(Q29147455)

potassium ion transmembrane transport

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Simon G. Møller

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Yong Yu

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Mahmud Arif Pavel

1

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Caixia Lv

2

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Courtney Ng

3

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Lei Yang

4

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Parul Kashyap

5

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Clarissa Lam

6

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Victoria Valentino

7

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Thomas Campbell

9

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

David Zenisek

11

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Helen Y Fung

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Nathalia G Holtzman

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

3 June 2020

language of work or name

English

0 references

publication date

26 April 2016

1 reference

4 April 2017

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

113

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

issue

17

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

E2363-72

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

3 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4855601/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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6 April 2017

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6 April 2017

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Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2.

6 April 2017

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Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity

6 April 2017

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A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes

6 April 2017

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Structural and molecular basis of the assembly of the TRPP2/PKD1 complex

6 April 2017

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Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

6 April 2017

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TRPP2 and autosomal dominant polycystic kidney disease

6 April 2017

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Regulation of calcium signaling by polycystin-2

6 April 2017

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Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia

6 April 2017

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Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

6 April 2017

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Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice

6 April 2017

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The ion channel polycystin-2 is required for left-right axis determination in mice

6 April 2017

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Polycystin-2 is an intracellular calcium release channel

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Polycystin-L is a calcium-regulated cation channel permeable to calcium ions

6 April 2017

1 reference

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Specific association of the gene product of PKD2 with the TRPC1 channel

6 April 2017

1 reference

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A spectrum of mutations in the second gene for autosomal dominant polycystic kidney disease (PKD2)

6 April 2017

1 reference

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Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

6 April 2017

1 reference

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PKD1 interacts with PKD2 through a probable coiled-coil domain

6 April 2017

1 reference

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PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

An introduction to TRP channels

6 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Cyclic nucleotide-gated ion channels

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Two populations of node monocilia initiate left-right asymmetry in the mouse

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Human polycystin-2 transgene dose-dependently rescues ADPKD phenotypes in Pkd2 mutant mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Filamin-a increases the stability and plasma membrane expression of polycystin-2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Altered trafficking and stability of polycystins underlie polycystic kidney disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Analysis of the cell surface expression of cytokine receptors using the surface protein biotinylation method.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Structural interaction and functional regulation of polycystin-2 by filamin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Calcium-induced conformational changes in C-terminal tail of polycystin-2 are necessary for channel gating

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

The single pore residue Asp523 in PKD2L1 determines Ca2+ permeation of the PKD1L3/PKD2L1 complex.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Forward genetic analysis reveals multiple gating mechanisms of TRPV4

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Polycystins and primary cilia: primers for cell cycle progression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Multiple unbiased prospective screens identify TRP channels and their conserved gating elements

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Polycystic kidney disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Expression cloning of TMEM16A as a calcium-activated chloride channel subunit

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

TRPP2 and TRPV4 form a polymodal sensory channel complex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Regulation of the murine TRPP3 channel by voltage, pH, and changes in cell volume

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Yeast gain-of-function mutations reveal structure-function relationships conserved among different subfamilies of transient receptor potential channels

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Gain-of-function mutation in TRPML3 causes the mouse Varitint-Waddler phenotype

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Evaluating the clinical utility of a molecular genetic test for polycystic kidney disease.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Open channel block by Ca2+ underlies the voltage dependence of drosophila TRPL channel

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Cell biology of polycystin-2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Polycystin-2 immunolocalization and function in zebrafish

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

The versatile nature of the calcium-permeable cation channel TRPP2

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Organic cation permeation through the channel formed by polycystin-2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

The TRP superfamily of cation channels

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Polycystin-1 activates and stabilizes the polycystin-2 channel.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Voltage dependence and pH regulation of human polycystin-2-mediated cation channel activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Molecular genetics and mechanism of autosomal dominant polycystic kidney disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Aberrant splicing in the PKD2 gene as a cause of polycystic kidney disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Identification and characterization of polycystin-2, the PKD2 gene product

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Molecular determinants of a Ca2+-binding site in the pore of cyclic nucleotide-gated channels: S5/S6 segments control affinity of intrapore glutamates

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4855601

Pkd1l1 complexes with Pkd2 on motile cilia and functions to establish the left-right axis.

3 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

PKD2 functions as an epidermal growth factor-activated plasma membrane channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

Nonspecific cation current associated with native polycystin-2 in HEK-293 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

Molecular basis for species-specific sensitivity to "hot" chili peppers

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

Molecular determinants of permeation through the cation channel TRPV4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

PKD2 mutations in a Czech population with autosomal dominant polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

Identification and functional characterization of an N-terminal oligomerization domain for polycystin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

Voltage sensor of Kv1.2: structural basis of electromechanical coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

Single amino acid change in the fifth transmembrane segment of the TRP Ca2+ channel causes massive degeneration of photoreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

The TRPP Subfamily and Polycystin-1 Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

Erratum: Structure of the TRPA1 ion channel suggests regulatory mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1517066113

A transient calcium-dependent chloride current in the immature Xenopus oocyte

21 January 2018

1 reference

12 December 2020

A calcium-dependent transient outward current in Xenopus laevis oocytes

1 reference

12 December 2020

Gating of the polycystin ion channel signaling complex in neurons and kidney cells

1 reference

12 December 2020

Identification of two novel polycystic kidney disease-1-like genes in human and mouse genomes

1 reference

12 December 2020

Submembraneous microtubule cytoskeleton: interaction of TRPP2 with the cell cytoskeleton

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1517066113

2 references

4 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27071085%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

2 references

4 April 2017