(Q29796453)

http://www.ebi.ac.uk/interpro/protein/G5EEN3

Armadillo-type fold

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/G5EEN3

C2 domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/G5EEN3

Dedicator of cytokinesis, N-terminal domain, protein family

1 reference

DHR-1 domain, protein family

1 reference

DHR-2 domain, protein family

1 reference

SH3 domain, protein family

1 reference

CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration

found in taxon

Caenorhabditis elegans

1 reference

25 May 2022

1 reference

25 May 2022

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 January 2018

Crystal structure of the cell corpse engulfment protein CED-2 in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 January 2018

CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 January 2018

C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 reference

1 January 2018

Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

GTPase regulator activity

IPI

1 reference

1 January 2018

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

protein-containing complex binding

TAS

1 reference

1 January 2018

C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 reference

1 January 2018

CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

guanyl-nucleotide exchange factor complex

TAS

1 reference

1 January 2018

C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

3 references

1 January 2018

Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 January 2018

Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 January 2018

Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

establishment of mitotic spindle orientation

EXP

biological process

1 reference

1 January 2018

The Wnt pathway controls cell death engulfment, spindle orientation, and migration through CED-10/Rac

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

small GTPase mediated signal transduction

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 reference

1 January 2018

Overcoming redundancy: an RNAi enhancer screen for morphogenesis genes in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 reference

1 January 2018

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

intracellular signal transduction

IMP

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

regulation of catalytic activity

IEA

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

left/right axis specification

IEA

1 reference

1 January 2018

The Wnt pathway controls cell death engulfment, spindle orientation, and migration through CED-10/Rac

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

positive regulation of engulfment of apoptotic cell

apoptotic process involved in development

IMP

3 references

1 January 2018

Programmed elimination of cells by caspase-independent cell extrusion in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 January 2018

Caspase-mediated activation of Caenorhabditis elegans CED-8 promotes apoptosis and phosphatidylserine externalization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 January 2018

Caspase-mediated activation of Caenorhabditis elegans CED-8 promotes apoptosis and phosphatidylserine externalization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

positive regulation of distal tip cell migration

synaptic vesicle clustering

IMP

3 references

1 January 2018

Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 January 2018

Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3

1 January 2018

Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EEN3