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Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
title
Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal
(English)
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
main subject
Estrogen related receptor, beta
1 reference
stated in
GOA release 2020-03-11
stem cell self-renewal
1 reference
based on heuristic
inferred from title
author
Graziano Martello
object named as
Graziano Martello
series ordinal
1
0 references
Austin Smith
object named as
Austin Smith
series ordinal
9
0 references
Berthold Gottgens
series ordinal
7
object named as
Berthold Göttgens
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
author name string
Toshimi Sugimoto
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
Evangelia Diamanti
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
Anagha Joshi
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
Rebecca Hannah
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
Satoshi Ohtsuka
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
Hitoshi Niwa
series ordinal
8
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
language of work or name
English
0 references
publication date
5 October 2012
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
published in
Cell Stem Cell
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
volume
11
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
page(s)
491–504
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stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
issue
4
1 reference
stated in
PubMed
PubMed ID
23040478
retrieved
7 March 2017
cites work
Maintaining embryonic stem cell pluripotency with Wnt signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
An Oct4-centered protein interaction network in embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Dissecting self-renewal in stem cells with RNA interference
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Tcf3: a transcriptional regulator of axis induction in the early embryo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
GSK-3: tricks of the trade for a multi-tasking kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Establishment in culture of pluripotential cells from mouse embryos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
16 March 2017
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
7 April 2017
The ground state of embryonic stem cell self-renewal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
7 April 2017
Control of the embryonic stem cell state
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
7 April 2017
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
7 April 2017
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
7 April 2017
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
7 April 2017
Pluripotency in the embryo and in culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
The transcriptional and epigenomic foundations of ground state pluripotency.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
A PiggyBac-based recessive screening method to identify pluripotency regulators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
The liberation of embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
The ground state of pluripotency.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Design principles of pluripotency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
ChIP-Seq of transcription factors predicts absolute and differential gene expression in embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Nanog is the gateway to the pluripotent ground state.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Klf4 reverts developmentally programmed restriction of ground state pluripotency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Identification and characterization of subpopulations in undifferentiated ES cell culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
How is pluripotency determined and maintained?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
3 June 2018
A compendium of genome-wide hematopoietic transcription factor maps supports the identification of gene regulatory control mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
26 November 2018
Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
26 November 2018
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
26 November 2018
Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
26 November 2018
WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465555
retrieved
26 November 2018
Identifiers
DOI
10.1016/J.STEM.2012.06.008
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1312553
OpenCitations bibliographic resource ID
1312553
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1312553
PMCID
3465555
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1312553
PubMed ID
23040478
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1312553
ResearchGate publication ID
232065124
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