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siRNAs can function as miRNAs
scientific article (publication date: 15 February 2003)
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siRNAs can function as miRNAs
(English)
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PubMed
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30 April 2017
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John G Doench
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Doench JG
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30 April 2017
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Petersen CP
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30 April 2017
Sharp PA
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30 April 2017
language of work or name
English
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30 April 2017
publication date
15 February 2003
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30 April 2017
published in
Genes & Development
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30 April 2017
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17
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30 April 2017
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438-42
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30 April 2017
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4
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30 April 2017
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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
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30 April 2017
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
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30 April 2017
miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
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Control of developmental timing by small temporal RNAs: a paradigm for RNA-mediated regulation of gene expression
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Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
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30 April 2017
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
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Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
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Role for a bidentate ribonuclease in the initiation step of RNA interference
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The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
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30 April 2017
The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
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PubMed Central
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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
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Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor
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Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline
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Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.
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3 June 2018
A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=195999
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RNA silencing. Diced defence.
1 reference
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PubMed Central
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retrieved
26 November 2018
Identifiers
DOI
10.1101/GAD.1064703
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12600936
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1102914
OpenCitations bibliographic resource ID
1102914
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1102914
PMCID
195999
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12600936
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1102914
PubMed ID
12600936
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12600936
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1102914
ResearchGate publication ID
10887680
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