(Q29617515)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

0 references

Hsp90 cochaperone SBA1 YKL117W

1 reference

Hsp90 family chaperone HSP82 YPL240C

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Chrisostomos Prodromou

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Laurence Pearl

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Maruf M U Ali

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Philippe Meyer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

S Mark Roe

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Cara K Vaughan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Barry Panaretou

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Peter W Piper

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16625188

19 January 2020

language of work or name

1 reference

30 April 2017

publication date

1 April 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

7087

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

1013-1017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Hsp90 and Cdc37 -- a chaperone cancer conspiracy.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Aha1 competes with Hop, p50 and p23 for binding to the molecular chaperone Hsp90 and contributes to kinase and hormone receptor activation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Ligand-induced conformational shift in the N-terminal domain of GRP94, an Hsp90 chaperone

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

The crystal structure of the carboxy-terminal dimerization domain of htpG, the Escherichia coli Hsp90, reveals a potential substrate binding site

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Structure-activity relationships in purine-based inhibitor binding to HSP90 isoforms

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37)

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

N-terminal residues regulate the catalytic efficiency of the Hsp90 ATPase cycle

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Regulation of Hsp90 ATPase activity by the co-chaperone Cdc37p/p50cdc37.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Stimulation of the weak ATPase activity of human hsp90 by a client protein

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Dimerization and N-terminal domain proximity underlie the function of the molecular chaperone heat shock protein 90

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

SBA1 encodes a yeast hsp90 cochaperone that is homologous to vertebrate p23 proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Two eukaryote-specific regions of Hsp82 are dispensable for its viability and signal transduction functions in yeast

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Isolation of Hsp90 mutants by screening for decreased steroid receptor function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703407

Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04716

The Co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04716

Independent ATPase activity of Hsp90 subunits creates a flexible assembly platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04716

Genetic dissection of p23, an Hsp90 cochaperone, reveals a distinct surface involved in estrogen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04716

Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04716

Biochemical and structural studies of the interaction of Cdc37 with Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04716

Studies with Purified Chaperones Advance the Understanding of the Mechanism of Glucocorticoid Receptor-hsp90 Heterocomplex Assembly

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16625188

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nucleotides and two functional states of hsp90

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16625188

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Binding of p23 and hsp90 during assembly with the progesterone receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16625188

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE04716

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

19 January 2020

1036822838

0 references

OpenCitations bibliographic resource ID

1075505

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16625188%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

16625188

1 reference