018

1 reference

12 December 2020

Effects of training duration on substrate turnover and oxidation during exercise

1 reference

12 December 2020

Utilization of skeletal muscle triacylglycerol during postexercise recovery in humans

1 reference

12 December 2020

Muscle contraction increases palmitate esterification and oxidation and triacylglycerol oxidation

1 reference

12 December 2020

Effect of diet on the replenishment of intramyocellular lipids after exercise

1 reference

12 December 2020

Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle

1 reference

12 December 2020

Uptake and release of free fatty acids and other metabolites in the legs of exercising men

1 reference

12 December 2020

Diet, Muscle Glycogen and Physical Performance

1 reference

12 December 2020

Availability of substrates and capacity for prolonged heavy exercise in man

1 reference

12 December 2020

Effect of diet on the utilization of blood-borne and intramuscular substrates during exercise in man

1 reference

12 December 2020

Effect of acute cold exposure on the mobilization of intramuscular glycogen and triglycerides in the rat

1 reference

12 December 2020

Effect of training on insulin-mediated glucose uptake in human muscle

1 reference

12 December 2020

Effect of prolonged exercise on muscle citrate concentration before and after endurance training in men

1 reference

12 December 2020

Gender differences in glucoregulatory responses to intense exercise

1 reference

12 December 2020

Lower calorie intake enhances muscle insulin action and reduces hexosamine levels

1 reference

12 December 2020

Intramuscular glycogen and intramyocellular lipid utilization during prolonged exercise and recovery in man: a 13C and 1H nuclear magnetic resonance spectroscopy study

1 reference

12 December 2020

Endurance training increases FFA oxidation and reduces triacylglycerol utilization in contracting rat soleus

1 reference

12 December 2020

Kinetics of intramuscular triglyceride fatty acids in exercising humans

1 reference

12 December 2020

Effect of endurance training on plasma free fatty acid turnover and oxidation during exercise

1 reference

12 December 2020

Interaction of training and diet on metabolism and endurance during exercise in man

1 reference

12 December 2020

Interrelationships between muscle morphology, insulin action, and adiposity

1 reference

12 December 2020

Changes in insulin action and GLUT-4 with 6 days of inactivity in endurance runners

1 reference

12 December 2020

Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects

1 reference

12 December 2020

Variability of triacylglycerol content in human skeletal muscle biopsy samples

1 reference

12 December 2020

Substrate utilization and enzymes in skeletal muscle of extremely endurance-trained men

1 reference

12 December 2020

Insulin action and secretion in endurance-trained and untrained humans

1 reference

12 December 2020

Effects of acute exercise and detraining on insulin action in trained men

1 reference

12 December 2020

Free fatty acid availability and temperature regulation in cold water

1 reference

12 December 2020

Stimulatory effects of cold exposure and cold acclimation on glucose uptake in rat peripheral tissues

1 reference

12 December 2020

Effects of muscle glycogen and plasma FFA availability on human metabolic responses in cold water

1 reference

12 December 2020

Early adaptations in blood substrates, metabolites, and hormones to prolonged exercise training in man

1 reference

12 December 2020

Increased plasma FFA uptake and oxidation during prolonged exercise in trained vs. untrained humans

1 reference

12 December 2020