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Recent progress in the biology and physiology of sirtuins
scientific article (publication date: 30 July 2009)
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title
Recent progress in the biology and physiology of sirtuins
(English)
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19641587
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30 April 2017
main subject
physiology
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author name string
Finkel T
series ordinal
1
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PubMed
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30 April 2017
Deng CX
series ordinal
2
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19641587
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30 April 2017
Mostoslavsky R
series ordinal
3
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PubMed
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30 April 2017
language of work or name
English
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30 April 2017
publication date
30 July 2009
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retrieved
30 April 2017
published in
Nature
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stated in
PubMed
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30 April 2017
volume
460
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30 April 2017
issue
7255
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stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19641587
retrieved
30 April 2017
page(s)
587-91
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PubMed
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retrieved
30 April 2017
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30 April 2017
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30 April 2017
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A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
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miR-34a repression of SIRT1 regulates apoptosis
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30 April 2017
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
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SIRT1 regulates circadian clock gene expression through PER2 deacetylation
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30 April 2017
Epigenetic control of rDNA loci in response to intracellular energy status
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C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging
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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
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30 April 2017
Negative regulation of the deacetylase SIRT1 by DBC1
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30 April 2017
DBC1 is a negative regulator of SIRT1
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PubMed Central
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30 April 2017
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
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30 April 2017
SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
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30 April 2017
Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity
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30 April 2017
SIRT1 deacetylates and positively regulates the nuclear receptor LXR
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30 April 2017
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
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30 April 2017
SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B
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30 April 2017
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
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30 April 2017
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase
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30 April 2017
SIRT1 regulates the function of the Nijmegen breakage syndrome protein
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Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease
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30 April 2017
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
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30 April 2017
Sirtuins in mammals: insights into their biological function
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30 April 2017
Calorie restriction increases muscle mitochondrial biogenesis in healthy humans
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30 April 2017
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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30 April 2017
Resveratrol improves health and survival of mice on a high-calorie diet
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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30 April 2017
Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction
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PubMed Central
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30 April 2017
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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30 April 2017
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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30 April 2017
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
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PubMed Central
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30 April 2017
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
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30 April 2017
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells
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PubMed Central
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30 April 2017
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
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PubMed Central
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30 April 2017
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
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30 April 2017
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}
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30 April 2017
Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation
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30 April 2017
Sir2-independent life span extension by calorie restriction in yeast
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30 April 2017
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
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30 April 2017
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
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30 April 2017
Mammalian SIRT1 represses forkhead transcription factors
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30 April 2017
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
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30 April 2017
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
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30 April 2017
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
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30 April 2017
Negative control of p53 by Sir2alpha promotes cell survival under stress
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30 April 2017
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
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30 April 2017
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
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A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci
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Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1
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3 June 2018
SIRT1, is it a tumor promoter or tumor suppressor?
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3 June 2018
SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention--the TULIP Study
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3 June 2018
Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis
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3 June 2018
SirT1 gain of function increases energy efficiency and prevents diabetes in mice
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3 June 2018
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
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Sirt1 protects against high-fat diet-induced metabolic damage
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Transcriptional targets of sirtuins in the coordination of mammalian physiology
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3 June 2018
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
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Sirtuins: novel targets for metabolic disease.
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3 June 2018
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
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3 June 2018
SirT1 regulates energy metabolism and response to caloric restriction in mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
SIRT1 controls endothelial angiogenic functions during vascular growth
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1
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PubMed Central
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3 June 2018
Tracking in the Wlds--the hunting of the SIRT and the luring of the Draper
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
Calorie restriction--the SIR2 connection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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3 June 2018
Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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26 November 2018
Sirtuin gene expression in human mononuclear cells is modulated by caloric restriction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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26 November 2018
Association of SIRT1 gene variation with visceral obesity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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26 November 2018
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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26 November 2018
Sirt1 contributes critically to the redox-dependent fate of neural progenitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
retrieved
26 November 2018
Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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26 November 2018
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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26 November 2018
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727385
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26 November 2018
Identifiers
DOI
10.1038/NATURE08197
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19641587
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
747116
Dimensions Publication ID
1016140945
0 references
OpenCitations bibliographic resource ID
747116
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
747116
PMC publication ID
3727385
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19641587
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
747116
PubMed publication ID
19641587
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19641587
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
747116
ResearchGate publication ID
26704304
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