(Q28910204)

30 September 2017

The ER structural protein Rtn4A stabilizes and enhances signaling through the receptor tyrosine kinase ErbB3 (English)

1 reference

positive regulation of ERBB3 signaling pathway

30 September 2017

2 references

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1905580

negative regulation of ERBB3 signaling pathway

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1905579

regulation of ERBB3 signaling pathway

1 reference

Gene Ontology release 2020-05-02

1 reference

Ring finger protein 41

1 reference

Reticulon 4

1 reference

Erb-b2 receptor tyrosine kinase 3

1 reference

Reticulon 4

1 reference

author name string

Jason Hatakeyama

1

1 reference

30 September 2017

Hanine Rafidi

3

1 reference

30 September 2017

Antonio Cuevas

4

1 reference

30 September 2017

Colleen Sweeney

5

1 reference

30 September 2017

Jessica H Wald

2

1 reference

30 September 2017

Kermit L Carraway

6

1 reference

30 September 2017

28 June 2016

1 reference

30 September 2017

1 reference

30 September 2017

9

1 reference

30 September 2017

434

1 reference

30 September 2017

ra65

1 reference

describes a project that uses

30 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5554593/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

A class of membrane proteins shaping the tubular endoplasmic reticulum

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Cell autonomous function of Nogo and reticulons: The emerging story at the endoplasmic reticulum

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Structure-based mutagenesis of the substrate-recognition domain of Nrdp1/FLRF identifies the binding site for the receptor tyrosine kinase ErbB3

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8)

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Neuregulin inhibits acetylcholine receptor aggregation in myotubes

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

E3 ligase FLRF (Rnf41) regulates differentiation of hematopoietic progenitors by governing steady-state levels of cytokine and retinoic acid receptors

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

The E3 ubiquitin ligase neuregulin receptor degradation protein 1 (Nrdp1) promotes M2 macrophage polarization by ubiquitinating and activating transcription factor CCAAT/enhancer-binding Protein β (C/EBPβ)

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Parkin is ubiquitinated by Nrdp1 and abrogates Nrdp1-induced oxidative stress

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.AAF1604

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Nrdp1-mediated ErbB3 degradation inhibits glioma cell migration and invasion by reducing cytoplasmic localization of p27(Kip1).

21 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in β-Cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Endoplasmic reticulum stress-activated cell reprogramming in oncogenesis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

MiR-497 promotes metastasis of colorectal cancer cells through Nrdp1 inhibition

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

The roles of neuregulin-1 in cardiac development, homeostasis, and disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Transcription of Nrdp1 by the androgen receptor is regulated by nuclear filamin A in prostate cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Nrdp1 expression to predict clinical outcome and efficacy of adjuvant anthracyclines-based chemotherapy in breast cancer: A retrospective study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Regulation of ERBB3/HER3 signaling in cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

The role of endoplasmic reticulum stress in human pathology

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Endoplasmic reticulum stress induces different molecular structural alterations in human dilated and ischemic cardiomyopathy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

The diabetes susceptibility gene Clec16a regulates mitophagy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Neuregulin-ErbB4 signaling in the developing lung alveolus: a brief review

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

ERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Oligomerization of the Nrdp1 E3 ubiquitin ligase is necessary for efficient autoubiquitination but not ErbB3 ubiquitination

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Reciprocal cross-regulation between RNF41 and USP8 controls cytokine receptor sorting and processing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

The tripartite motif: structure and function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Endoplasmic reticulum structure and interconnections with other organelles

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Neuregulin in cardiovascular development and disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Neuregulin/ErbB regulate neuromuscular junction development by phosphorylation of α-dystrobrevin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Weaving the web of ER tubules

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Overexpression of Nrdp1 in the heart exacerbates doxorubicin-induced cardiac dysfunction in mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Quantity control of the ErbB3 receptor tyrosine kinase at the endoplasmic reticulum

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Feedback regulation of EGFR signalling: decision making by early and delayed loops.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Mechanisms determining the morphology of the peripheral ER

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Reticulon short hairpin transmembrane domains are used to shape ER tubules

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

E3 ubiquitin ligases in ErbB receptor quantity control

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

The extracellular matrix in development and morphogenesis: a dynamic view

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Mechanisms shaping the membranes of cellular organelles

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Novel anticancer targets: revisiting ERBB2 and discovering ERBB3.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Cisternal organization of the endoplasmic reticulum during mitosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Mechanisms of ErbB receptor negative regulation and relevance in cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Rough sheets and smooth tubules

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

The mucin Muc4 potentiates neuregulin signaling by increasing the cell-surface populations of ErbB2 and ErbB3.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Neuregulin potentiates agrin-induced acetylcholine receptor clustering in myotubes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

ARIA: a neuromuscular junction neuregulin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

ARIA can be released from extracellular matrix through cleavage of a heparin-binding domain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Acetylcholine receptor-inducing activity stimulates expression of the epsilon-subunit gene of the muscle acetylcholine receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

Functions of Nogo proteins and their receptors in the nervous system.

3 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

PirB is a functional receptor for myelin inhibitors of axonal regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

The Nogo-66 receptor NgR1 is required only for the acute growth cone-collapsing but not the chronic growth-inhibitory actions of myelin inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Sheets, ribbons and tubules - how organelles get their shape.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Identification of Nogo as a novel indicator of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Reticulon-4A (Nogo-A) redistributes protein disulfide isomerase to protect mice from SOD1-dependent amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Neural crest cell lineage restricts skeletal muscle progenitor cell differentiation through Neuregulin1-ErbB3 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Neuregulin-induced expression of the acetylcholine receptor requires endocytosis of ErbB receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Nrdp1 inhibits growth of colorectal cancer cells by nuclear retention of p27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Nrdp1 inhibits metastasis of colorectal cancer cells by EGFR signaling-dependent MMP7 modulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Lower expression of Nrdp1 in human glioma contributes tumor progression by reducing apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Cardiac-specific overexpression of E3 ligase Nrdp1 increases ischemia and reperfusion-induced cardiac injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAF1604

Neuregulin-heparan-sulfate proteoglycan interactions produce sustained erbB receptor activation required for the induction of acetylcholine receptors in muscle

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5554593

MCF-10AT: A Model for Human Breast Cancer Development

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27353365

12 December 2020

inferred from PubMed ID database lookup

Synapses form in skeletal muscles lacking neuregulin receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27353365

12 December 2020

inferred from PubMed ID database lookup

Separate pathways for synapse-specific and electrical activity-dependent gene expression in skeletal muscle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27353365

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1126/SCISIGNAL.AAF1604

1 reference

30 September 2017

1 reference

30 September 2017

PubMed publication ID

27353365

1 reference