(Q29013931)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Basic concepts in population modeling, simulation, and model-based drug development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

D R Mould

series ordinal

1

2 references

23 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

publication date

26 September 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json

CPT: pharmacometrics & systems pharmacology

4 March 2020

published in

2 references

23 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

1

2 references

23 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

issue

9

1 reference

23 March 2017

page(s)

e6

2 references

23 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json

Can the pharmaceutical industry reduce attrition rates?

4 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Models for disease progression: new approaches and uses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Impact of pharmacometric analyses on new drug approval and labelling decisions: a review of 198 submissions between 2000 and 2008.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

A Bayesian model averaging approach for estimating the relative risk of mortality associated with heat waves in 105 U.S. cities

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Personalized medicine and genomics: challenges and opportunities in assessing effectiveness, cost-effectiveness, and future research priorities.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Mechanistic basis of using body size and maturation to predict clearance in humans

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Evaluation of structural models to describe the effect of placebo upon the time course of major depressive disorder

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Quantitative disease, drug, and trial models

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Pharmacometrics at FDA: evolution and impact on decisions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Model-based drug development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Whole-body physiologically based pharmacokinetic models

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Non-linear mixed effects modeling - from methodology and software development to driving implementation in drug development science

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

How modeling and simulation have enhanced decision making in new drug development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Clinical trial simulation in drug development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Population pharmacokinetics. A regulatory perspective.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Learning versus confirming in clinical drug development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Intention-to-treat analysis and the goals of clinical trials

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Evaluation of methods for estimating population pharmacokinetic parameters. I. Michaelis-menten model: Routine clinical pharmacokinetic data

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

The population approach to pharmacokinetic data analysis: rationale and standard data analysis methods

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Linearity and superposition in pharmacokinetics.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Population pharmacokinetics. Theory and clinical application

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Population pharmacokinetics and pharmacodynamics of thiopental: the effect of age revisited.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Results and validation of a population pharmacodynamic model for cognitive effects in Alzheimer patients treated with tacrine

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Building population pharmacokineticpharmacodynamic models. I. Models for covariate effects

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Pharmacokinetic analysis using an electrical analogue

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606044

Introduction of quantitative methods in pharmacology and clinical pharmacology: a historical overview.

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2012.4

Continuous patient monitoring with a small digital computer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2012.4

Hydraulic analog for simultaneous representation of pharmacokinetics and pharmacodynamics: application to vecuronium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2012.4

Primary, Secondary, and Meta-Analysis of Research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2012.4

Importance of within subject variation in levodopa pharmacokinetics: a 4 year cohort study in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2012.4

Optimization of individual and population designs using Splus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2012.4

A PK-PD model for predicting the impact of age, CYP2C9, and VKORC1 genotype on individualization of warfarin therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2012.4

Pharmacometrics for regulatory decision making: status and perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2012.4

Using Disease Progression Models as a Tool to Detect Drug Effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2012.4

Spending on new drug development1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FPSP.2012.4

Modelling of individual pharmacokinetics for computer-aided drug dosage

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23835886

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/PSP.2012.4

3 references

23 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

23835886

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23835886%20AND%20SRC:MED&resulttype=core&format=json