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English
Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.
scientific article published on 26 March 2012
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Europe PubMed Central
PMC publication ID
3317799
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451697%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 January 2020
title
Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton
(English)
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Europe PubMed Central
PMC publication ID
3317799
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451697%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 January 2020
main subject
cytoskeleton
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Uncharacterized protein CELE_C02F4.1
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GOA release 2020-03-11
author
Andrea K H Stavoe
series ordinal
1
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Europe PubMed Central
PMC publication ID
3317799
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451697%20AND%20SRC:MED&resulttype=core&format=json
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27 January 2020
author name string
Daniel A Colón-Ramos
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2
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Europe PubMed Central
PMC publication ID
3317799
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451697%20AND%20SRC:MED&resulttype=core&format=json
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27 January 2020
language of work or name
English
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publication date
26 March 2012
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3317799
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27 January 2020
number of pages
14
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Journal of Cell Biology
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3317799
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27 January 2020
volume
197
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Europe PubMed Central
PMC publication ID
3317799
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451697%20AND%20SRC:MED&resulttype=core&format=json
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27 January 2020
issue
1
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Europe PubMed Central
PMC publication ID
3317799
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27 January 2020
page(s)
75-88
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Europe PubMed Central
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3317799
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451697%20AND%20SRC:MED&resulttype=core&format=json
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27 January 2020
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11 June 2022
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Netrin participates in the development of retinotectal synaptic connectivity by modulating axon arborization and synapse formation in the developing brain
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CED-10/Rac1 mediates axon guidance by regulating the asymmetric distribution of MIG-10/lamellipodin.
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Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy
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Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.
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Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling
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Glia promote local synaptogenesis through UNC-6 (netrin) signaling in C. elegans
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Versatile fluorescent probes for actin filaments based on the actin-binding domain of utrophin
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Netrin signaling leading to directed growth cone steering.
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Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP.
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11 July 2018
UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation
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The actin cytoskeleton: integrating form and function at the synapse
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11 July 2018
Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion
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11 July 2018
The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C. elegans
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The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism
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11 July 2018
Rac1 and Cdc42 but not RhoA or Rho kinase activities are required for neurite outgrowth induced by the Netrin-1 receptor DCC (deleted in colorectal cancer) in N1E-115 neuroblastoma cells
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The netrin-1 receptor DCC promotes filopodia formation and cell spreading by activating Cdc42 and Rac1.
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CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans
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11 July 2018
The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans
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Visualization of synaptic specializations in live C. elegans with synaptic vesicle protein-GFP fusions
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Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes
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Activation of Rac1 by a Crk SH3-binding protein, DOCK180
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11 July 2018
UNC-115, a conserved protein with predicted LIM and actin-binding domains, mediates axon guidance in C. elegans
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11 July 2018
Genetic analysis of the mechanisms controlling target selection: complementary and combinatorial functions of netrins, semaphorins, and IgCAMs.
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C. elegans cell migration gene mig-10 shares similarities with a family of SH2 domain proteins and acts cell nonautonomously in excretory canal development
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11 July 2018
The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.
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The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans
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11 July 2018
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11 July 2018
UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans
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11 July 2018
Critical roles for the netrin receptor deleted in colorectal cancer in dopaminergic neuronal precursor migration, axon guidance, and axon arborization
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24 September 2018
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SYD-2 Liprin-alpha organizes presynaptic active zone formation through ELKS.
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Identification of genes involved in synaptogenesis using a fluorescent active zone marker in Caenorhabditis elegans.
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24 September 2018
The Abelson tyrosine kinase, the Trio GEF and Enabled interact with the Netrin receptor Frazzled in Drosophila
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24 September 2018
Actin has a molecular scaffolding, not propulsive, role in presynaptic function.
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24 September 2018
The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM.
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24 September 2018
The actin-binding protein UNC-115 is an effector of Rac signaling during axon pathfinding in C. elegans
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24 September 2018
SYD-1, a presynaptic protein with PDZ, C2 and rhoGAP-like domains, specifies axon identity in C. elegans
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24 September 2018
Developmentally regulated changes in cellular compartmentation and synaptic distribution of actin in hippocampal neurons
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24 September 2018
Remodeling of synaptic actin induced by photoconductive stimulation
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24 September 2018
Three C. elegans Rac proteins and several alternative Rac regulators control axon guidance, cell migration and apoptotic cell phagocytosis.
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24 September 2018
A regulatory cascade of three homeobox genes, ceh-10, ttx-3 and ceh-23, controls cell fate specification of a defined interneuron class in C. elegans
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24 September 2018
Stages of synapse development defined by dependence on F-actin.
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24 September 2018
Establishment of left/right asymmetry in neuroblast migration by UNC-40/DCC, UNC-73/Trio and DPY-19 proteins in C. elegans.
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24 September 2018
Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans.
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24 September 2018
Mosaic analysis in the nematode Caenorhabditis elegans
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22451697
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22451697
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1083/JCB.201110127
1 reference
stated in
Europe PubMed Central
PMC publication ID
3317799
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451697%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 January 2020
PMC publication ID
3317799
1 reference
stated in
Europe PubMed Central
PMC publication ID
3317799
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451697%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 January 2020
PubMed publication ID
22451697
1 reference
stated in
Europe PubMed Central
PMC publication ID
3317799
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22451697%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 January 2020
ResearchGate publication ID
221983156
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