(Q46349589)

21 December 2017

title

The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM. (English)

1 reference

21 December 2017

author

Timothy W Yu

2

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21 December 2017

Cornelia Bargmann

object named as

Cornelia I Bargmann

5

0 references

Marc Tessier-Lavigne

4

object named as

Marc Tessier-Lavigne

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21 December 2017

author name string

Zemer Gitai

1

1 reference

21 December 2017

Erik A Lundquist

3

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21 December 2017

language of work or name

English

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publication date

1 January 2003

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21 December 2017

published in

Neuron

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21 December 2017

volume

37

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21 December 2017

page(s)

53-65

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21 December 2017

issue

1

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21 December 2017

Growth cone configuration and advance: a time-lapse study using video-enhanced differential interference contrast microscopy.

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The Drosophila trio plays an essential role in patterning of axons by regulating their directional extension.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The EVH2 domain of the vasodilator-stimulated phosphoprotein mediates tetramerization, F-actin binding, and actin bundle formation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Chimeric axon guidance receptors: the cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Lineage-specific regulators couple cell lineage asymmetry to the transcription of the Caenorhabditis elegans POU gene unc-86 during neurogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Negative regulation of fibroblast motility by Ena/VASP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Cell migration and axon growth cone guidance in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Growth cone motility and guidance

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The cytoskeletons of isolated, neuronal growth cones

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Rac function and regulation during Drosophila development.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The mec-7 beta-tubulin gene of Caenorhabditis elegans is expressed primarily in the touch receptor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

C. elegans slit acts in midline, dorsal-ventral, and anterior-posterior guidance via the SAX-3/Robo receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Calcium signalling in the guidance of nerve growth by netrin-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Plexin B mediates axon guidance in Drosophila by simultaneously inhibiting active Rac and enhancing RhoA signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Characterization of the actin binding properties of the vasodilator-stimulated phosphoprotein VASP.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Rac1 mediates collapsin-1-induced growth cone collapse

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

ced-10 Rac and mig-2 function redundantly and act with unc-73 trio to control the orientation of vulval cell divisions and migrations in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Role of proteins of the Ena/VASP family in actin-based motility of Listeria monocytogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

UNC-115, a conserved protein with predicted LIM and actin-binding domains, mediates axon guidance in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Genes necessary for directed axonal elongation or fasciculation in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The Caenorhabditis elegans unc-60 gene encodes proteins homologous to a family of actin-binding proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

1 reference

7 January 2021

cAMP-dependent growth cone guidance by netrin-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Rac GTPases control axon growth, guidance and branching

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Caenorhabditis elegans unc-51 gene required for axonal elongation encodes a novel serine/threonine kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The netrin-1 receptor DCC promotes filopodia formation and cell spreading by activating Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The molecular biology of axon guidance

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The semaphorin receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

The conserved immunoglobulin superfamily member SAX-3/Robo directs multiple aspects of axon guidance in C. elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

Role of a new Rho family member in cell migration and axon guidance in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2802%2901149-2

7 January 2021

10.1016/S0896-6273(02)01149-2

Identifiers

DOI

1 reference

21 December 2017

PubMed ID

12526772

1 reference

21 December 2017